Differences in Compositions of Gut Bacterial Populations and Bacteriophages in 5–11 Year-Olds Born Preterm Compared to Full Term

by Thilini N. Jayasinghe, Tommi Vatanen, Tommi Vatanen, Valentina Chiavaroli, Sachin Jayan, Elizabeth J. McKenzie, Evelien Adriaenssens, José G. B. Derraik, José G. B. Derraik, Cameron Ekblad, William Schierding, Malcolm R. Battin, Eric B. Thorstensen, David Cameron-Smith, Elizabeth Forbes-Blom, Paul L. Hofman, Nicole C. Roy, Nicole C. Roy, Nicole C. Roy, Gerald W. Tannock, Gerald W. Tannock, Mark H. Vickers, Wayne S. Cutfield, Wayne S. Cutfield, Justin M. O'Sullivan
Published 2020-06-01

Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus.

by Carolina Medina-Gomez, John P Kemp, Karol Estrada, Joel Eriksson, Jeff Liu, Sjur Reppe, David M Evans, Denise H M Heppe, Liesbeth Vandenput, Lizbeth Herrera, Susan M Ring, Claudia J Kruithof, Nicholas J Timpson, M Carola Zillikens, Ole K Olstad, Hou-Feng Zheng, J Brent Richards, Beate St Pourcain, Albert Hofman, Vincent W V Jaddoe, George Davey Smith, Mattias Lorentzon, Kaare M Gautvik, André G Uitterlinden, Robert Brommage, Claes Ohlsson, Jonathan H Tobias, Fernando Rivadeneira
Published 2012-07-01

Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids

by N. Alcala, N. Leblay, A. A. G. Gabriel, L. Mangiante, D. Hervas, T. Giffon, A. S. Sertier, A. Ferrari, J. Derks, A. Ghantous, T. M. Delhomme, A. Chabrier, C. Cuenin, B. Abedi-Ardekani, A. Boland, R. Olaso, V. Meyer, J. Altmuller, F. Le Calvez-Kelm, G. Durand, C. Voegele, S. Boyault, L. Moonen, N. Lemaitre, P. Lorimier, A. C. Toffart, A. Soltermann, J. H. Clement, J. Saenger, J. K. Field, M. Brevet, C. Blanc-Fournier, F. Galateau-Salle, N. Le Stang, P. A. Russell, G. Wright, G. Sozzi, U. Pastorino, S. Lacomme, J. M. Vignaud, V. Hofman, P. Hofman, O. T. Brustugun, M. Lund-Iversen, V. Thomas de Montpreville, L. A. Muscarella, P. Graziano, H. Popper, J. Stojsic, J. F. Deleuze, Z. Herceg, A. Viari, P. Nuernberg, G. Pelosi, A. M. C. Dingemans, M. Milione, L. Roz, L. Brcic, M. Volante, M. G. Papotti, C. Caux, J. Sandoval, H. Hernandez-Vargas, E. Brambilla, E. J. M. Speel, N. Girard, S. Lantuejoul, J. D. McKay, M. Foll, L. Fernandez-Cuesta
Published 2019-08-01

The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels.

by Elisabeth M van Leeuwen, Françoise A S Smouter, Tony Kam-Thong, Nazanin Karbalai, Albert V Smith, Tamara B Harris, Lenore J Launer, Colleen M Sitlani, Guo Li, Jennifer A Brody, Joshua C Bis, Charles C White, Alok Jaiswal, Ben A Oostra, Albert Hofman, Fernando Rivadeneira, Andre G Uitterlinden, Eric Boerwinkle, Christie M Ballantyne, Vilmundur Gudnason, Bruce M Psaty, L Adrienne Cupples, Marjo-Riitta Järvelin, Samuli Ripatti, Aaron Isaacs, Bertram Müller-Myhsok, Lennart C Karssen, Cornelia M van Duijn
Published 2014-01-01

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.

by Yi-Hsiang Hsu, M Carola Zillikens, Scott G Wilson, Charles R Farber, Serkalem Demissie, Nicole Soranzo, Estelle N Bianchi, Elin Grundberg, Liming Liang, J Brent Richards, Karol Estrada, Yanhua Zhou, Atila van Nas, Miriam F Moffatt, Guangju Zhai, Albert Hofman, Joyce B van Meurs, Huibert A P Pols, Roger I Price, Olle Nilsson, Tomi Pastinen, L Adrienne Cupples, Aldons J Lusis, Eric E Schadt, Serge Ferrari, André G Uitterlinden, Fernando Rivadeneira, Timothy D Spector, David Karasik, Douglas P Kiel
Published 2010-06-01

Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns

by Bonnie R. Joubert, Herman T. den Dekker, Janine F. Felix, Jon Bohlin, Symen Ligthart, Emma Beckett, Henning Tiemeier, Joyce B. van Meurs, Andre G. Uitterlinden, Albert Hofman, Siri E. Håberg, Sarah E. Reese, Marjolein J. Peters, Bettina Kulle Andreassen, Eric A. P. Steegers, Roy M. Nilsen, Stein E. Vollset, Øivind Midttun, Per M. Ueland, Oscar H. Franco, Abbas Dehghan, Johan C. de Jongste, Michael C. Wu, Tianyuan Wang, Shyamal D. Peddada, Vincent W. V. Jaddoe, Wenche Nystad, Liesbeth Duijts, Stephanie J. London
Published 2016-02-01

Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium.

by Faye L Norby, Samuel Adamsson Eryd, Maartje N Niemeijer, Lynda M Rose, Albert V Smith, Xiaoyan Yin, Sunil K Agarwal, Dan E Arking, Daniel L Chasman, Lin Y Chen, Mark Eijgelsheim, Gunnar Engström, Oscar H Franco, Jan Heeringa, George Hindy, Albert Hofman, Pamela L Lutsey, Jared W Magnani, David D McManus, Marju Orho-Melander, James S Pankow, Gull Rukh, Christina-Alexandra Schulz, André G Uitterlinden, Christine M Albert, Emelia J Benjamin, Vilmundur Gudnason, J Gustav Smith, Bruno H C Stricker, Alvaro Alonso
Published 2016-01-01

Evaluation of Presumably Disease Causing SCN1A Variants in a Cohort of Common Epilepsy Syndromes.

by Dennis Lal, Eva M Reinthaler, Borislav Dejanovic, Patrick May, Holger Thiele, Anna-Elina Lehesjoki, Günter Schwarz, Erik Riesch, M Arfan Ikram, Cornelia M van Duijn, Andre G Uitterlinden, Albert Hofman, Hannelore Steinböck, Ursula Gruber-Sedlmayr, Birgit Neophytou, Federico Zara, Andreas Hahn, Genetic Commission of the Italian League against Epilepsy, EuroEPINOMICS CoGIE Consortium, Padhraig Gormley, Felicitas Becker, Yvonne G Weber, Maria Roberta Cilio, Wolfram S Kunz, Roland Krause, Fritz Zimprich, Johannes R Lemke, Peter Nürnberg, Thomas Sander, Holger Lerche, Bernd A Neubauer
Published 2016-01-01

Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS.

by Frank P Diekstra, Christiaan G J Saris, Wouter van Rheenen, Lude Franke, Ritsert C Jansen, Michael A van Es, Paul W J van Vught, Hylke M Blauw, Ewout J N Groen, Steve Horvath, Karol Estrada, Fernando Rivadeneira, Albert Hofman, Andre G Uitterlinden, Wim Robberecht, Peter M Andersen, Judith Melki, Vincent Meininger, Orla Hardiman, John E Landers, Robert H Brown, Aleksey Shatunov, Christopher E Shaw, P Nigel Leigh, Ammar Al-Chalabi, Roel A Ophoff, Leonard H van den Berg, Jan H Veldink
Published 2012-01-01

A genome-wide association study identifies five loci influencing facial morphology in Europeans.

by Fan Liu, Fedde van der Lijn, Claudia Schurmann, Gu Zhu, M Mallar Chakravarty, Pirro G Hysi, Andreas Wollstein, Oscar Lao, Marleen de Bruijne, M Arfan Ikram, Aad van der Lugt, Fernando Rivadeneira, André G Uitterlinden, Albert Hofman, Wiro J Niessen, Georg Homuth, Greig de Zubicaray, Katie L McMahon, Paul M Thompson, Amro Daboul, Ralf Puls, Katrin Hegenscheid, Liisa Bevan, Zdenka Pausova, Sarah E Medland, Grant W Montgomery, Margaret J Wright, Carol Wicking, Stefan Boehringer, Timothy D Spector, Tomáš Paus, Nicholas G Martin, Reiner Biffar, Manfred Kayser
Published 2012-09-01

Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.

by Carsten A Böger, Mathias Gorski, Man Li, Michael M Hoffmann, Chunmei Huang, Qiong Yang, Alexander Teumer, Vera Krane, Conall M O'Seaghdha, Zoltán Kutalik, H-Erich Wichmann, Thomas Haak, Eva Boes, Stefan Coassin, Josef Coresh, Barbara Kollerits, Margot Haun, Bernhard Paulweber, Anna Köttgen, Guo Li, Michael G Shlipak, Neil Powe, Shih-Jen Hwang, Abbas Dehghan, Fernando Rivadeneira, André Uitterlinden, Albert Hofman, Jacques S Beckmann, Bernhard K Krämer, Jacqueline Witteman, Murielle Bochud, David Siscovick, Rainer Rettig, Florian Kronenberg, Christoph Wanner, Ravi I Thadhani, Iris M Heid, Caroline S Fox, W H Kao, CKDGen Consortium
Published 2011-09-01

Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.

by John P Kemp, Carolina Medina-Gomez, Karol Estrada, Beate St Pourcain, Denise H M Heppe, Nicole M Warrington, Ling Oei, Susan M Ring, Claudia J Kruithof, Nicholas J Timpson, Lisa E Wolber, Sjur Reppe, Kaare Gautvik, Elin Grundberg, Bing Ge, Bram van der Eerden, Jeroen van de Peppel, Matthew A Hibbs, Cheryl L Ackert-Bicknell, Kwangbom Choi, Daniel L Koller, Michael J Econs, Frances M K Williams, Tatiana Foroud, M Carola Zillikens, Claes Ohlsson, Albert Hofman, André G Uitterlinden, George Davey Smith, Vincent W V Jaddoe, Jonathan H Tobias, Fernando Rivadeneira, David M Evans
Published 2014-06-01

Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size.

by Nicole Soranzo, Fernando Rivadeneira, Usha Chinappen-Horsley, Ida Malkina, J Brent Richards, Naomi Hammond, Lisette Stolk, Alexandra Nica, Michael Inouye, Albert Hofman, Jonathan Stephens, Eleanor Wheeler, Pascal Arp, Rhian Gwilliam, P Mila Jhamai, Simon Potter, Amy Chaney, Mohammed J R Ghori, Radhi Ravindrarajah, Sergey Ermakov, Karol Estrada, Huibert A P Pols, Frances M Williams, Wendy L McArdle, Joyce B van Meurs, Ruth J F Loos, Emmanouil T Dermitzakis, Kourosh R Ahmadi, Deborah J Hart, Willem H Ouwehand, Nicholas J Wareham, Inês Barroso, Manjinder S Sandhu, David P Strachan, Gregory Livshits, Timothy D Spector, André G Uitterlinden, Panos Deloukas
Published 2009-04-01

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.

by Martha C Castaño-Betancourt, Dan S Evans, Yolande F M Ramos, Cindy G Boer, Sarah Metrustry, Youfang Liu, Wouter den Hollander, Jeroen van Rooij, Virginia B Kraus, Michelle S Yau, Braxton D Mitchell, Kenneth Muir, Albert Hofman, Michael Doherty, Sally Doherty, Weiya Zhang, Robert Kraaij, Fernando Rivadeneira, Elizabeth Barrett-Connor, Rose A Maciewicz, Nigel Arden, Rob G H H Nelissen, Margreet Kloppenburg, Joanne M Jordan, Michael C Nevitt, Eline P Slagboom, Deborah J Hart, Floris Lafeber, Unnur Styrkarsdottir, Eleftheria Zeggini, Evangelos Evangelou, Tim D Spector, Andre G Uitterlinden, Nancy E Lane, Ingrid Meulenbelt, Ana M Valdes, Joyce B J van Meurs
Published 2016-10-01

Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.

by Tamra E Meyer, Germaine C Verwoert, Shih-Jen Hwang, Nicole L Glazer, Albert V Smith, Frank J A van Rooij, Georg B Ehret, Eric Boerwinkle, Janine F Felix, Tennille S Leak, Tamara B Harris, Qiong Yang, Abbas Dehghan, Thor Aspelund, Ronit Katz, Georg Homuth, Thomas Kocher, Rainer Rettig, Janina S Ried, Christian Gieger, Hanna Prucha, Arne Pfeufer, Thomas Meitinger, Josef Coresh, Albert Hofman, Mark J Sarnak, Yii-Der Ida Chen, André G Uitterlinden, Aravinda Chakravarti, Bruce M Psaty, Cornelia M van Duijn, W H Linda Kao, Jacqueline C M Witteman, Vilmundur Gudnason, David S Siscovick, Caroline S Fox, Anna Köttgen, Genetic Factors for Osteoporosis Consortium, Meta Analysis of Glucose and Insulin Related Traits Consortium
Published 2010-08-01

A meta-analysis of gene expression signatures of blood pressure and hypertension.

by Tianxiao Huan, Tõnu Esko, Marjolein J Peters, Luke C Pilling, Katharina Schramm, Claudia Schurmann, Brian H Chen, Chunyu Liu, Roby Joehanes, Andrew D Johnson, Chen Yao, Sai-Xia Ying, Paul Courchesne, Lili Milani, Nalini Raghavachari, Richard Wang, Poching Liu, Eva Reinmaa, Abbas Dehghan, Albert Hofman, André G Uitterlinden, Dena G Hernandez, Stefania Bandinelli, Andrew Singleton, David Melzer, Andres Metspalu, Maren Carstensen, Harald Grallert, Christian Herder, Thomas Meitinger, Annette Peters, Michael Roden, Melanie Waldenberger, Marcus Dörr, Stephan B Felix, Tanja Zeller, International Consortium for Blood Pressure GWAS (ICBP), Ramachandran Vasan, Christopher J O'Donnell, Peter J Munson, Xia Yang, Holger Prokisch, Uwe Völker, Joyce B J van Meurs, Luigi Ferrucci, Daniel Levy
Published 2015-03-01

Early cave art and ancient DNA record the origin of European bison

by Julien Soubrier, Graham Gower, Kefei Chen, Stephen M. Richards, Bastien Llamas, Kieren J. Mitchell, Simon Y. W. Ho, Pavel Kosintsev, Michael S. Y. Lee, Gennady Baryshnikov, Ruth Bollongino, Pere Bover, Joachim Burger, David Chivall, Evelyne Crégut-Bonnoure, Jared E. Decker, Vladimir B. Doronichev, Katerina Douka, Damien A. Fordham, Federica Fontana, Carole Fritz, Jan Glimmerveen, Liubov V. Golovanova, Colin Groves, Antonio Guerreschi, Wolfgang Haak, Tom Higham, Emilia Hofman-Kamińska, Alexander Immel, Marie-Anne Julien, Johannes Krause, Oleksandra Krotova, Frauke Langbein, Greger Larson, Adam Rohrlach, Amelie Scheu, Robert D. Schnabel, Jeremy F. Taylor, Małgorzata Tokarska, Gilles Tosello, Johannes van der Plicht, Ayla van Loenen, Jean-Denis Vigne, Oliver Wooley, Ludovic Orlando, Rafał Kowalczyk, Beth Shapiro, Alan Cooper
Published 2016-10-01

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.

by Guangju Zhai, Alexander Teumer, Lisette Stolk, John R B Perry, Liesbeth Vandenput, Andrea D Coviello, Annemarie Koster, Jordana T Bell, Shalender Bhasin, Joel Eriksson, Anna Eriksson, Florian Ernst, Luigi Ferrucci, Timothy M Frayling, Daniel Glass, Elin Grundberg, Robin Haring, Asa K Hedman, Albert Hofman, Douglas P Kiel, Heyo K Kroemer, Yongmei Liu, Kathryn L Lunetta, Marcello Maggio, Mattias Lorentzon, Massimo Mangino, David Melzer, Iva Miljkovic, MuTHER Consortium, Alexandra Nica, Brenda W J H Penninx, Ramachandran S Vasan, Fernando Rivadeneira, Kerrin S Small, Nicole Soranzo, André G Uitterlinden, Henry Völzke, Scott G Wilson, Li Xi, Wei Vivian Zhuang, Tamara B Harris, Joanne M Murabito, Claes Ohlsson, Anna Murray, Frank H de Jong, Tim D Spector, Henri Wallaschofski
Published 2011-04-01