Do changes in DNA methylation mediate or interact with SNP variation? A pharmacoepigenetic analysis

by Virginia A. Fisher, Lan Wang, Xuan Deng, Chloé Sarnowski, L. Adrienne Cupples, Ching-Ti Liu
Published 2018-09-01

Revisiting methods for modeling longitudinal and survival data: Framingham Heart Study

by Julius S. Ngwa, Howard J. Cabral, Debbie M. Cheng, David R. Gagnon, Michael P. LaValley, L. Adrienne Cupples
Published 2021-02-01

Approaches to detect genetic effects that differ between two strata in genome-wide meta-analyses: Recommendations based on a systematic evaluation.

by Thomas W Winkler, Anne E Justice, L Adrienne Cupples, Florian Kronenberg, Zoltán Kutalik, Iris M Heid, GIANT consortium
Published 2017-01-01

Association of the A-204C polymorphism in the cholesterol 7α-hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring Study...

by Patrick Couture, James D. Otvos, L. Adrienne Cupples, Peter W.F. Wilson, Ernst J. Schaefer, Jose M. Ordovas
Published 1999-10-01

Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study

by Chao-Qiang Lai, Serkalem Demissie, L. Adrienne Cupples, Yueping Zhu, Xian Adiconis, Laurence D. Parnell, Dolores Corella, Jose M. Ordovas
Published 2004-11-01

A comparison of time dependent Cox regression, pooled logistic regression and cross sectional pooling with simulations and an application to the Framingham Heart Study

by Julius S. Ngwa, Howard J. Cabral, Debbie M. Cheng, Michael J. Pencina, David R. Gagnon, Michael P. LaValley, L. Adrienne Cupples
Published 2016-11-01

Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease[S]

by Gina M. Peloso, Serkalem Demissie, Dorothea Collins, Daniel B. Mirel, Stacey B. Gabriel, L. Adrienne Cupples, Sander J. Robins, Ernst J. Schaefer, Margaret E. Brousseau
Published 2010-12-01

Association of APOE genotype with carotid atherosclerosis in men and women

by Roberto Elosua, Jose M. Ordovas, L. Adrienne Cupples, Caroline S. Fox, Joseph F. Polak, Philip A. Wolf, Ralph A. D’Agostino, Sr., Christopher J. O’Donnell
Published 2004-10-01

Network analysis of drug effect on triglyceride-associated DNA methylation

by Elise Lim, Hanfei Xu, Peitao Wu, Daniel Posner, Jiayi Wu, Gina M. Peloso, Achilleas N. Pitsillides, Anita L. DeStefano, L. Adrienne Cupples, Ching-Ti Liu
Published 2018-09-01

A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses.

by Thomas J Baranski, Aldi T Kraja, Jill L Fink, Mary Feitosa, Petra A Lenzini, Ingrid B Borecki, Ching-Ti Liu, L Adrienne Cupples, Kari E North, Michael A Province
Published 2018-04-01

Polymorphisms in the gene encoding lipoprotein lipase in men with low HDL-C and coronary heart disease

by Margaret E. Brousseau, Allison L. Goldkamp, Dorothea Collins, Serkalem Demissie, Allison C. Connolly, L. Adrienne Cupples, Jose M. Ordovas, Hanna E. Bloomfield, Sander J. Robins, Ernst J. Schaefer
Published 2004-10-01

The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site.

by Kris Richardson, Qiong Louie-Gao, Donna K Arnett, Laurence D Parnell, Chao-Qiang Lai, Alberto Davalos, Caroline S Fox, Serkalem Demissie, L Adrienne Cupples, Carlos Fernandez-Hernando, Jose M Ordovas
Published 2011-04-01

Variants at the APOA5 locus, association with carotid atherosclerosis, and modification by obesity: the Framingham Study

by Roberto Elosua, Jose M. Ordovas, L. Adrienne Cupples, Chao-Qiang Lai, Serkalem Demissie, Caroline S. Fox, Joseph F. Polak, Philip A. Wolf, Ralph B. D'Agostino, Sr., Christopher J. O'Donnell
Published 2006-05-01

Genome-wide linkage analyses and candidate gene fine mapping for HDL3 cholesterol: the Framingham Study

by Qiong Yang, Chao-Qiang Lai, Laurence Parnell, L. Adrienne Cupples, Xian Adiconis, Yueping Zhu, Peter W.F. Wilson, David E. Housman, Amanda M. Shearman, Ralph B. D'Agostino, Jose M. Ordovas
Published 2005-07-01

Lipoprotein(a) levels, apo(a) isoform size, and coronary heart disease risk in the Framingham Offspring Study

by Stefania Lamon-Fava, Santica M. Marcovina, John J. Albers, Hal Kennedy, Carl DeLuca, Charles C. White, L. Adrienne Cupples, Judith R. McNamara, Leo J. Seman, Vanina Bongard, Ernst J. Schaefer
Published 2011-06-01

Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol.

by Sumeet A Khetarpal, Andrew C Edmondson, Avanthi Raghavan, Hemanth Neeli, Weijun Jin, Karen O Badellino, Serkalem Demissie, Alisa K Manning, Stephanie L DerOhannessian, Megan L Wolfe, L Adrienne Cupples, Mingyao Li, Sekar Kathiresan, Daniel J Rader
Published 2011-12-01

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.

by Daniel I Chasman, Guillaume Paré, Samia Mora, Jemma C Hopewell, Gina Peloso, Robert Clarke, L Adrienne Cupples, Anders Hamsten, Sekar Kathiresan, Anders Mälarstig, José M Ordovas, Samuli Ripatti, Alex N Parker, Joseph P Miletich, Paul M Ridker
Published 2009-11-01

Population genomic analysis of 962 whole genome sequences of humans reveals natural selection in non-coding regions.

by Fuli Yu, Jian Lu, Xiaoming Liu, Elodie Gazave, Diana Chang, Srilakshmi Raj, Haley Hunter-Zinck, Ran Blekhman, Leonardo Arbiza, Cris Van Hout, Alanna Morrison, Andrew D Johnson, Joshua Bis, L Adrienne Cupples, Bruce M Psaty, Donna Muzny, Jin Yu, Richard A Gibbs, Alon Keinan, Andrew G Clark, Eric Boerwinkle
Published 2015-01-01

Variant-specific inflation factors for assessing population stratification at the phenotypic variance level

by Tamar Sofer, Xiuwen Zheng, Cecelia A. Laurie, Stephanie M. Gogarten, Jennifer A. Brody, Matthew P. Conomos, Joshua C. Bis, Timothy A. Thornton, Adam Szpiro, Jeffrey R. O’Connell, Ethan M. Lange, Yan Gao, L. Adrienne Cupples, Bruce M. Psaty, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Kenneth M. Rice
Published 2021-06-01

Genome-wide association of pericardial fat identifies a unique locus for ectopic fat.

by Caroline S Fox, Charles C White, Kurt Lohman, Nancy Heard-Costa, Paul Cohen, Yingying Zhang, Andrew D Johnson, Valur Emilsson, Ching-Ti Liu, Y-D Ida Chen, Kent D Taylor, Matthew Allison, Matthew Budoff, CARDIoGRAM Consortium, Jerome I Rotter, J Jeffrey Carr, Udo Hoffmann, Jingzhong Ding, L Adrienne Cupples, Yongmei Liu
Published 2012-01-01