Fasting and time of day independently modulate circadian rhythm relevant gene expression in adipose and skin tissue

by Alexessander Couto Alves, Craig A. Glastonbury, Julia S. El-Sayed Moustafa, Kerrin S. Small
Published 2018-09-01

Nuclear genetic regulation of the human mitochondrial transcriptome

by Aminah T Ali, Lena Boehme, Guillermo Carbajosa, Vlad C Seitan, Kerrin S Small, Alan Hodgkinson
Published 2019-02-01

The rate of nonallelic homologous recombination in males is highly variable, correlated between monozygotic twins and independent of age.

by Jacqueline A L MacArthur, Timothy D Spector, Sarah J Lindsay, Massimo Mangino, Raj Gill, Kerrin S Small, Matthew E Hurles
Published 2014-03-01

Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age

by Antonino Zito, Matthew N. Davies, Pei-Chien Tsai, Susanna Roberts, Rosa Andres-Ejarque, Stefano Nardone, Jordana T. Bell, Chloe C. Y. Wong, Kerrin S. Small
Published 2019-11-01

Genetic interactions affecting human gene expression identified by variance association mapping

by Andrew Anand Brown, Alfonso Buil, Ana Viñuela, Tuuli Lappalainen, Hou-Feng Zheng, J Brent Richards, Kerrin S Small, Timothy D Spector, Emmanouil T Dermitzakis, Richard Durbin
Published 2014-04-01

Epigenetic findings in periodontitis in UK twins: a cross-sectional study

by Yuko Kurushima, Pei-Chien Tsai, Juan Castillo-Fernandez, Alexessander Couto Alves, Julia Sarah El-Sayed Moustafa, Caroline Le Roy, Tim D. Spector, Mark Ide, Francis J. Hughes, Kerrin S. Small, Claire J. Steves, Jordana T. Bell
Published 2019-02-01

The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue.

by Alexander W Drong, George Nicholson, Asa K Hedman, Eshwar Meduri, Elin Grundberg, Kerrin S Small, So-Youn Shin, Jordana T Bell, Fredrik Karpe, Nicole Soranzo, Tim D Spector, Mark I McCarthy, Panos Deloukas, Mattias Rantalainen, Cecilia M Lindgren, MolPAGE Consortia
Published 2013-01-01

Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus

by Christopher A. Odhams, Amy L. Roberts, Susan K. Vester, Carolina S. T. Duarte, Charlie T. Beales, Alexander J. Clarke, Sonja Lindinger, Samuel J. Daffern, Antonino Zito, Lingyan Chen, Leonardo L. Jones, Lora Boteva, David L. Morris, Kerrin S. Small, Michelle M. A. Fernando, Deborah S. Cunninghame Graham, Timothy J. Vyse
Published 2019-05-01

Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

by David Z. Pan, Kristina M. Garske, Marcus Alvarez, Yash V. Bhagat, James Boocock, Elina Nikkola, Zong Miao, Chelsea K. Raulerson, Rita M. Cantor, Mete Civelek, Craig A. Glastonbury, Kerrin S. Small, Michael Boehnke, Aldons J. Lusis, Janet S. Sinsheimer, Karen L. Mohlke, Markku Laakso, Päivi Pajukanta, Arthur Ko
Published 2018-08-01

Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

by David Z. Pan, Kristina M. Garske, Marcus Alvarez, Yash V. Bhagat, James Boocock, Elina Nikkola, Zong Miao, Chelsea K. Raulerson, Rita M. Cantor, Mete Civelek, Craig A. Glastonbury, Kerrin S. Small, Michael Boehnke, Aldons J. Lusis, Janet S. Sinsheimer, Karen L. Mohlke, Markku Laakso, Päivi Pajukanta, Arthur Ko
Published 2018-04-01

RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro

by Nellie Y. Loh, James E. N. Minchin, Katherine E. Pinnick, Manu Verma, Marijana Todorčević, Nathan Denton, Julia El-Sayed Moustafa, John P. Kemp, Celia L. Gregson, David M. Evans, Matt J. Neville, Kerrin S. Small, Mark I. McCarthy, Anubha Mahajan, John F. Rawls, Fredrik Karpe, Constantinos Christodoulides
Published 2020-06-01

Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health

by Pei-Chien Tsai, Craig A. Glastonbury, Melissa N. Eliot, Sailalitha Bollepalli, Idil Yet, Juan E. Castillo-Fernandez, Elena Carnero-Montoro, Thomas Hardiman, Tiphaine C. Martin, Alice Vickers, Massimo Mangino, Kirsten Ward, Kirsi H. Pietiläinen, Panos Deloukas, Tim D. Spector, Ana Viñuela, Eric B. Loucks, Miina Ollikainen, Karl T. Kelsey, Kerrin S. Small, Jordana T. Bell
Published 2018-10-01

Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information

by Sebastian Guelfi, Karishma D’Sa, Juan A. Botía, Jana Vandrovcova, Regina H. Reynolds, David Zhang, Daniah Trabzuni, Leonardo Collado-Torres, Andrew Thomason, Pedro Quijada Leyton, Sarah A. Gagliano Taliun, Mike A. Nalls, International Parkinson’s Disease Genomics Consortium (IPDGC), UK Brain Expression Consortium (UKBEC), Kerrin S. Small, Colin Smith, Adaikalavan Ramasamy, John Hardy, Michael E. Weale, Mina Ryten
Published 2020-02-01

Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population.

by Jordana T Bell, Pei-Chien Tsai, Tsun-Po Yang, Ruth Pidsley, James Nisbet, Daniel Glass, Massimo Mangino, Guangju Zhai, Feng Zhang, Ana Valdes, So-Youn Shin, Emma L Dempster, Robin M Murray, Elin Grundberg, Asa K Hedman, Alexandra Nica, Kerrin S Small, MuTHER Consortium, Emmanouil T Dermitzakis, Mark I McCarthy, Jonathan Mill, Tim D Spector, Panos Deloukas
Published 2012-01-01

Further evidence supporting a potential role for ADH1B in obesity

by Liza D. Morales, Douglas T. Cromack, Devjit Tripathy, Marcel Fourcaudot, Satish Kumar, Joanne E. Curran, Melanie Carless, Harald H. H. Göring, Shirley L. Hu, Juan Carlos Lopez-Alvarenga, Kristina M. Garske, Päivi Pajukanta, Kerrin S. Small, Craig A. Glastonbury, Swapan K. Das, Carl Langefeld, Robert L. Hanson, Wen-Chi Hsueh, Luke Norton, Rector Arya, Srinivas Mummidi, John Blangero, Ralph A. DeFronzo, Ravindranath Duggirala, Christopher P. Jenkinson
Published 2021-01-01

Extent, causes, and consequences of small RNA expression variation in human adipose tissue.

by Leopold Parts, Åsa K Hedman, Sarah Keildson, Andrew J Knights, Cei Abreu-Goodger, Martijn van de Bunt, José Afonso Guerra-Assunção, Nenad Bartonicek, Stijn van Dongen, Reedik Mägi, James Nisbet, Amy Barrett, Mattias Rantalainen, Alexandra C Nica, Michael A Quail, Kerrin S Small, Daniel Glass, Anton J Enright, John Winn, MuTHER Consortium, Panos Deloukas, Emmanouil T Dermitzakis, Mark I McCarthy, Timothy D Spector, Richard Durbin, Cecilia M Lindgren
Published 2012-01-01

Correction: Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations.

by Gavin Band, Quang Si Le, Luke Jostins, Matti Pirinen, Katja Kivinen, Muminatou Jallow, Fatoumatta Sisay-Joof, Kalifa Bojang, Margaret Pinder, Giorgio Sirugo, David J. Conway, Vysaul Nyirongo, David Kachala, Malcolm Molyneux, Terrie Taylor, Carolyne Ndila, Norbert Peshu, Kevin Marsh, Thomas N. Williams, Daniel Alcock, Robert Andrews, Sarah Edkins, Emma Gray, Christina Hubbart, Anna Jeffreys, Kate Rowlands, Kathrin Schuldt, Taane G. Clark, Kerrin S. Small, Yik Ying Teo, Dominic P. Kwiatkowski, Kirk A. Rockett, Jeffrey C. Barrett, Chris C. A. Spencer
Published 2013-06-01

Correction: Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations

by Gavin Band, Quang Si Le, Luke Jostins, Matti Pirinen, Katja Kivinen, Muminatou Jallow, Fatoumatta Sisay-Joof, Kalifa Bojang, Margaret Pinder, Giorgio Sirugo, David J. Conway, Vysaul Nyirongo, David Kachala, Malcolm Molyneux, Terrie Taylor, Carolyne Ndila, Norbert Peshu, Kevin Marsh, Thomas N. Williams, Daniel Alcock, Robert Andrews, Sarah Edkins, Emma Gray, Christina Hubbart, Anna Jeffreys, Kate Rowlands, Kathrin Schuldt, Taane G. Clark, Kerrin S. Small, Yik Ying Teo, Dominic P. Kwiatkowski, Kirk A. Rockett, Jeffrey C. Barrett, Chris C. A. Spencer, Malaria Genomic Epidemiology Network
Published 2013-06-01

Imputation-based meta-analysis of severe malaria in three African populations.

by Gavin Band, Quang Si Le, Luke Jostins, Matti Pirinen, Katja Kivinen, Muminatou Jallow, Fatoumatta Sisay-Joof, Kalifa Bojang, Margaret Pinder, Giorgio Sirugo, David J Conway, Vysaul Nyirongo, David Kachala, Malcolm Molyneux, Terrie Taylor, Carolyne Ndila, Norbert Peshu, Kevin Marsh, Thomas N Williams, Daniel Alcock, Robert Andrews, Sarah Edkins, Emma Gray, Christina Hubbart, Anna Jeffreys, Kate Rowlands, Kathrin Schuldt, Taane G Clark, Kerrin S Small, Yik Ying Teo, Dominic P Kwiatkowski, Kirk A Rockett, Jeffrey C Barrett, Chris C A Spencer, Malaria Genomic Epidemiology Network, Malaria Genomic Epidemiological Network
Published 2013-05-01

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.

by Guangju Zhai, Alexander Teumer, Lisette Stolk, John R B Perry, Liesbeth Vandenput, Andrea D Coviello, Annemarie Koster, Jordana T Bell, Shalender Bhasin, Joel Eriksson, Anna Eriksson, Florian Ernst, Luigi Ferrucci, Timothy M Frayling, Daniel Glass, Elin Grundberg, Robin Haring, Asa K Hedman, Albert Hofman, Douglas P Kiel, Heyo K Kroemer, Yongmei Liu, Kathryn L Lunetta, Marcello Maggio, Mattias Lorentzon, Massimo Mangino, David Melzer, Iva Miljkovic, MuTHER Consortium, Alexandra Nica, Brenda W J H Penninx, Ramachandran S Vasan, Fernando Rivadeneira, Kerrin S Small, Nicole Soranzo, André G Uitterlinden, Henry Völzke, Scott G Wilson, Li Xi, Wei Vivian Zhuang, Tamara B Harris, Joanne M Murabito, Claes Ohlsson, Anna Murray, Frank H de Jong, Tim D Spector, Henri Wallaschofski
Published 2011-04-01