Functional validation of GWAS gene candidates for abnormal liver function during zebrafish liver development

by Leah Y. Liu, Caroline S. Fox, Trista E. North, Wolfram Goessling
Published 2013-09-01

The Association between Non-Invasive Hepatic Fibrosis Markers and Cardiometabolic Risk Factors in the Framingham Heart Study.

by Michelle T Long, Alison Pedley, Joseph M Massaro, Udo Hoffmann, Caroline S Fox
Published 2016-01-01

Raising the bar: Recovery ambition for species at risk in Canada and the US.

by Kylee A Pawluk, Caroline H Fox, Christina N Service, Eva H Stredulinsky, Heather M Bryan
Published 2019-01-01

Trends in extinction risk for imperiled species in Canada.

by Brett Favaro, Danielle C Claar, Caroline H Fox, Cameron Freshwater, Jessica J Holden, Allan Roberts, UVic Research Derby
Published 2014-01-01

Cross-sectoral input for the potential role of science in Canada’s environmental assessment

by Aerin L. Jacob, Jonathan W. Moore, Caroline H. Fox, Emily J. Sunter, Danielle Gauthier, Alana R. Westwood, Adam T. Ford
Published 2018-05-01

Using family-based imputation in genome-wide association studies with large complex pedigrees: the Framingham Heart Study.

by Ming-Huei Chen, Jie Huang, Wei-Min Chen, Martin G Larson, Caroline S Fox, Ramachandran S Vasan, Sudha Seshadri, Christopher J O'Donnell, Qiong Yang
Published 2012-01-01

Association of APOE genotype with carotid atherosclerosis in men and women

by Roberto Elosua, Jose M. Ordovas, L. Adrienne Cupples, Caroline S. Fox, Joseph F. Polak, Philip A. Wolf, Ralph A. D’Agostino, Sr., Christopher J. O’Donnell
Published 2004-10-01

The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site.

by Kris Richardson, Qiong Louie-Gao, Donna K Arnett, Laurence D Parnell, Chao-Qiang Lai, Alberto Davalos, Caroline S Fox, Serkalem Demissie, L Adrienne Cupples, Carlos Fernandez-Hernando, Jose M Ordovas
Published 2011-04-01

Variants at the APOA5 locus, association with carotid atherosclerosis, and modification by obesity: the Framingham Study

by Roberto Elosua, Jose M. Ordovas, L. Adrienne Cupples, Chao-Qiang Lai, Serkalem Demissie, Caroline S. Fox, Joseph F. Polak, Philip A. Wolf, Ralph B. D'Agostino, Sr., Christopher J. O'Donnell
Published 2006-05-01

Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing.

by Anna Köttgen, Qiong Yang, Lawrence C Shimmin, Adrienne Tin, Céline Schaeffer, Josef Coresh, Xuan Liu, Luca Rampoldi, Shih-Jen Hwang, Eric Boerwinkle, James E Hixson, W H Linda Kao, Caroline S Fox
Published 2012-01-01

Epigenome-wide association studies identify DNA methylation associated with kidney function

by Audrey Y. Chu, Adrienne Tin, Pascal Schlosser, Yi-An Ko, Chengxiang Qiu, Chen Yao, Roby Joehanes, Morgan E. Grams, Liming Liang, Caroline A. Gluck, Chunyu Liu, Josef Coresh, Shih-Jen Hwang, Daniel Levy, Eric Boerwinkle, James S. Pankow, Qiong Yang, Myriam Fornage, Caroline S. Fox, Katalin Susztak, Anna Köttgen
Published 2017-11-01

Genome-wide association of pericardial fat identifies a unique locus for ectopic fat.

by Caroline S Fox, Charles C White, Kurt Lohman, Nancy Heard-Costa, Paul Cohen, Yingying Zhang, Andrew D Johnson, Valur Emilsson, Ching-Ti Liu, Y-D Ida Chen, Kent D Taylor, Matthew Allison, Matthew Budoff, CARDIoGRAM Consortium, Jerome I Rotter, J Jeffrey Carr, Udo Hoffmann, Jingzhong Ding, L Adrienne Cupples, Yongmei Liu
Published 2012-01-01

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.

by Caroline S Fox, Yongmei Liu, Charles C White, Mary Feitosa, Albert V Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D Johnson, Meredith C Foster, Danielle M Greenawalt, Paula Griffin, Jinghong Ding, Anne B Newman, Fran Tylavsky, Iva Miljkovic, Stephen B Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J Jeffrey Carr, Vilmunder Gudnason, Tamara B Harris, L Adrienne Cupples, Ingrid B Borecki
Published 2012-01-01

Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels

by Adrienne Tin, Yong Li, Jennifer A. Brody, Teresa Nutile, Audrey Y. Chu, Jennifer E. Huffman, Qiong Yang, Ming-Huei Chen, Cassianne Robinson-Cohen, Aurélien Macé, Jun Liu, Ayşe Demirkan, Rossella Sorice, Sanaz Sedaghat, Melody Swen, Bing Yu, Sahar Ghasemi, Alexanda Teumer, Peter Vollenweider, Marina Ciullo, Meng Li, André G. Uitterlinden, Robert Kraaij, Najaf Amin, Jeroen van Rooij, Zoltán Kutalik, Abbas Dehghan, Barbara McKnight, Cornelia M. van Duijn, Alanna Morrison, Bruce M. Psaty, Eric Boerwinkle, Caroline S. Fox, Owen M. Woodward, Anna Köttgen
Published 2018-10-01

Phenome-wide association studies across large population cohorts support drug target validation

by Dorothée Diogo, Chao Tian, Christopher S. Franklin, Mervi Alanne-Kinnunen, Michael March, Chris C. A. Spencer, Ciara Vangjeli, Michael E. Weale, Hannele Mattsson, Elina Kilpeläinen, Patrick M. A. Sleiman, Dermot F. Reilly, Joshua McElwee, Joseph C. Maranville, Arnaub K. Chatterjee, Aman Bhandari, Khanh-Dung H. Nguyen, Karol Estrada, Mary-Pat Reeve, Janna Hutz, Nan Bing, Sally John, Daniel G. MacArthur, Veikko Salomaa, Samuli Ripatti, Hakon Hakonarson, Mark J. Daly, Aarno Palotie, David A. Hinds, Peter Donnelly, Caroline S. Fox, Aaron G. Day-Williams, Robert M. Plenge, Heiko Runz
Published 2018-10-01

Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.

by Carsten A Böger, Mathias Gorski, Man Li, Michael M Hoffmann, Chunmei Huang, Qiong Yang, Alexander Teumer, Vera Krane, Conall M O'Seaghdha, Zoltán Kutalik, H-Erich Wichmann, Thomas Haak, Eva Boes, Stefan Coassin, Josef Coresh, Barbara Kollerits, Margot Haun, Bernhard Paulweber, Anna Köttgen, Guo Li, Michael G Shlipak, Neil Powe, Shih-Jen Hwang, Abbas Dehghan, Fernando Rivadeneira, André Uitterlinden, Albert Hofman, Jacques S Beckmann, Bernhard K Krämer, Jacqueline Witteman, Murielle Bochud, David Siscovick, Rainer Rettig, Florian Kronenberg, Christoph Wanner, Ravi I Thadhani, Iris M Heid, Caroline S Fox, W H Kao, CKDGen Consortium
Published 2011-09-01

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts.

by Helen N Lyon, Valur Emilsson, Anke Hinney, Iris M Heid, Jessica Lasky-Su, Xiaofeng Zhu, Gudmar Thorleifsson, Steinunn Gunnarsdottir, G Bragi Walters, Unnur Thorsteinsdottir, Augustine Kong, Jeffrey Gulcher, Thuy Trang Nguyen, André Scherag, Arne Pfeufer, Thomas Meitinger, Günter Brönner, Winfried Rief, Manuel E Soto-Quiros, Lydiana Avila, Barbara Klanderman, Benjamin A Raby, Edwin K Silverman, Scott T Weiss, Nan Laird, Xiao Ding, Leif Groop, Tiinamaija Tuomi, Bo Isomaa, Kristina Bengtsson, Johannah L Butler, Richard S Cooper, Caroline S Fox, Christopher J O'Donnell, Caren Vollmert, Juan C Celedón, H Erich Wichmann, Johannes Hebebrand, Kari Stefansson, Christoph Lange, Joel N Hirschhorn
Published 2007-04-01

Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.

by Tamra E Meyer, Germaine C Verwoert, Shih-Jen Hwang, Nicole L Glazer, Albert V Smith, Frank J A van Rooij, Georg B Ehret, Eric Boerwinkle, Janine F Felix, Tennille S Leak, Tamara B Harris, Qiong Yang, Abbas Dehghan, Thor Aspelund, Ronit Katz, Georg Homuth, Thomas Kocher, Rainer Rettig, Janina S Ried, Christian Gieger, Hanna Prucha, Arne Pfeufer, Thomas Meitinger, Josef Coresh, Albert Hofman, Mark J Sarnak, Yii-Der Ida Chen, André G Uitterlinden, Aravinda Chakravarti, Bruce M Psaty, Cornelia M van Duijn, W H Linda Kao, Jacqueline C M Witteman, Vilmundur Gudnason, David S Siscovick, Caroline S Fox, Anna Köttgen, Genetic Factors for Osteoporosis Consortium, Meta Analysis of Glucose and Insulin Related Traits Consortium
Published 2010-08-01

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.

by Elizabeth K Speliotes, Laura M Yerges-Armstrong, Jun Wu, Ruben Hernaez, Lauren J Kim, Cameron D Palmer, Vilmundur Gudnason, Gudny Eiriksdottir, Melissa E Garcia, Lenore J Launer, Michael A Nalls, Jeanne M Clark, Braxton D Mitchell, Alan R Shuldiner, Johannah L Butler, Marta Tomas, Udo Hoffmann, Shih-Jen Hwang, Joseph M Massaro, Christopher J O'Donnell, Dushyant V Sahani, Veikko Salomaa, Eric E Schadt, Stephen M Schwartz, David S Siscovick, NASH CRN, GIANT Consortium, MAGIC Investigators, Benjamin F Voight, J Jeffrey Carr, Mary F Feitosa, Tamara B Harris, Caroline S Fox, Albert V Smith, W H Linda Kao, Joel N Hirschhorn, Ingrid B Borecki, GOLD Consortium
Published 2011-03-01

Genetic association for renal traits among participants of African ancestry reveals new loci for renal function.

by Ching-Ti Liu, Maija K Garnaas, Adrienne Tin, Anna Kottgen, Nora Franceschini, Carmen A Peralta, Ian H de Boer, Xiaoning Lu, Elizabeth Atkinson, Jingzhong Ding, Michael Nalls, Daniel Shriner, Josef Coresh, Abdullah Kutlar, Kirsten Bibbins-Domingo, David Siscovick, Ermeg Akylbekova, Sharon Wyatt, Brad Astor, Josef Mychaleckjy, Man Li, Muredach P Reilly, Raymond R Townsend, Adebowale Adeyemo, Alan B Zonderman, Mariza de Andrade, Stephen T Turner, Thomas H Mosley, Tamara B Harris, CKDGen Consortium, Charles N Rotimi, Yongmei Liu, Sharon L R Kardia, Michele K Evans, Michael G Shlipak, Holly Kramer, Michael F Flessner, Albert W Dreisbach, Wolfram Goessling, L Adrienne Cupples, W Linda Kao, Caroline S Fox
Published 2011-09-01