Footprints in the Sand: Deep Taxonomic Comparisons in Vertebrate Genomics to Unveil the Genetic Programs of Human Longevity

by Stephen Treaster, Stephen Treaster, David Karasik, David Karasik, Matthew P. Harris, Matthew P. Harris
Published 2021-06-01

Zebrafish models of sarcopenia

by Alon Daya, Rajashekar Donaka, David Karasik
Published 2020-03-01

Role of hydrolyzed collagen in bone regeneration of adult zebrafish

by Nili Vasserman, Chen Shochat Carvalho, David Karasik
Published 2020-10-01

Students as anatomy near-peer teachers: a double-edged sword for an ancient skill

by Nomy Dickman, Alon Barash, Shmuel Reis, David Karasik
Published 2017-09-01

Editorial: Recent Advances in the Genetics of Osteoporosis

by Jonathan H. Tobias, Jonathan H. Tobias, David Karasik
Published 2021-03-01

Screening of musculoskeletal GWAS-discovered lncRNAs in zebrafish

by Bodhisattwa Banerjee, Ines Fößl, Barbara Obermayer-Pietsch, David Karasik
Published 2020-10-01

The application of Lugol´s staining for microcomputerized tomografy to visualize and quantify muscles in zebrafish model

by Iryna Khrystoforova, Rajashekar Donaka, Chen Schochat-Carvalho, David Karasik
Published 2020-10-01

mRNA-lncRNA Co-Expression Network Analysis Reveals the Role of lncRNAs in Immune Dysfunction during Severe SARS-CoV-2 Infection

by Sumit Mukherjee, Bodhisattwa Banerjee, David Karasik, Milana Frenkel-Morgenstern
Published 2021-03-01

Leveraging data from bivariate genome-wide association meta-analysis to unravel novel pleitropic pathways of bone-muscle crosstalk

by Katerina Trajanoska, Niki L. Dimou, David Karasik, Fernando Rivadeneira, Gefos Consirtia
Published 2020-10-01

Lrp5 gene knockout causes craniofacial deformities and fractures in adult zebrafish

by Iryna Khrystoforova, Chen Shochat-Carvalho, Katherine C. Woronowicz, Matthew P. Harris, David Karasik
Published 2021-04-01

Membrane palmitoylated protein 7 (MPP7) and anaphase promoting complex subunit 1 (ANAPC1) associate with bone remodelling and osteoporosis

by Petra Malavašič, Ajda Ogrin, Iryna Khrystoforova, Einav Wircer, Chen Shochat, Janja Marc, David Karasik, Nika Lovšin
Published 2020-10-01

Evaluation of the long-term skeletal effect induced by teratogen 5-aza-2′deoxycytidine on offspring of high (C3H/HeJ) and low (C57BL/6J) bone mass phenotype mice

by Deepak Kumar Khajuria, Maria Raygorodskaya, Eugene Kobyliansky, Yankel Gabet, Sahar Hiram Bab, Chen Shochat, Arkady Torchinsky, David Karasik
Published 2018-06-01

Lrp5 mutant and crispant zebrafish faithfully model human osteoporosis, establishing the zebrafish as a platform for CRISPR-based functional screening of osteoporosis candidate gen...

by Jan Willem Bek, Chen Shochat, Adelbert De Clercq, Hanna De Saffel, Annekatrien Boel, Juriaan Metz, Frans Rodenburg, David Karasik, Andy Willaert, Paul Coucke
Published 2021-04-01

A whole genome sequencing study to identify novel genetic variants associated with lean mass: Multi-ethnic meta-analysis

by David Karasik, Zhang Xiaoyu, Su Kuan-Jui, Liu Ching-Ti, Xu Hanfei, Fu Mao, Wiggins Kerri, Hsu Yi-Hsiang, Yau Michelle, Crandall Carolyn, Mitchell Braxton, Jackson Rebecca, Montasser May, P. Kiel Douglas, Deng HongWen
Published 2021-04-01

The “GEnomics of Musculo Skeletal Traits TranslatiOnal NEtwork”: Origins, Rationale, Organization, and Prospects

by Fjorda Koromani, Fjorda Koromani, Fjorda Koromani, Nerea Alonso, Ines Alves, Maria Luisa Brandi, Ines Foessl, Melissa M. Formosa, Milana Frenkel Morgenstern, David Karasik, Mikhail Kolev, Outi Makitie, Outi Makitie, Outi Makitie, Evangelia Ntzani, Evangelia Ntzani, Barbara Obermayer Pietsch, Claes Ohlsson, Martina Rauner, Kent Soe, Kent Soe, Kent Soe, Ivan Soldatovic, Anna Teti, Amina Valjevac, Fernando Rivadeneira
Published 2021-08-01

Opportunities and Challenges in Functional Genomics Research in Osteoporosis: Report From a Workshop Held by the Causes Working Group of the Osteoporosis and Bone Research Academy...

by Jonathan H. Tobias, Jonathan H. Tobias, Emma L. Duncan, Erika Kague, Chrissy L. Hammond, Celia L. Gregson, Celia L. Gregson, Duncan Bassett, Graham R. Williams, Josine L. Min, Tom R. Gaunt, David Karasik, Claes Ohlsson, Fernando Rivadeneira, James R. Edwards, Fadil M. Hannan, John P. Kemp, John P. Kemp, Sophie J. Gilbert, Nerea Alonso, Neelam Hassan, Juliet E. Compston, Stuart H. Ralston
Published 2021-02-01

Novel BMD loci identified by whole genome sequencing and CRISPR editing in zebrafish: The NHLBI Trans-Omics for Precision Medicine (TOPMED) study

by Yi-Hsiang Hsu, Joyce W. Tang, Hanfei Xu, Cecily Choy, May Montasser, Carolyn Crandall, Ming-Ju Tsai, Mao Fu, Jeff R. O'Connell, James Perry, Shabnam Salimi, Elizabeth Streeten, Charles Farber, David Karasik, David M. Evans, Jonathan H. Tobias, Brent Richards, Ching-Ti Liu, Robert Wallace, John Blangero, Kerri Wiggins, Rebecca Jackson, Douglas Kiel, Braxton D. Mitchell, Ronald Y. Kwon
Published 2021-04-01

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.

by Yi-Hsiang Hsu, M Carola Zillikens, Scott G Wilson, Charles R Farber, Serkalem Demissie, Nicole Soranzo, Estelle N Bianchi, Elin Grundberg, Liming Liang, J Brent Richards, Karol Estrada, Yanhua Zhou, Atila van Nas, Miriam F Moffatt, Guangju Zhai, Albert Hofman, Joyce B van Meurs, Huibert A P Pols, Roger I Price, Olle Nilsson, Tomi Pastinen, L Adrienne Cupples, Aldons J Lusis, Eric E Schadt, Serge Ferrari, André G Uitterlinden, Fernando Rivadeneira, Timothy D Spector, David Karasik, Douglas P Kiel
Published 2010-06-01

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

by Carolina Medina-Gomez, John P. Kemp, Niki L. Dimou, Eskil Kreiner, Alessandra Chesi, Babette S. Zemel, Klaus Bønnelykke, Cindy G. Boer, Tarunveer S. Ahluwalia, Hans Bisgaard, Evangelos Evangelou, Denise H. M. Heppe, Lynda F. Bonewald, Jeffrey P. Gorski, Mohsen Ghanbari, Serkalem Demissie, Gustavo Duque, Matthew T. Maurano, Douglas P. Kiel, Yi-Hsiang Hsu, Bram C.J. van der Eerden, Cheryl Ackert-Bicknell, Sjur Reppe, Kaare M. Gautvik, Truls Raastad, David Karasik, Jeroen van de Peppel, Vincent W. V. Jaddoe, André G. Uitterlinden, Jonathan H. Tobias, Struan F.A. Grant, Pantelis G. Bagos, David M. Evans, Fernando Rivadeneira
Published 2017-07-01

Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program.

by Chloé Sarnowski, Han Chen, Mary L Biggs, Sylvia Wassertheil-Smoller, Jan Bressler, Marguerite R Irvin, Kathleen A Ryan, David Karasik, Donna K Arnett, L Adrienne Cupples, David W Fardo, Stephanie M Gogarten, Benjamin D Heavner, Deepti Jain, Hyun Min Kang, Charles Kooperberg, Arch G Mainous, Braxton D Mitchell, Alanna C Morrison, Jeffrey R O'Connell, Bruce M Psaty, Kenneth Rice, Albert V Smith, Ramachandran S Vasan, B Gwen Windham, Douglas P Kiel, Joanne M Murabito, Kathryn L Lunetta, TOPMed Longevity and Healthy Aging Working Group, from the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium
Published 2021-01-01