Application of ancestry informative markers to association studies in European Americans.

by Michael F Seldin, Alkes L Price
Published 2008-01-01

Population structure and eigenanalysis.

by Nick Patterson, Alkes L Price, David Reich
Published 2006-12-01

Improving the informativeness of Mendelian disease-derived pathogenicity scores for common disease

by Samuel S. Kim, Kushal K. Dey, Omer Weissbrod, Carla Márquez-Luna, Steven Gazal, Alkes L. Price
Published 2020-12-01

Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals.

by Alkes L Price, Agnar Helgason, Gudmar Thorleifsson, Steven A McCarroll, Augustine Kong, Kari Stefansson
Published 2011-02-01

Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits.

by Noah Zaitlen, Peter Kraft, Nick Patterson, Bogdan Pasaniuc, Gaurav Bhatia, Samuela Pollack, Alkes L Price
Published 2013-05-01

Effects of cis and trans genetic ancestry on gene expression in African Americans.

by Alkes L Price, Nick Patterson, Dustin C Hancks, Simon Myers, David Reich, Vivian G Cheung, Richard S Spielman
Published 2008-12-01

GBAT: a gene-based association test for robust detection of trans-gene regulation

by Xuanyao Liu, Joel A. Mefford, Andrew Dahl, Yuan He, Meena Subramaniam, Alexis Battle, Alkes L. Price, Noah Zaitlen
Published 2020-08-01

Integrating functional data to prioritize causal variants in statistical fine-mapping studies.

by Gleb Kichaev, Wen-Yun Yang, Sara Lindstrom, Farhad Hormozdiari, Eleazar Eskin, Alkes L Price, Peter Kraft, Bogdan Pasaniuc
Published 2014-10-01

Evaluating the informativeness of deep learning annotations for human complex diseases

by Kushal K. Dey, Bryce van de Geijn, Samuel Sungil Kim, Farhad Hormozdiari, David R. Kelley, Alkes L. Price
Published 2020-09-01

The impact of divergence time on the nature of population structure: an example from Iceland.

by Alkes L Price, Agnar Helgason, Snaebjorn Palsson, Hreinn Stefansson, David St Clair, Ole A Andreassen, David Reich, Augustine Kong, Kari Stefansson
Published 2009-06-01

The history of African gene flow into Southern Europeans, Levantines, and Jews.

by Priya Moorjani, Nick Patterson, Joel N Hirschhorn, Alon Keinan, Li Hao, Gil Atzmon, Edward Burns, Harry Ostrer, Alkes L Price, David Reich
Published 2011-04-01

Sensitive detection of chromosomal segments of distinct ancestry in admixed populations.

by Alkes L Price, Arti Tandon, Nick Patterson, Kathleen C Barnes, Nicholas Rafaels, Ingo Ruczinski, Terri H Beaty, Rasika Mathias, David Reich, Simon Myers
Published 2009-06-01

Functional disease architectures reveal unique biological role of transposable elements

by Farhad Hormozdiari, Bryce van de Geijn, Joseph Nasser, Omer Weissbrod, Steven Gazal, Chelsea J. -T. Ju, Luke O’ Connor, Margaux L. A. Hujoel, Jesse Engreitz, Fereydoun Hormozdiari, Alkes L. Price
Published 2019-09-01

Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection

by Armin P. Schoech, Daniel M. Jordan, Po-Ru Loh, Steven Gazal, Luke J. O’Connor, Daniel J. Balick, Pier F. Palamara, Hilary K. Finucane, Shamil R. Sunyaev, Alkes L. Price
Published 2019-02-01

Quantifying missing heritability at known GWAS loci.

by Alexander Gusev, Gaurav Bhatia, Noah Zaitlen, Bjarni J Vilhjalmsson, Dorothée Diogo, Eli A Stahl, Peter K Gregersen, Jane Worthington, Lars Klareskog, Soumya Raychaudhuri, Robert M Plenge, Bogdan Pasaniuc, Alkes L Price
Published 2013-01-01

Population-specific causal disease effect sizes in functionally important regions impacted by selection

by Huwenbo Shi, Steven Gazal, Masahiro Kanai, Evan M. Koch, Armin P. Schoech, Katherine M. Siewert, Samuel S. Kim, Yang Luo, Tiffany Amariuta, Hailiang Huang, Yukinori Okada, Soumya Raychaudhuri, Shamil R. Sunyaev, Alkes L. Price
Published 2021-02-01

Discerning the ancestry of European Americans in genetic association studies.

by Alkes L Price, Johannah Butler, Nick Patterson, Cristian Capelli, Vincenzo L Pascali, Francesca Scarnicci, Andres Ruiz-Linares, Leif Groop, Angelica A Saetta, Penelope Korkolopoulou, Uri Seligsohn, Alicja Waliszewska, Christine Schirmer, Kristin Ardlie, Alexis Ramos, James Nemesh, Lori Arbeitman, David B Goldstein, David Reich, Joel N Hirschhorn
Published 2008-01-01

Informed conditioning on clinical covariates increases power in case-control association studies.

by Noah Zaitlen, Sara Lindström, Bogdan Pasaniuc, Marilyn Cornelis, Giulio Genovese, Samuela Pollack, Anne Barton, Heike Bickeböller, Donald W Bowden, Steve Eyre, Barry I Freedman, David J Friedman, John K Field, Leif Groop, Aage Haugen, Joachim Heinrich, Brian E Henderson, Pamela J Hicks, Lynne J Hocking, Laurence N Kolonel, Maria Teresa Landi, Carl D Langefeld, Loic Le Marchand, Michael Meister, Ann W Morgan, Olaide Y Raji, Angela Risch, Albert Rosenberger, David Scherf, Sophia Steer, Martin Walshaw, Kevin M Waters, Anthony G Wilson, Paul Wordsworth, Shanbeh Zienolddiny, Eric Tchetgen Tchetgen, Christopher Haiman, David J Hunter, Robert M Plenge, Jane Worthington, David C Christiani, Debra A Schaumberg, Daniel I Chasman, David Altshuler, Benjamin Voight, Peter Kraft, Nick Patterson, Alkes L Price
Published 2012-01-01

Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium.

by Bogdan Pasaniuc, Noah Zaitlen, Guillaume Lettre, Gary K Chen, Arti Tandon, W H Linda Kao, Ingo Ruczinski, Myriam Fornage, David S Siscovick, Xiaofeng Zhu, Emma Larkin, Leslie A Lange, L Adrienne Cupples, Qiong Yang, Ermeg L Akylbekova, Solomon K Musani, Jasmin Divers, Joe Mychaleckyj, Mingyao Li, George J Papanicolaou, Robert C Millikan, Christine B Ambrosone, Esther M John, Leslie Bernstein, Wei Zheng, Jennifer J Hu, Regina G Ziegler, Sarah J Nyante, Elisa V Bandera, Sue A Ingles, Michael F Press, Stephen J Chanock, Sandra L Deming, Jorge L Rodriguez-Gil, Cameron D Palmer, Sarah Buxbaum, Lynette Ekunwe, Joel N Hirschhorn, Brian E Henderson, Simon Myers, Christopher A Haiman, David Reich, Nick Patterson, James G Wilson, Alkes L Price
Published 2011-04-01

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies.

by Brendan J Keating, Sam Tischfield, Sarah S Murray, Tushar Bhangale, Thomas S Price, Joseph T Glessner, Luana Galver, Jeffrey C Barrett, Struan F A Grant, Deborah N Farlow, Hareesh R Chandrupatla, Mark Hansen, Saad Ajmal, George J Papanicolaou, Yiran Guo, Mingyao Li, Stephanie Derohannessian, Paul I W de Bakker, Swneke D Bailey, Alexandre Montpetit, Andrew C Edmondson, Kent Taylor, Xiaowu Gai, Susanna S Wang, Myriam Fornage, Tamim Shaikh, Leif Groop, Michael Boehnke, Alistair S Hall, Andrew T Hattersley, Edward Frackelton, Nick Patterson, Charleston W K Chiang, Cecelia E Kim, Richard R Fabsitz, Willem Ouwehand, Alkes L Price, Patricia Munroe, Mark Caulfield, Thomas Drake, Eric Boerwinkle, David Reich, A Stephen Whitehead, Thomas P Cappola, Nilesh J Samani, A Jake Lusis, Eric Schadt, James G Wilson, Wolfgang Koenig, Mark I McCarthy, Sekar Kathiresan, Stacey B Gabriel, Hakon Hakonarson, Sonia S Anand, Muredach Reilly, James C Engert, Deborah A Nickerson, Daniel J Rader, Joel N Hirschhorn, Garret A Fitzgerald
Published 2008-01-01