Optimisation of an Advanced Oxidation Protein Products Assay: Its Application to Studies of Oxidative Stress in Diabetes Mellitus

by Emma L. Taylor, Kenneth R. Armstrong, David Perrett, Andrew T. Hattersley, Paul G. Winyard
Published 2015-01-01

Understanding the manifestation of diabetes in sub Saharan Africa to inform therapeutic approaches and preventive strategies: a narrative review

by Davis Kibirige, William Lumu, Angus G. Jones, Liam Smeeth, Andrew T. Hattersley, Moffat J. Nyirenda
Published 2019-02-01

Identifying good responders to glucose lowering therapy in type 2 diabetes: implications for stratified medicine.

by Angus G Jones, Beverley M Shields, Christopher J Hyde, William E Henley, Andrew T Hattersley
Published 2014-01-01

In celebration of a century with insulin – Update of insulin gene mutations in diabetes

by Julie Støy, Elisa De Franco, Honggang Ye, Soo-Young Park, Graeme I. Bell, Andrew T. Hattersley
Published 2021-10-01

Should Studies of Diabetes Treatment Stratification Correct for Baseline HbA1c?

by Angus G Jones, Mike Lonergan, William E Henley, Ewan R Pearson, Andrew T Hattersley, Beverley M Shields
Published 2016-01-01

Lower Circulating B12 Is Associated with Higher Obesity and Insulin Resistance during Pregnancy in a Non-Diabetic White British Population.

by Bridget Ann Knight, Beverley M Shields, Adam Brook, Anita Hill, Dattatray S Bhat, Andrew T Hattersley, Chittaranjan S Yajnik
Published 2015-01-01

Gain-of-function mutations in the K(ATP) channel (KCNJ11) impair coordinated hand-eye tracking.

by James S McTaggart, Ned Jenkinson, John-Stuart Brittain, Siri A W Greeley, Andrew T Hattersley, Frances M Ashcroft
Published 2013-01-01

Use of HbA1c in the identification of patients with hyperglycaemia caused by a glucokinase mutation: observational case control studies.

by Anna M Steele, Kirsty J Wensley, Sian Ellard, Rinki Murphy, Maggie Shepherd, Kevin Colclough, Andrew T Hattersley, Beverley M Shields
Published 2013-01-01

What to do with diabetes therapies when HbA1c lowering is inadequate: add, switch, or continue? A MASTERMIND study

by Andrew P. McGovern, John M. Dennis, Beverley M. Shields, Andrew T. Hattersley, Ewan R. Pearson, Angus G. Jones, On behalf of the MASTERMIND Consortium
Published 2019-04-01

Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to type 2 diabetes.

by Bahram Jafar-Mohammadi, Christopher J Groves, Katharine R Owen, Timothy M Frayling, Andrew T Hattersley, Mark I McCarthy, Anna L Gloyn
Published 2009-08-01

Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A gene.

by Ewan R Pearson, Sylvia F Boj, Anna M Steele, Timothy Barrett, Karen Stals, Julian P Shield, Sian Ellard, Jorge Ferrer, Andrew T Hattersley
Published 2007-04-01

Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable.

by Debbie A Lawlor, Nicholas J Timpson, Roger M Harbord, Sam Leary, Andy Ness, Mark I McCarthy, Timothy M Frayling, Andrew T Hattersley, George Davey Smith
Published 2008-03-01

EDTA improves stability of whole blood C-peptide and insulin to over 24 hours at room temperature.

by Timothy J McDonald, Mandy H Perry, Roy W A Peake, Nicola J Pullan, John O'Connor, Beverley M Shields, Beatrice A Knight, Andrew T Hattersley
Published 2012-01-01

Dietary energy density affects fat mass in early adolescence and is not modified by FTO variants.

by Laura Johnson, Cornelia H M van Jaarsveld, Pauline M Emmett, Imogen S Rogers, Andy R Ness, Andrew T Hattersley, Nicholas J Timpson, George Davey Smith, Susan A Jebb
Published 2009-01-01

Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene

by Ildem Akerman, Miguel Angel Maestro, Elisa De Franco, Vanessa Grau, Sarah Flanagan, Javier García-Hurtado, Gerhard Mittler, Philippe Ravassard, Lorenzo Piemonti, Sian Ellard, Andrew T. Hattersley, Jorge Ferrer
Published 2021-04-01

Choice of HbA1c threshold for identifying individuals at high risk of type 2 diabetes and implications for diabetes prevention programmes: a cohort study

by Lauren R. Rodgers, Anita V. Hill, John M. Dennis, Zoe Craig, Benedict May, Andrew T. Hattersley, Timothy J. McDonald, Rob C. Andrews, Angus Jones, Beverley M. Shields
Published 2021-08-01

Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis.

by William D Thompson, Jessica Tyrrell, Maria-Carolina Borges, Robin N Beaumont, Bridget A Knight, Andrew R Wood, Susan M Ring, Andrew T Hattersley, Rachel M Freathy, Debbie A Lawlor
Published 2019-06-01

Combining information from common type 2 diabetes risk polymorphisms improves disease prediction.

by Michael N Weedon, Mark I McCarthy, Graham Hitman, Mark Walker, Christopher J Groves, Eleftheria Zeggini, N William Rayner, Beverley Shields, Katharine R Owen, Andrew T Hattersley, Timothy M Frayling
Published 2006-10-01

GATA6 Cooperates with EOMES/SMAD2/3 to Deploy the Gene Regulatory Network Governing Human Definitive Endoderm and Pancreas Formation

by Crystal Y. Chia, Pedro Madrigal, Simon L.I.J. Denil, Iker Martinez, Jose Garcia-Bernardo, Ranna El-Khairi, Mariya Chhatriwala, Maggie H. Shepherd, Andrew T. Hattersley, N. Ray Dunn, Ludovic Vallier
Published 2019-01-01

All thresholds of maternal hyperglycaemia from the WHO 2013 criteria for gestational diabetes identify women with a higher genetic risk for type 2 diabetes [version 3; peer review:...

by Alice E. Hughes, M. Geoffrey Hayes, Aoife M. Egan, Kashyap A. Patel, Denise M. Scholtens, Lynn P. Lowe, William L. Lowe Jr, Fidelma P. Dunne, Andrew T. Hattersley, Rachel M. Freathy
Published 2021-03-01