Phenotype prediction using regularized regression on genetic data in the DREAM5 Systems Genetics B Challenge.

by Po-Ru Loh, George Tucker, Bonnie Berger
Published 2011-01-01

Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes.

by Mark Lipson, Po-Ru Loh, Sriram Sankararaman, Nick Patterson, Bonnie Berger, David Reich
Published 2015-11-01

Efficient cross-trait penalized regression increases prediction accuracy in large cohorts using secondary phenotypes

by Wonil Chung, Jun Chen, Constance Turman, Sara Lindstrom, Zhaozhong Zhu, Po-Ru Loh, Peter Kraft, Liming Liang
Published 2019-02-01

Genetically predicted telomere length is associated with clonal somatic copy number alterations in peripheral leukocytes.

by Derek W Brown, Shu-Hong Lin, Po-Ru Loh, Stephen J Chanock, Sharon A Savage, Mitchell J Machiela
Published 2020-10-01

Reconstructing Roma history from genome-wide data.

by Priya Moorjani, Nick Patterson, Po-Ru Loh, Mark Lipson, Péter Kisfali, Bela I Melegh, Michael Bonin, Ludevít Kádaši, Olaf Rieß, Bonnie Berger, David Reich, Béla Melegh
Published 2013-01-01

Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection

by Armin P. Schoech, Daniel M. Jordan, Po-Ru Loh, Steven Gazal, Luke J. O’Connor, Daniel J. Balick, Pier F. Palamara, Hilary K. Finucane, Shamil R. Sunyaev, Alkes L. Price
Published 2019-02-01

GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation

by Chikashi Terao, Yukihide Momozawa, Kazuyoshi Ishigaki, Eiryo Kawakami, Masato Akiyama, Po-Ru Loh, Giulio Genovese, Hiroki Sugishita, Tazro Ohta, Makoto Hirata, John R. B. Perry, Koichi Matsuda, Yoshinori Murakami, Michiaki Kubo, Yoichiro Kamatani
Published 2019-10-01

GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health

by Yajie Zhao, Stasa Stankovic, Mine Koprulu, Eleanor Wheeler, Felix R. Day, Hana Lango Allen, Nicola D. Kerrison, Maik Pietzner, Po-Ru Loh, Nicholas J. Wareham, Claudia Langenberg, Ken K. Ong, John R. B. Perry
Published 2021-07-01

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

by Sara M. Willems, Daniel J. Wright, Felix R. Day, Katerina Trajanoska, Peter K. Joshi, John A. Morris, Amy M. Matteini, Fleur C. Garton, Niels Grarup, Nikolay Oskolkov, Anbupalam Thalamuthu, Massimo Mangino, Jun Liu, Ayse Demirkan, Monkol Lek, Liwen Xu, Guan Wang, Christopher Oldmeadow, Kyle J. Gaulton, Luca A. Lotta, Eri Miyamoto-Mikami, Manuel A. Rivas, Tom White, Po-Ru Loh, Mette Aadahl, Najaf Amin, John R. Attia, Krista Austin, Beben Benyamin, Søren Brage, Yu-Ching Cheng, Paweł Cięszczyk, Wim Derave, Karl-Fredrik Eriksson, Nir Eynon, Allan Linneberg, Alejandro Lucia, Myosotis Massidda, Braxton D. Mitchell, Motohiko Miyachi, Haruka Murakami, Sandosh Padmanabhan, Ashutosh Pandey, Ioannis Papadimitriou, Deepak K. Rajpal, Craig Sale, Theresia M. Schnurr, Francesco Sessa, Nick Shrine, Martin D. Tobin, Ian Varley, Louise V. Wain, Naomi R. Wray, Cecilia M. Lindgren, Daniel G. MacArthur, Dawn M. Waterworth, Mark I. McCarthy, Oluf Pedersen, Kay-Tee Khaw, Douglas P. Kiel, GEFOS Any-Type of Fracture Consortium, Yannis Pitsiladis, Noriyuki Fuku, Paul W. Franks, Kathryn N. North, Cornelia M. van Duijn, Karen A. Mather, Torben Hansen, Ola Hansson, Tim Spector, Joanne M. Murabito, J. Brent Richards, Fernando Rivadeneira, Claudia Langenberg, John R. B. Perry, Nick J. Wareham, Robert A. Scott
Published 2017-07-01