Tissue-Specific Enrichment of Lymphoma Risk Loci in Regulatory Elements.

by James E Hayes, Gosia Trynka, Joseph Vijai, Kenneth Offit, Soumya Raychaudhuri, Robert J Klein
Published 2015-01-01

Accurate imputation of human leukocyte antigens with CookHLA

by Seungho Cook, Wanson Choi, Hyunjoon Lim, Yang Luo, Kunhee Kim, Xiaoming Jia, Soumya Raychaudhuri, Buhm Han
Published 2021-02-01

Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease.

by Hong-Hee Won, Pradeep Natarajan, Amanda Dobbyn, Daniel M Jordan, Panos Roussos, Kasper Lage, Soumya Raychaudhuri, Eli Stahl, Ron Do
Published 2015-10-01

Efficient and precise single-cell reference atlas mapping with Symphony

by Joyce B. Kang, Aparna Nathan, Kathryn Weinand, Fan Zhang, Nghia Millard, Laurie Rumker, D. Branch Moody, Ilya Korsunsky, Soumya Raychaudhuri
Published 2021-10-01

Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function.

by Soumya Raychaudhuri, Joshua M Korn, Steven A McCarroll, International Schizophrenia Consortium, David Altshuler, Pamela Sklar, Shaun Purcell, Mark J Daly
Published 2010-09-01

Imputing amino acid polymorphisms in human leukocyte antigens.

by Xiaoming Jia, Buhm Han, Suna Onengut-Gumuscu, Wei-Min Chen, Patrick J Concannon, Stephen S Rich, Soumya Raychaudhuri, Paul I W de Bakker
Published 2013-01-01

Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.

by Elizabeth J Rossin, Kasper Lage, Soumya Raychaudhuri, Ramnik J Xavier, Diana Tatar, Yair Benita, International Inflammatory Bowel Disease Genetics Constortium, Chris Cotsapas, Mark J Daly
Published 2011-01-01

Quantifying missing heritability at known GWAS loci.

by Alexander Gusev, Gaurav Bhatia, Noah Zaitlen, Bjarni J Vilhjalmsson, Dorothée Diogo, Eli A Stahl, Peter K Gregersen, Jane Worthington, Lars Klareskog, Soumya Raychaudhuri, Robert M Plenge, Bogdan Pasaniuc, Alkes L Price
Published 2013-01-01

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.

by Soumya Raychaudhuri, Robert M Plenge, Elizabeth J Rossin, Aylwin C Y Ng, International Schizophrenia Consortium, Shaun M Purcell, Pamela Sklar, Edward M Scolnick, Ramnik J Xavier, David Altshuler, Mark J Daly
Published 2009-06-01

IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation

by Fan Zhang, Joseph R. Mears, Lorien Shakib, Jessica I. Beynor, Sara Shanaj, Ilya Korsunsky, Aparna Nathan, Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium, Laura T. Donlin, Soumya Raychaudhuri
Published 2021-04-01

Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions

by Maria Gutierrez-Arcelus, Nikola Teslovich, Alex R. Mola, Rafael B. Polidoro, Aparna Nathan, Hyun Kim, Susan Hannes, Kamil Slowikowski, Gerald F. M. Watts, Ilya Korsunsky, Michael B. Brenner, Soumya Raychaudhuri, Patrick J. Brennan
Published 2019-02-01

Population-specific causal disease effect sizes in functionally important regions impacted by selection

by Huwenbo Shi, Steven Gazal, Masahiro Kanai, Evan M. Koch, Armin P. Schoech, Katherine M. Siewert, Samuel S. Kim, Yang Luo, Tiffany Amariuta, Hailiang Huang, Yukinori Okada, Soumya Raychaudhuri, Shamil R. Sunyaev, Alkes L. Price
Published 2021-02-01

Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells.

by Xinli Hu, Hyun Kim, Towfique Raj, Patrick J Brennan, Gosia Trynka, Nikola Teslovich, Kamil Slowikowski, Wei-Min Chen, Suna Onengut, Clare Baecher-Allan, Philip L De Jager, Stephen S Rich, Barbara E Stranger, Michael B Brenner, Soumya Raychaudhuri
Published 2014-06-01

FcγR engagement reprograms neutrophils into antigen cross-presenting cells that elicit acquired anti-tumor immunity

by Vijayashree Mysore, Xavier Cullere, Joseph Mears, Florencia Rosetti, Koshu Okubo, Pei X. Liew, Fan Zhang, Iris Madera-Salcedo, Frank Rosenbauer, Richard M. Stone, Jon C. Aster, Ulrich H. von Andrian, Andrew H. Lichtman, Soumya Raychaudhuri, Tanya N. Mayadas
Published 2021-08-01

Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial

by Emma E. Davenport, Tiffany Amariuta, Maria Gutierrez-Arcelus, Kamil Slowikowski, Harm-Jan Westra, Yang Luo, Ciyue Shen, Deepak A. Rao, Ying Zhang, Stephen Pearson, David von Schack, Jean S. Beebe, Nan Bing, Sally John, Michael S. Vincent, Baohong Zhang, Soumya Raychaudhuri
Published 2018-10-01

Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians

by Yang Luo, Sara Suliman, Samira Asgari, Tiffany Amariuta, Yuriy Baglaenko, Marta Martínez-Bonet, Kazuyoshi Ishigaki, Maria Gutierrez-Arcelus, Roger Calderon, Leonid Lecca, Segundo R. León, Judith Jimenez, Rosa Yataco, Carmen Contreras, Jerome T. Galea, Mercedes Becerra, Sergey Nejentsev, Peter A. Nigrovic, D. Branch Moody, Megan B. Murray, Soumya Raychaudhuri
Published 2019-08-01

Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations

by Ana Márquez, Martin Kerick, Alexandra Zhernakova, Javier Gutierrez-Achury, Wei-Min Chen, Suna Onengut-Gumuscu, Isidoro González-Álvaro, Luis Rodriguez-Rodriguez, Raquel Rios-Fernández, Miguel A. González-Gay, Coeliac Disease Immunochip Consortium, Rheumatoid Arthritis Consortium International for Immunochip (RACI), International Scleroderma Group, Type 1 Diabetes Genetics Consortium, Maureen D. Mayes, Soumya Raychaudhuri, Stephen S. Rich, Cisca Wijmenga, Javier Martín
Published 2018-12-01

A Role for Noncoding Variation in Schizophrenia

by Panos Roussos, Amanda C. Mitchell, Georgios Voloudakis, John F. Fullard, Venu M. Pothula, Jonathan Tsang, Eli A. Stahl, Anastasios Georgakopoulos, Douglas M. Ruderfer, Alexander Charney, Yukinori Okada, Katherine A. Siminovitch, Jane Worthington, Leonid Padyukov, Lars Klareskog, Peter K. Gregersen, Robert M. Plenge, Soumya Raychaudhuri, Menachem Fromer, Shaun M. Purcell, Kristen J. Brennand, Nikolaos K. Robakis, Eric E. Schadt, Schahram Akbarian, Pamela Sklar
Published 2014-11-01

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

by Fumitaka Mizoguchi, Kamil Slowikowski, Kevin Wei, Jennifer L. Marshall, Deepak A. Rao, Sook Kyung Chang, Hung N. Nguyen, Erika H. Noss, Jason D. Turner, Brandon E. Earp, Philip E. Blazar, John Wright, Barry P. Simmons, Laura T. Donlin, George D. Kalliolias, Susan M. Goodman, Vivian P. Bykerk, Lionel B. Ivashkiv, James A. Lederer, Nir Hacohen, Peter A. Nigrovic, Andrew Filer, Christopher D. Buckley, Soumya Raychaudhuri, Michael B. Brenner
Published 2018-02-01

Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway.

by Gang Li, Dorothée Diogo, Di Wu, Jim Spoonamore, Vlado Dancik, Lude Franke, Fina Kurreeman, Elizabeth J Rossin, Grant Duclos, Cathy Hartland, Xuezhong Zhou, Kejie Li, Jun Liu, Philip L De Jager, Katherine A Siminovitch, Alexandra Zhernakova, Soumya Raychaudhuri, John Bowes, Steve Eyre, Leonid Padyukov, Peter K Gregersen, Jane Worthington, Rheumatoid Arthritis Consortium International (RACI), Namrata Gupta, Paul A Clemons, Eli Stahl, Nicola Tolliday, Robert M Plenge
Published 2013-05-01