Multiethnic genetic association studies improve power for locus discovery.

by Sara L Pulit, Benjamin F Voight, Paul I W de Bakker
Published 2010-09-01

Association Claims in the Sequencing Era

by Sara L. Pulit, Maarten Leusink, Androniki Menelaou, Paul I. W. de Bakker
Published 2014-03-01

Extensive Association of Common Disease Variants with Regulatory Sequence.

by Michal Mokry, Magdalena Harakalova, Folkert W Asselbergs, Paul I W de Bakker, Edward E S Nieuwenhuis
Published 2016-01-01

No Additional Prognostic Value of Genetic Information in the Prediction of Vascular Events after Cerebral Ischemia of Arterial Origin: The PROMISe Study.

by Sefanja Achterberg, L Jaap Kappelle, Paul I W de Bakker, Matthew Traylor, Ale Algra, SMART Study Group and the METASTROKE Consortium
Published 2015-01-01

Imputing amino acid polymorphisms in human leukocyte antigens.

by Xiaoming Jia, Buhm Han, Suna Onengut-Gumuscu, Wei-Min Chen, Patrick J Concannon, Stephen S Rich, Soumya Raychaudhuri, Paul I W de Bakker
Published 2013-01-01

IL28B alleles exert an additive dose effect when applied to HCV-HIV coinfected persons undergoing peginterferon and ribavirin therapy.

by Barham K Abu Dayyeh, Namrata Gupta, Kenneth E Sherman, Paul I W de Bakker, Raymond T Chung, Aids Clinical Trials Group A5178 Study Team
Published 2011-01-01

Rs964184 (APOA5-A4-C3-A1) is related to elevated plasma triglyceride levels, but not to an increased risk for vascular events in patients with clinically manifest vascular disease.

by Anton P van de Woestijne, Yolanda van der Graaf, Paul I W de Bakker, Folkert W Asselbergs, Wilko Spiering, Frank L J Visseren, SMART Study Group
Published 2014-01-01

Correction: Effective Detection of Human Leukocyte Antigen Risk Alleles in Celiac Disease Using Tag Single Nucleotide Polymorphisms

by Alienke J. Monsuur, Paul I. W. de Bakker, Alexandra Zhernakova, Dalila Pinto, Willem Verduijn, Jihane Romanos, Renata Auricchio, Ana Lopez, David A. van Heel, J. Bart A Crusius, Cisca Wijmenga
Published 2009-01-01

Effective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphisms.

by Alienke J Monsuur, Paul I W de Bakker, Alexandra Zhernakova, Dalila Pinto, Willem Verduijn, Jihane Romanos, Renata Auricchio, Ana Lopez, David A van Heel, J Bart A Crusius, Cisca Wijmenga
Published 2008-01-01

Correction: Effective Detection of Human Leukocyte Antigen Risk Alleles in Celiac Disease Using Tag Single Nucleotide Polymorphisms.

by Alienke J. Monsuur, Paul I. W. de Bakker, Alexandra Zhernakova, Dalila Pinto, Willem Verduijn, Jihane Romanos, Renata Auricchio, Ana Lopez, David A. van Heel, J. Bart A Crusius, Cisca Wijmenga
Published 2009-01-01

Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction.

by Paul L Klarenbeek, Marieke E Doorenspleet, Rebecca E E Esveldt, Barbera D C van Schaik, Neubury Lardy, Antoine H C van Kampen, Paul P Tak, Robert M Plenge, Frank Baas, Paul I W de Bakker, Niek de Vries
Published 2015-01-01

Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency.

by Adam Kiezun, Sara L Pulit, Laurent C Francioli, Freerk van Dijk, Morris Swertz, Dorret I Boomsma, Cornelia M van Duijn, P Eline Slagboom, G J B van Ommen, Cisca Wijmenga, Genome of the Netherlands Consortium, Paul I W de Bakker, Shamil R Sunyaev
Published 2013-01-01

Genetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program.

by Toni I Pollin, Tamara Isakova, Kathleen A Jablonski, Paul I W de Bakker, Andrew Taylor, Jarred McAteer, Qing Pan, Edward S Horton, Linda M Delahanty, David Altshuler, Alan R Shuldiner, Ronald B Goldberg, Jose C Florez, Paul W Franks, Diabetes Prevention Program Research Group
Published 2012-01-01

Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects.

by Nikolaos A Patsopoulos, Lisa F Barcellos, Rogier Q Hintzen, Catherine Schaefer, Cornelia M van Duijn, Janelle A Noble, Towfique Raj, IMSGC, ANZgene, Pierre-Antoine Gourraud, Barbara E Stranger, Jorge Oksenberg, Tomas Olsson, Bruce V Taylor, Stephen Sawcer, David A Hafler, Mary Carrington, Philip L De Jager, Paul I W de Bakker
Published 2013-11-01

Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.

by Michael Inouye, Samuli Ripatti, Johannes Kettunen, Leo-Pekka Lyytikäinen, Niku Oksala, Pirkka-Pekka Laurila, Antti J Kangas, Pasi Soininen, Markku J Savolainen, Jorma Viikari, Mika Kähönen, Markus Perola, Veikko Salomaa, Olli Raitakari, Terho Lehtimäki, Marja-Riitta Taskinen, Marjo-Riitta Järvelin, Mika Ala-Korpela, Aarno Palotie, Paul I W de Bakker
Published 2012-01-01

A high-quality human reference panel reveals the complexity and distribution of genomic structural variants

by Jayne Y. Hehir-Kwa, Tobias Marschall, Wigard P. Kloosterman, Laurent C. Francioli, Jasmijn A. Baaijens, Louis J. Dijkstra, Abdel Abdellaoui, Vyacheslav Koval, Djie Tjwan Thung, René Wardenaar, Ivo Renkens, Bradley P. Coe, Patrick Deelen, Joep de Ligt, Eric-Wubbo Lameijer, Freerk van Dijk, Fereydoun Hormozdiari, The Genome of the Netherlands Consortium, André G. Uitterlinden, Cornelia M. van Duijn, Evan E. Eichler, Paul I. W. de Bakker, Morris A. Swertz, Cisca Wijmenga, Gert-Jan B. van Ommen, P. Eline Slagboom, Dorret I. Boomsma, Alexander Schönhuth, Kai Ye, Victor Guryev
Published 2016-10-01

High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms.

by Mitja I Kurki, Emília Ilona Gaál, Johannes Kettunen, Tuuli Lappalainen, Androniki Menelaou, Verneri Anttila, Femke N G van 't Hof, Mikael von Und Zu Fraunberg, Seppo Helisalmi, Mikko Hiltunen, Hanna Lehto, Aki Laakso, Riku Kivisaari, Timo Koivisto, Antti Ronkainen, Jaakko Rinne, Lambertus A L Kiemeney, Sita H Vermeulen, Mari A Kaunisto, Johan G Eriksson, Arpo Aromaa, Markus Perola, Terho Lehtimäki, Olli T Raitakari, Veikko Salomaa, Murat Gunel, Emmanouil T Dermitzakis, Ynte M Ruigrok, Gabriel J E Rinkel, Mika Niemelä, Juha Hernesniemi, Samuli Ripatti, Paul I W de Bakker, Aarno Palotie, Juha E Jääskeläinen
Published 2014-01-01

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.

by Alexandra Zhernakova, Eli A Stahl, Gosia Trynka, Soumya Raychaudhuri, Eleanora A Festen, Lude Franke, Harm-Jan Westra, Rudolf S N Fehrmann, Fina A S Kurreeman, Brian Thomson, Namrata Gupta, Jihane Romanos, Ross McManus, Anthony W Ryan, Graham Turner, Elisabeth Brouwer, Marcel D Posthumus, Elaine F Remmers, Francesca Tucci, Rene Toes, Elvira Grandone, Maria Cristina Mazzilli, Anna Rybak, Bozena Cukrowska, Marieke J H Coenen, Timothy R D J Radstake, Piet L C M van Riel, Yonghong Li, Paul I W de Bakker, Peter K Gregersen, Jane Worthington, Katherine A Siminovitch, Lars Klareskog, Tom W J Huizinga, Cisca Wijmenga, Robert M Plenge
Published 2011-02-01

Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies.

by Ilja M Nolte, Chris Wallace, Stephen J Newhouse, Daryl Waggott, Jingyuan Fu, Nicole Soranzo, Rhian Gwilliam, Panos Deloukas, Irina Savelieva, Dongling Zheng, Chrysoula Dalageorgou, Martin Farrall, Nilesh J Samani, John Connell, Morris Brown, Anna Dominiczak, Mark Lathrop, Eleftheria Zeggini, Louise V Wain, Wellcome Trust Case Control Consortium, DCCT/EDIC Research Group, Christopher Newton-Cheh, Mark Eijgelsheim, Kenneth Rice, Paul I W de Bakker, QTGEN consortium, Arne Pfeufer, Serena Sanna, Dan E Arking, QTSCD consortium, Folkert W Asselbergs, Tim D Spector, Nicholas D Carter, Steve Jeffery, Martin Tobin, Mark Caulfield, Harold Snieder, Andrew D Paterson, Patricia B Munroe, Yalda Jamshidi
Published 2009-07-01

GWAS identifies novel susceptibility loci on 6p21.32 and 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers.

by Shengping Li, Ji Qian, Yuan Yang, Wanting Zhao, Juncheng Dai, Jin-Xin Bei, Jia Nee Foo, Paul J McLaren, Zhiqiang Li, Jingmin Yang, Feng Shen, Li Liu, Jiamei Yang, Shuhong Li, Shandong Pan, Yi Wang, Wenjin Li, Xiangjun Zhai, Boping Zhou, Lehua Shi, Xinchun Chen, Minjie Chu, Yiqun Yan, Jun Wang, Shuqun Cheng, Jiawei Shen, Weihua Jia, Jibin Liu, Jiahe Yang, Zujia Wen, Aijun Li, Ying Zhang, Guoliang Zhang, Xianrong Luo, Hongbo Qin, Minshan Chen, Hua Wang, Li Jin, Dongxin Lin, Hongbing Shen, Lin He, Paul I W de Bakker, Hongyang Wang, Yi-Xin Zeng, Mengchao Wu, Zhibin Hu, Yongyong Shi, Jianjun Liu, Weiping Zhou
Published 2012-01-01