Predicting signatures of "synthetic associations" and "natural associations" from empirical patterns of human genetic variation.

by Diana Chang, Alon Keinan
Published 2012-01-01

Principal component analysis characterizes shared pathogenetics from genome-wide association studies.

by Diana Chang, Alon Keinan
Published 2014-09-01

Human population differentiation is strongly correlated with local recombination rate.

by Alon Keinan, David Reich
Published 2010-03-01

Gene-based testing of interactions in association studies of quantitative traits.

by Li Ma, Andrew G Clark, Alon Keinan
Published 2013-01-01

Combining Sparse Group Lasso and Linear Mixed Model Improves Power to Detect Genetic Variants Underlying Quantitative Traits

by Yingjie Guo, Yingjie Guo, Chenxi Wu, Maozu Guo, Maozu Guo, Quan Zou, Xiaoyan Liu, Alon Keinan, Alon Keinan
Published 2019-04-01

Analysis of multiple association studies provides evidence of an expression QTL hub in gene-gene interaction network affecting HDL cholesterol levels.

by Li Ma, Christie Ballantyne, Ariel Brautbar, Alon Keinan
Published 2014-01-01

Quantitative analysis of genetic and neuronal multi-perturbation experiments.

by Alon Kaufman, Alon Keinan, Isaac Meilijson, Martin Kupiec, Eytan Ruppin
Published 2005-11-01

Gene-Based Nonparametric Testing of Interactions Using Distance Correlation Coefficient in Case-Control Association Studies

by Yingjie Guo, Chenxi Wu, Maozu Guo, Xiaoyan Liu, Alon Keinan
Published 2018-12-01

Interaction between SNPs in the RXRA and near ANGPTL3 gene region inhibits apoB reduction after statin-fenofibric acid therapy in individuals with mixed dyslipidemia

by Li Ma, Christie M. Ballantyne, John W. Belmont, Alon Keinan, Ariel Brautbar
Published 2012-11-01

Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations.

by Li Ma, Ariel Brautbar, Eric Boerwinkle, Charles F Sing, Andrew G Clark, Alon Keinan
Published 2012-01-01

The history of African gene flow into Southern Europeans, Levantines, and Jews.

by Priya Moorjani, Nick Patterson, Joel N Hirschhorn, Alon Keinan, Li Hao, Gil Atzmon, Edward Burns, Harry Ostrer, Alkes L Price, David Reich
Published 2011-04-01

Accounting for eXentricities: analysis of the X chromosome in GWAS reveals X-linked genes implicated in autoimmune diseases.

by Diana Chang, Feng Gao, Andrea Slavney, Li Ma, Yedael Y Waldman, Aaron J Sams, Paul Billing-Ross, Aviv Madar, Richard Spritz, Alon Keinan
Published 2014-01-01

The Genetics of Bene Israel from India Reveals Both Substantial Jewish and Indian Ancestry.

by Yedael Y Waldman, Arjun Biddanda, Natalie R Davidson, Paul Billing-Ross, Maya Dubrovsky, Christopher L Campbell, Carole Oddoux, Eitan Friedman, Gil Atzmon, Eran Halperin, Harry Ostrer, Alon Keinan
Published 2016-01-01

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

by Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Published 2019-09-01

Population genomic analysis of 962 whole genome sequences of humans reveals natural selection in non-coding regions.

by Fuli Yu, Jian Lu, Xiaoming Liu, Elodie Gazave, Diana Chang, Srilakshmi Raj, Haley Hunter-Zinck, Ran Blekhman, Leonardo Arbiza, Cris Van Hout, Alanna Morrison, Andrew D Johnson, Joshua Bis, L Adrienne Cupples, Bruce M Psaty, Donna Muzny, Jin Yu, Richard A Gibbs, Alon Keinan, Andrew G Clark, Eric Boerwinkle
Published 2015-01-01