The challenge of producing skin test antigens with minimal resources suitable for human application against a neglected tropical disease; leprosy.

by Becky L Rivoire, Stephen TerLouw, Nathan A Groathouse, Patrick J Brennan
Published 2014-01-01

Infection by Mycobacterium leprae of household contacts of lepromatous leprosy patients from a post-elimination leprosy region of Colombia

by Nora M Cardona-Castro, Sandra Restrepo-Jaramillo, Myriam Gil de la Ossa, Patrick J Brennan
Published 2005-11-01

Serum metabolomics reveals higher levels of polyunsaturated fatty acids in lepromatous leprosy: potential markers for susceptibility and pathogenesis.

by Reem Al-Mubarak, Jason Vander Heiden, Corey D Broeckling, Marivic Balagon, Patrick J Brennan, Varalakshmi D Vissa
Published 2011-09-01

A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling

by Carlos A. Donado, Anh B. Cao, Daimon P. Simmons, Ben A. Croker, Patrick J. Brennan, Michael B. Brenner
Published 2020-04-01

Identification of a novel class of ω,E,E-farnesyl diphosphate synthase from Mycobacterium tuberculosis

by Rakesh K. Dhiman, Mark C. Schulbach, Sebabrata Mahapatra, Alain R. Baulard, Varalakshmi Vissa, Patrick J. Brennan, Dean C. Crick
Published 2004-06-01

Stable extracellular RNA fragments of Mycobacterium tuberculosis induce early apoptosis in human monocytes via a caspase-8 dependent mechanism.

by Andrés Obregón-Henao, María A Duque-Correa, Mauricio Rojas, Luis F García, Patrick J Brennan, Blanca L Ortiz, John T Belisle
Published 2012-01-01

Initiation of methylglucose lipopolysaccharide biosynthesis in mycobacteria.

by Devinder Kaur, Ha Pham, Gérald Larrouy-Maumus, Michel Rivière, Varalakshmi Vissa, Marcelo E Guerin, Germain Puzo, Patrick J Brennan, Mary Jackson
Published 2009-01-01

Long-term survival and virulence of Mycobacterium leprae in amoebal cysts.

by William H Wheat, Amy L Casali, Vincent Thomas, John S Spencer, Ramanuj Lahiri, Diana L Williams, Gerald E McDonnell, Mercedes Gonzalez-Juarrero, Patrick J Brennan, Mary Jackson
Published 2014-12-01

Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions

by Maria Gutierrez-Arcelus, Nikola Teslovich, Alex R. Mola, Rafael B. Polidoro, Aparna Nathan, Hyun Kim, Susan Hannes, Kamil Slowikowski, Gerald F. M. Watts, Ilya Korsunsky, Michael B. Brenner, Soumya Raychaudhuri, Patrick J. Brennan
Published 2019-02-01

Effective Reduction in Opioid Prescriptions for Ambulatory Lesion Excisions in Pediatric Patients

by Rachel A. McKenna, CRNP, Alfred Lee, MD, Chen Yan, MD, Giap H. Vu, BA, Ellen C. Jantzen, MD, Patrick J. Brennan, RN, Adam Watson, PMP, LSSGB, Caroline Burlingame, MPH, Ines C. Lin, MD, MSEd
Published 2021-03-01

Identification of serological biomarkers of infection, disease progression and treatment efficacy for leprosy

by John S Spencer, Malcolm S Duthie, Annemieke Geluk, Marivic F Balagon, Hee Jin Kim, William H Wheat, Delphi Chatterjee, Mary Jackson, Wei Li, Jade N Kurihara, Armi Maghanoy, Irene Mallari, Paul Saunderson, Patrick J Brennan, Hazel M Dockrell
Published 2012-12-01

Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells.

by Xinli Hu, Hyun Kim, Towfique Raj, Patrick J Brennan, Gosia Trynka, Nikola Teslovich, Kamil Slowikowski, Wei-Min Chen, Suna Onengut, Clare Baecher-Allan, Philip L De Jager, Stephen S Rich, Barbara E Stranger, Michael B Brenner, Soumya Raychaudhuri
Published 2014-06-01

Samovar: Single-Sample Mosaic Single-Nucleotide Variant Calling with Linked Reads

by Charlotte A. Darby, James R. Fitch, Patrick J. Brennan, Benjamin J. Kelly, Natalie Bir, Vincent Magrini, Jeffrey Leonard, Catherine E. Cottrell, Julie M. Gastier-Foster, Richard K. Wilson, Elaine R. Mardis, Peter White, Ben Langmead, Michael C. Schatz
Published 2019-08-01

Genotyping of Mycobacterium leprae for better understanding of leprosy transmission in Fortaleza, Northeastern Brazil.

by Amanda N B Fontes, Luana N G C Lima, Rosa M S Mota, Rosa L F Almeida, Maria A Pontes, Heitor de S Gonçalves, Cristiane C Frota, Varalakshmi D Vissa, Patrick J Brennan, Ricardo J P S Guimaraes, Carl Kendall, Ligia R F S Kerr, Philip N Suffys
Published 2017-12-01

Safety and efficacy assessment of two new leprosy skin test antigens: randomized double blind clinical study.

by Becky L Rivoire, Nathan A Groathouse, Stephen TerLouw, Kapil Dev Neupane, Chaman Ranjit, Bishwa Raj Sapkota, Saraswoti Khadge, Chhatra B Kunwar, Murdo Macdonald, Rachel Hawksworth, Min B Thapa, Deanna A Hagge, Melinda Tibbals, Carol Smith, Tina Dube, Dewei She, Mark Wolff, Eric Zhou, Mamodikoe Makhene, Robin Mason, Christine Sizemore, Patrick J Brennan
Published 2014-01-01

Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis

by Thabatta L. S. A. Rosa, Maria Angela M. Marques, Zachary DeBoard, Kelly Hutchins, Carlos Adriano A. Silva, Christine R. Montague, Tianao Yuan, Julio J. Amaral, Georgia C. Atella, Patrícia S. Rosa, Katherine A. Mattos, Brian C. VanderVen, Ramanuj Lahiri, Nicole S. Sampson, Patrick J. Brennan, John T. Belisle, Maria Cristina V. Pessolani, Marcia Berrêdo-Pinho
Published 2021-07-01

Corrigendum: Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis

by Thabatta L. S. A. Rosa, Maria Angela M. Marques, Zachary DeBoard, Kelly Hutchins, Carlos Adriano A. Silva, Christine R. Montague, Tianao Yuan, Julio J. Amaral, Georgia C. Atella, Patrícia S. Rosa, Katherine A. Mattos, Brian C. VanderVen, Ramanuj Lahiri, Nicole S. Sampson, Patrick J. Brennan, John T. Belisle, Maria Cristina V. Pessolani, Marcia Berrêdo-Pinho
Published 2021-09-01

Pathogen-specific epitopes as epidemiological tools for defining the magnitude of Mycobacterium leprae transmission in areas endemic for leprosy.

by Marcia V S B Martins, Marjorie M da S Guimarães, John S Spencer, Mariana A V B Hacker, Luciana S Costa, Fernanda M Carvalho, Annemieke Geluk, Jolien J van der Ploeg-van Schip, Maria A A Pontes, Heitor S Gonçalves, Janvier P de Morais, Tereza J P G Bandeira, Maria C V Pessolani, Patrick J Brennan, Geraldo M B Pereira
Published 2012-01-01

Genotyping of Mycobacterium leprae present on Ziehl-Neelsen-stained microscopic slides and in skin biopsy samples from leprosy patients in different geographic regions of Brazil

by Amanda Nogueira Brum Fontes, Harrison Magdinier Gomes, Marcelo Ivens de Araujo, Edson Cláudio Araripe de Albuquerque, Ida Maria Foschiani Dias Baptista, Maria Manuela da Fonseca Moura, Denise Silva Rezende, Maria Cristina Vidal Pessolani, Flávio Alves Lara, Maria Araci de Andrade Pontes, Heitor de Sá Gonçalves, Norma Lucena-Silva, Euzenir Nunes Sarno, Varalakshmi D Vissa, Patrick J Brennan, Philip Noel Suffys
Published 2012-12-01

IFNgamma response to Mycobacterium tuberculosis, risk of infection and disease in household contacts of tuberculosis patients in Colombia.

by Helena del Corral, Sara C París, Nancy D Marín, Diana M Marín, Lucelly López, Hanna M Henao, Teresita Martínez, Liliana Villa, Luis F Barrera, Blanca L Ortiz, María E Ramírez, Carlos J Montes, María C Oquendo, Lisandra M Arango, Felipe Riaño, Carlos Aguirre, Alberto Bustamante, John T Belisle, Karen Dobos, Gloria I Mejía, Margarita R Giraldo, Patrick J Brennan, Jaime Robledo, María P Arbeláez, Carlos A Rojas, Luis F García
Published 2009-12-01