Translating the human microbiome: a path to improving health

by Ramnik J. Xavier
Published 2021-05-01

Dissecting the human microbiome with single-cell genomics

by Andrew C. Tolonen, Ramnik J. Xavier
Published 2017-06-01

Comprehensive analysis of chromosomal mobile genetic elements in the gut microbiome reveals phylum-level niche-adaptive gene pools.

by Xiaofang Jiang, Andrew Brantley Hall, Ramnik J Xavier, Eric J Alm
Published 2019-01-01

SAC1 regulates autophagosomal phosphatidylinositol-4-phosphate for xenophagy-directed bacterial clearance

by Kai Liu, Lingjia Kong, Daniel B. Graham, Kimberly L. Carey, Ramnik J. Xavier
Published 2021-07-01

Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant.

by Petric Kuballa, Alan Huett, John D Rioux, Mark J Daly, Ramnik J Xavier
Published 2008-01-01

Bacterial and host determinants of MAL activation upon EPEC infection: the roles of Tir, ABRA, and FLRT3.

by Robert J W Heath, John M Leong, Balázs Visegrády, Laura M Machesky, Ramnik J Xavier
Published 2011-04-01

HCV causes chronic endoplasmic reticulum stress leading to adaptation and interference with the unfolded protein response.

by Emmanuelle Merquiol, Dotan Uzi, Tobias Mueller, Daniel Goldenberg, Yaakov Nahmias, Ramnik J Xavier, Boaz Tirosh, Oren Shibolet
Published 2011-01-01

The T300A Crohn’s disease risk polymorphism impairs function of the WD40 domain of ATG16L1

by Emilio Boada-Romero, Inmaculada Serramito-Gómez, María P. Sacristán, David L. Boone, Ramnik J. Xavier, Felipe X. Pimentel-Muiños
Published 2016-06-01

Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice.

by Ianina C Ferder, Leslie Fung, Yasuyo Ohguchi, Xiaoyu Zhang, Kara G Lassen, Diane Capen, Dennis Brown, Ramnik J Xavier, Ning Wang
Published 2019-05-01

Control and manipulation of pathogens with an optical trap for live cell imaging of intercellular interactions.

by Jenny M Tam, Carlos E Castro, Robert J W Heath, Michael L Cardenas, Ramnik J Xavier, Matthew J Lang, Jatin M Vyas
Published 2010-12-01

Host genetic variation and its microbiome interactions within the Human Microbiome Project

by Raivo Kolde, Eric A. Franzosa, Gholamali Rahnavard, Andrew Brantley Hall, Hera Vlamakis, Christine Stevens, Mark J. Daly, Ramnik J. Xavier, Curtis Huttenhower
Published 2018-01-01

Fruit and vegetable consumption is associated with lower prevalence of asymptomatic diverticulosis: a cross-sectional colonoscopy-based study

by Benjamin Maxner, Jessica McGoldrick, Danielle Bellavance, Po-Hong Liu, Ramnik J. Xavier, Joseph C. Yarze, Rocco Ricciardi, Kyle Staller, Daniel C. Chung, Hamed Khalili
Published 2020-07-01

An image-based genetic assay identifies genes in T1D susceptibility loci controlling cellular antiviral immunity in mouse.

by Juan Liao, Humberto B Jijon, Ira R Kim, Gautam Goel, Aivi Doan, Harry Sokol, Hermann Bauer, Bernhard G Herrmann, Kara G Lassen, Ramnik J Xavier
Published 2014-01-01

Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.

by Elizabeth J Rossin, Kasper Lage, Soumya Raychaudhuri, Ramnik J Xavier, Diana Tatar, Yair Benita, International Inflammatory Bowel Disease Genetics Constortium, Chris Cotsapas, Mark J Daly
Published 2011-01-01

Predictive metabolomic profiling of microbial communities using amplicon or metagenomic sequences

by Himel Mallick, Eric A. Franzosa, Lauren J. Mclver, Soumya Banerjee, Alexandra Sirota-Madi, Aleksandar D. Kostic, Clary B. Clish, Hera Vlamakis, Ramnik J. Xavier, Curtis Huttenhower
Published 2019-07-01

A Novel Role for Kruppel-like Factor 14 (KLF14) in T-Regulatory Cell DifferentiationSummary

by Olga F. Sarmento, Phyllis A. Svingen, Yuning Xiong, Ramnik J. Xavier, Dermot McGovern, Thomas C. Smyrk, Konstantinos A. Papadakis, Raul A. Urrutia, William A. Faubion
Published 2015-03-01

Recurrent chromosomal copy number alterations in sporadic chordomas.

by Long Phi Le, G Petur Nielsen, Andrew Eric Rosenberg, Dafydd Thomas, Julie M Batten, Vikram Deshpande, Joseph Schwab, Zhenfeng Duan, Ramnik J Xavier, Francis J Hornicek, A John Iafrate
Published 2011-01-01

p40phox-Deficient Mice Exhibit Impaired Bacterial Clearance and Enhanced Pro-inflammatory Responses during Salmonella enterica serovar Typhimurium Infection

by Yali Li, Yali Li, Yali Li, Meili Lv, Meili Lv, Chienwen Su, Shaorong Long, Wei Zhang, Wei Zhang, Kara L. Conway, Weifen Li, Ramnik J. Xavier, Hai Ning Shi
Published 2017-10-01

Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9

by Jonathan M. Goodwin, William E. Dowdle, Rowena DeJesus, Zuncai Wang, Philip Bergman, Marek Kobylarz, Alicia Lindeman, Ramnik J. Xavier, Gregory McAllister, Beat Nyfeler, Gregory Hoffman, Leon O. Murphy
Published 2017-09-01

SLC39A8 missense variant is associated with Crohn's disease but does not have a major impact on gut microbiome composition in healthy subjects.

by Valerie Collij, Floris Imhann, Arnau Vich Vila, Jingyuan Fu, Gerard Dijkstra, Eleonora A M Festen, Michiel D Voskuil, Mark J Daly, Ramnik J Xavier, Cisca Wijmenga, Alexandra Zhernakova, Rinse K Weersma
Published 2019-01-01