GAD1 mRNA expression and DNA methylation in prefrontal cortex of subjects with schizophrenia.

by Hsien-Sung Huang, Schahram Akbarian
Published 2007-08-01

Epigenetic and post-transcriptional dysregulation of gene expression in schizophrenia and related disease

by David P. Gavin, Schahram Akbarian
Published 2012-05-01

Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood.

by Hennady P Shulha, Iris Cheung, Yin Guo, Schahram Akbarian, Zhiping Weng
Published 2013-04-01

Cognition and mood-related behaviors in L3mbtl1 null mutant mice.

by Erica Y Shen, Yan Jiang, Wenjie Mao, Kensuke Futai, Hanno Hock, Schahram Akbarian
Published 2015-01-01

Modeling Neuropsychiatric and Neurodegenerative Diseases With Induced Pluripotent Stem Cells

by Elizabeth A. LaMarca, Elizabeth A. LaMarca, Elizabeth A. LaMarca, Elizabeth A. LaMarca, Samuel K. Powell, Samuel K. Powell, Samuel K. Powell, Samuel K. Powell, Schahram Akbarian, Schahram Akbarian, Schahram Akbarian, Kristen J. Brennand, Kristen J. Brennand, Kristen J. Brennand, Kristen J. Brennand
Published 2018-04-01

The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism.

by Chunxing Yang, Weijia Tan, Catheryne Whittle, Linghua Qiu, Lucheng Cao, Schahram Akbarian, Zuoshang Xu
Published 2010-12-01

An Adolescent Sensitive Period for Social Dominance Hierarchy Plasticity Is Regulated by Cortical Plasticity Modulators in Mice

by Lucy K. Bicks, Lucy K. Bicks, Lucy K. Bicks, Lucy K. Bicks, Lucy K. Bicks, Michelle Peng, Michelle Peng, Michelle Peng, Michelle Peng, Michelle Peng, Alana Taub, Alana Taub, Alana Taub, Alana Taub, Alana Taub, Schahram Akbarian, Schahram Akbarian, Schahram Akbarian, Hirofumi Morishita, Hirofumi Morishita, Hirofumi Morishita, Hirofumi Morishita, Hirofumi Morishita
Published 2021-05-01

The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease.

by Xianjun Dong, Junko Tsuji, Adam Labadorf, Panos Roussos, Jiang-Fan Chen, Richard H Myers, Schahram Akbarian, Zhiping Weng
Published 2015-01-01

Expression Pattern of the Rett Syndrome Gene MeCP2 in Primate Prefrontal Cortex

by Schahram Akbarian, Richard Z Chen, Joost Gribnau, Theodore P Rasmussen, Hiu-fai Fong, Rudolf Jaenisch, Edward G Jones
Published 2001-10-01

Activity-Induced Regulation of Synaptic Strength through the Chromatin Reader L3mbtl1

by Wenjie Mao, Anna C. Salzberg, Motokazu Uchigashima, Yuto Hasegawa, Hanno Hock, Masahiko Watanabe, Schahram Akbarian, Yuka Imamura Kawasawa, Kensuke Futai
Published 2018-06-01

Neurotrophin-3 Promotes Cell Death Induced in Cerebral Ischemia, Oxygen-Glucose Deprivation, and Oxidative Stress: Possible Involvement of Oxygen Free Radicals

by Brian Bates, Lorenz Hirt, Sunu S. Thomas, Schahram Akbarian, Dean Le, Sepideh Amin-Hanjani, Michael Whalen, Rudolf Jaenisch, Michael A. Moskowitz
Published 2002-02-01

DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons.

by Kimberly D Siegmund, Caroline M Connor, Mihaela Campan, Tiffany I Long, Daniel J Weisenberger, Detlev Biniszkiewicz, Rudolf Jaenisch, Peter W Laird, Schahram Akbarian
Published 2007-01-01

Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes

by Seok-Man Ho, Brigham J. Hartley, Erin Flaherty, Prashanth Rajarajan, Rawan Abdelaal, Ifeanyi Obiorah, Natalie Barretto, Hamza Muhammad, Hemali P. Phatnani, Schahram Akbarian, Kristen J. Brennand
Published 2017-08-01

Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex

by Amanda C. Mitchell, Behnam Javidfar, Lucy K. Bicks, Rachael Neve, Krassimira Garbett, Sharon S. Lander, Karoly Mirnics, Hirofumi Morishita, Marcelo A. Wood, Yan Jiang, Inna Gaisler-Salomon, Schahram Akbarian
Published 2016-09-01

Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice

by Ryan M. Walsh, Erica Y. Shen, Rosemary C. Bagot, Anthony Anselmo, Yan Jiang, Behnam Javidfar, Gregory J. Wojtkiewicz, Jennifer Cloutier, John W. Chen, Ruslan Sadreyev, Eric J. Nestler, Schahram Akbarian, Konrad Hochedlinger
Published 2017-05-01

MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis.

by Andrew G Hoss, Vinay K Kartha, Xianjun Dong, Jeanne C Latourelle, Alexandra Dumitriu, Tiffany C Hadzi, Marcy E Macdonald, James F Gusella, Schahram Akbarian, Jiang-Fan Chen, Zhiping Weng, Richard H Myers
Published 2014-02-01

Correction: RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression.

by Adam Labadorf, Andrew G Hoss, Valentina Lagomarsino, Jeanne C Latourelle, Tiffany C Hadzi, Joli Bregu, Marcy E MacDonald, James F Gusella, Jiang-Fan Chen, Schahram Akbarian, Zhiping Weng, Richard H Myers
Published 2016-01-01

RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression.

by Adam Labadorf, Andrew G Hoss, Valentina Lagomarsino, Jeanne C Latourelle, Tiffany C Hadzi, Joli Bregu, Marcy E MacDonald, James F Gusella, Jiang-Fan Chen, Schahram Akbarian, Zhiping Weng, Richard H Myers
Published 2015-01-01

Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders

by Benxia Hu, Hyejung Won, Won Mah, Royce B. Park, Bibi Kassim, Keeley Spiess, Alexey Kozlenkov, Cheynna A. Crowley, Sirisha Pochareddy, The PsychENCODE Consortium, Yun Li, Stella Dracheva, Nenad Sestan, Schahram Akbarian, Daniel H. Geschwind
Published 2021-06-01

Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism.

by Xiling Liu, Dingding Han, Mehmet Somel, Xi Jiang, Haiyang Hu, Patricia Guijarro, Ning Zhang, Amanda Mitchell, Tobias Halene, John J Ely, Chet C Sherwood, Patrick R Hof, Zilong Qiu, Svante Pääbo, Schahram Akbarian, Philipp Khaitovich
Published 2016-09-01