Dynamic metabolic flux analysis using B-splines to study the effects of temperature shift on CHO cell metabolism

by Verónica S. Martínez, Maria Buchsteiner, Peter Gray, Lars K. Nielsen, Lake-Ee Quek
Published 2015-12-01

A multi-omics analysis of recombinant protein production in Hek293 cells.

by Stefanie Dietmair, Mark P Hodson, Lake-Ee Quek, Nicholas E Timmins, Peter Gray, Lars K Nielsen
Published 2012-01-01

Snail-Overexpression Induces Epithelial-mesenchymal Transition and Metabolic Reprogramming in Human Pancreatic Ductal Adenocarcinoma and Non-tumorigenic Ductal Cells

by Menghan Liu, Sarah E. Hancock, Ghazal Sultani, Brendan P. Wilkins, Eileen Ding, Brenna Osborne, Lake-Ee Quek, Nigel Turner
Published 2019-06-01

Metabolic profiling and flux analysis of MEL-2 human embryonic stem cells during exponential growth at physiological and atmospheric oxygen concentrations.

by Jennifer Turner, Lake-Ee Quek, Drew Titmarsh, Jens O Krömer, Li-Pin Kao, Lars Nielsen, Ernst Wolvetang, Justin Cooper-White
Published 2014-01-01

Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways

by Michelle van Geldermalsen, Lake-Ee Quek, Nigel Turner, Natasha Freidman, Angel Pang, Yi Fang Guan, James R. Krycer, Renae Ryan, Qian Wang, Jeff Holst
Published 2018-06-01

Kinetic Trans-omic Analysis Reveals Key Regulatory Mechanisms for Insulin-Regulated Glucose Metabolism in Adipocytes

by Satoshi Ohno, Lake-Ee Quek, James R. Krycer, Katsuyuki Yugi, Akiyoshi Hirayama, Satsuki Ikeda, Futaba Shoji, Kumi Suzuki, Tomoyoshi Soga, David E. James, Shinya Kuroda
Published 2020-09-01

Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin

by Lake-Ee Quek, James R. Krycer, Satoshi Ohno, Katsuyuki Yugi, Daniel J. Fazakerley, Richard Scalzo, Sarah D. Elkington, Ziwei Dai, Akiyoshi Hirayama, Satsuki Ikeda, Futaba Shoji, Kumi Suzuki, Jason W. Locasale, Tomoyoshi Soga, David E. James, Shinya Kuroda
Published 2020-12-01

Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin

by Lake-Ee Quek, James R. Krycer, Satoshi Ohno, Katsuyuki Yugi, Daniel J. Fazakerley, Richard Scalzo, Sarah D. Elkington, Ziwei Dai, Akiyoshi Hirayama, Satsuki Ikeda, Futaba Shoji, Kumi Suzuki, Jason W. Locasale, Tomoyoshi Soga, David E. James, Shinya Kuroda
Published 2020-02-01

A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth

by Joanna L Gillis, Josephine A Hinneh, Natalie K Ryan, Swati Irani, Max Moldovan, Lake-Ee Quek, Raj K Shrestha, Adrienne R Hanson, Jianling Xie, Andrew J Hoy, Jeff Holst, Margaret M Centenera, Ian G Mills, David J Lynn, Luke A Selth, Lisa M Butler
Published 2021-08-01

Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism

by James R. Krycer, Katsuyuki Yugi, Akiyoshi Hirayama, Daniel J. Fazakerley, Lake-Ee Quek, Richard Scalzo, Satoshi Ohno, Mark P. Hodson, Satsuki Ikeda, Futaba Shoji, Kumi Suzuki, Westa Domanova, Benjamin L. Parker, Marin E. Nelson, Sean J. Humphrey, Nigel Turner, Kyle L. Hoehn, Gregory J. Cooney, Tomoyoshi Soga, Shinya Kuroda, David E. James
Published 2017-12-01

Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress

by Frances L. Byrne, Ellen M. Olzomer, Gabriella R. Marriott, Lake-Ee Quek, Alice Katen, Jacky Su, Marin E. Nelson, Gene Hart-Smith, Mark Larance, Veronica F. Sebesfi, Jeff Cuff, Gabriella E. Martyn, Elizabeth Childress, Stephanie J. Alexopoulos, Ivan K. Poon, Maree C. Faux, Antony W. Burgess, Glen Reid, Joshua A. McCarroll, Webster L. Santos, Kate GR. Quinlan, Nigel Turner, Daniel J. Fazakerley, Naresh Kumar, Kyle L. Hoehn
Published 2020-01-01