Quality Assessment of Untargeted Analytical Data in a Large-Scale Metabolomic Study

by Rintaro Saito, Masahiro Sugimoto, Akiyoshi Hirayama, Tomoyoshi Soga, Masaru Tomita, Toru Takebayashi
Published 2021-04-01

Dynamic simulation and metabolome analysis of long-term erythrocyte storage in adenine-guanosine solution.

by Taiko Nishino, Ayako Yachie-Kinoshita, Akiyoshi Hirayama, Tomoyoshi Soga, Makoto Suematsu, Masaru Tomita
Published 2013-01-01

Metabolomic Analysis of Small Extracellular Vesicles Derived from Pancreatic Cancer Cells Cultured under Normoxia and Hypoxia

by Ryosuke Hayasaka, Sho Tabata, Masako Hasebe, Satsuki Ikeda, Sumiko Ohnuma, Masaru Mori, Tomoyoshi Soga, Masaru Tomita, Akiyoshi Hirayama
Published 2021-04-01

Xanthurenic Acid Is the Main Pigment of <i>Trichonephila clavata</i> Gold Dragline Silk

by Masayuki Fujiwara, Nobuaki Kono, Akiyoshi Hirayama, Ali D. Malay, Hiroyuki Nakamura, Rintaro Ohtoshi, Keiji Numata, Masaru Tomita, Kazuharu Arakawa
Published 2021-04-01

Adenosine leakage from perforin-burst extracellular vesicles inhibits perforin secretion by cytotoxic T-lymphocytes.

by Hiroko Tadokoro, Akiyoshi Hirayama, Ryuhei Kudo, Masako Hasebe, Yusuke Yoshioka, Juntaro Matsuzaki, Yusuke Yamamoto, Masahiro Sugimoto, Tomoyoshi Soga, Takahiro Ochiya
Published 2020-01-01

A Metabolomic Profile Predictive of New Osteoporosis or Sarcopenia Development

by Kana Miyamoto, Akiyoshi Hirayama, Yuiko Sato, Satsuki Ikeda, Midori Maruyama, Tomoyoshi Soga, Masaru Tomita, Masaya Nakamura, Morio Matsumoto, Noriko Yoshimura, Takeshi Miyamoto
Published 2021-04-01

Comprehensive Dipeptide Analysis Revealed Cancer-Specific Profile in the Liver of Patients with Hepatocellular Carcinoma and Hepatitis

by Hitoshi Ozawa, Akiyoshi Hirayama, Futaba Shoji, Midori Maruyama, Kumi Suzuki, Hisami Yamanaka-Okumura, Hiroshi Tatano, Yuji Morine, Tomoyoshi Soga, Mitsuo Shimada, Masaru Tomita
Published 2020-11-01

A Metabologenomic Approach Reveals Changes in the Intestinal Environment of Mice Fed on American Diet

by Chiharu Ishii, Yumiko Nakanishi, Shinnosuke Murakami, Ryoko Nozu, Masami Ueno, Kyoji Hioki, Wanping Aw, Akiyoshi Hirayama, Tomoyoshi Soga, Mamoru Ito, Masaru Tomita, Shinji Fukuda
Published 2018-12-01

Kinetic Trans-omic Analysis Reveals Key Regulatory Mechanisms for Insulin-Regulated Glucose Metabolism in Adipocytes

by Satoshi Ohno, Lake-Ee Quek, James R. Krycer, Katsuyuki Yugi, Akiyoshi Hirayama, Satsuki Ikeda, Futaba Shoji, Kumi Suzuki, Tomoyoshi Soga, David E. James, Shinya Kuroda
Published 2020-09-01

Seaweed Dietary Fiber Sodium Alginate Suppresses the Migration of Colonic Inflammatory Monocytes and Diet-Induced Metabolic Syndrome via the Gut Microbiota

by Ryuta Ejima, Masahiro Akiyama, Hiroki Sato, Sawako Tomioka, Kyosuke Yakabe, Tatsuki Kimizuka, Natsumi Seki, Yumiko Fujimura, Akiyoshi Hirayama, Shinji Fukuda, Koji Hase, Yun-Gi Kim
Published 2021-08-01

Asperuloside Improves Obesity and Type 2 Diabetes through Modulation of Gut Microbiota and Metabolic Signaling

by Anna Nakamura, Yoko Yokoyama, Kazuki Tanaka, Giorgia Benegiamo, Akiyoshi Hirayama, Qi Zhu, Naho Kitamura, Taichi Sugizaki, Kohkichi Morimoto, Hiroshi Itoh, Shinji Fukuda, Johan Auwerx, Kazuo Tsubota, Mitsuhiro Watanabe
Published 2020-09-01

A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity

by Mitsuhiro Endoh, Masaya Baba, Tamie Endoh, Akiyoshi Hirayama, Ayako Nakamura-Ishizu, Terumasa Umemoto, Michihiro Hashimoto, Kunio Nagashima, Tomoyoshi Soga, Martin Lang, Laura S. Schmidt, W. Marston Linehan, Toshio Suda
Published 2020-02-01

A Metabolomic-Based Evaluation of the Role of Commensal Microbiota throughout the Gastrointestinal Tract in Mice

by Yuri Yamamoto, Yumiko Nakanishi, Shinnosuke Murakami, Wanping Aw, Tomoya Tsukimi, Ryoko Nozu, Masami Ueno, Kyoji Hioki, Kenji Nakahigashi, Akiyoshi Hirayama, Masahiro Sugimoto, Tomoyoshi Soga, Mamoru Ito, Masaru Tomita, Shinji Fukuda
Published 2018-09-01

Comparative analysis of cerebrospinal fluid metabolites in Alzheimer’s disease and idiopathic normal pressure hydrocephalus in a Japanese cohort

by Yuki Nagata, Akiyoshi Hirayama, Satsuki Ikeda, Aoi Shirahata, Futaba Shoji, Midori Maruyama, Mitsunori Kayano, Masahiko Bundo, Kotaro Hattori, Sumiko Yoshida, Yu-ichi Goto, Katsuya Urakami, Tomoyoshi Soga, Kouichi Ozaki, Shumpei Niida
Published 2018-01-01

Correction: Charged metabolite biomarkers of food intake assessed via plasma metabolomics in a population-based observational study in Japan.

by Eriko Shibutami, Ryota Ishii, Sei Harada, Ayako Kurihara, Kazuyo Kuwabara, Suzuka Kato, Miho Iida, Miki Akiyama, Daisuke Sugiyama, Akiyoshi Hirayama, Asako Sato, Kaori Amano, Masahiro Sugimoto, Tomoyoshi Soga, Masaru Tomita, Toru Takebayashi
Published 2021-01-01

Charged metabolite biomarkers of food intake assessed via plasma metabolomics in a population-based observational study in Japan.

by Eriko Shibutami, Ryota Ishii, Sei Harada, Ayako Kurihara, Kazuyo Kuwabara, Suzuka Kato, Miho Iida, Miki Akiyama, Daisuke Sugiyama, Akiyoshi Hirayama, Asako Sato, Kaori Amano, Masahiro Sugimoto, Tomoyoshi Soga, Masaru Tomita, Toru Takebayashi
Published 2021-01-01

Metabolomics-based profiles predictive of low bone mass in menopausal women

by Takeshi Miyamoto, Akiyoshi Hirayama, Yuiko Sato, Tami Koboyashi, Eri Katsuyama, Hiroya Kanagawa, Atsuhiro Fujie, Mayu Morita, Ryuichi Watanabe, Toshimi Tando, Kana Miyamoto, Takashi Tsuji, Atsushi Funayama, Tomoyoshi Soga, Masaru Tomita, Masaya Nakamura, Morio Matsumoto
Published 2018-12-01

TGF-β-dependent reprogramming of amino acid metabolism induces epithelial–mesenchymal transition in non-small cell lung cancers

by Fumie Nakasuka, Sho Tabata, Takeharu Sakamoto, Akiyoshi Hirayama, Hiromichi Ebi, Tadaaki Yamada, Ko Umetsu, Maki Ohishi, Ayano Ueno, Hisatsugu Goto, Masahiro Sugimoto, Yasuhiko Nishioka, Yasuhiro Yamada, Masaru Tomita, Atsuo T. Sasaki, Seiji Yano, Tomoyoshi Soga
Published 2021-06-01

Metabolic Profiling of Total Physical Activity and Sedentary Behavior in Community-Dwelling Men.

by Kota Fukai, Sei Harada, Miho Iida, Ayako Kurihara, Ayano Takeuchi, Kazuyo Kuwabara, Daisuke Sugiyama, Tomonori Okamura, Miki Akiyama, Yuji Nishiwaki, Yuko Oguma, Asako Suzuki, Chizuru Suzuki, Akiyoshi Hirayama, Masahiro Sugimoto, Tomoyoshi Soga, Masaru Tomita, Toru Takebayashi
Published 2016-01-01

Reliability of urinary charged metabolite concentrations in a large-scale cohort study using capillary electrophoresis-mass spectrometry

by Yoshiki Ishibashi, Sei Harada, Ayano Takeuchi, Miho Iida, Ayako Kurihara, Suzuka Kato, Kazuyo Kuwabara, Aya Hirata, Takuma Shibuki, Tomonori Okamura, Daisuke Sugiyama, Asako Sato, Kaori Amano, Akiyoshi Hirayama, Masahiro Sugimoto, Tomoyoshi Soga, Masaru Tomita, Toru Takebayashi
Published 2021-04-01