Accurate Classification of Protein Subcellular Localization from High-Throughput Microscopy Images Using Deep Learning

by Tanel Pärnamaa, Leopold Parts
Published 2017-05-01

A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies.

by Oliver Stegle, Leopold Parts, Richard Durbin, John Winn
Published 2010-05-01

Joint genetic analysis of gene expression data with inferred cellular phenotypes.

by Leopold Parts, Oliver Stegle, John Winn, Richard Durbin
Published 2011-01-01

Predicting quantitative traits from genome and phenome with near perfect accuracy

by Kaspar Märtens, Johan Hallin, Jonas Warringer, Gianni Liti, Leopold Parts
Published 2016-05-01

Prediction of antibiotic resistance in Escherichia coli from large-scale pan-genome data.

by Danesh Moradigaravand, Martin Palm, Anne Farewell, Ville Mustonen, Jonas Warringer, Leopold Parts
Published 2018-12-01

Inferring genome-wide recombination landscapes from advanced intercross lines: application to yeast crosses.

by Christopher J R Illingworth, Leopold Parts, Anders Bergström, Gianni Liti, Ville Mustonen
Published 2013-01-01

Genomic Epidemiology and Evolution of <i>Escherichia coli</i> in Wild Animals in Mexico

by Robert Murphy, Martin Palm, Ville Mustonen, Jonas Warringer, Anne Farewell, Leopold Parts, Danesh Moradigaravand
Published 2021-02-01

The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells

by Heather P Harding, Adriana Ordonez, Felicity Allen, Leopold Parts, Alison J Inglis, Roger L Williams, David Ron
Published 2019-11-01

Powerful decomposition of complex traits in a diploid model

by Johan Hallin, Kaspar Märtens, Alexander I. Young, Martin Zackrisson, Francisco Salinas, Leopold Parts, Jonas Warringer, Gianni Liti
Published 2016-11-01

Machine Learning Prediction of Resistance to Subinhibitory Antimicrobial Concentrations from <named-content content-type="genus-species">Escherichia coli</named-content> Genomes

by Sam Benkwitz-Bedford, Martin Palm, Talip Yasir Demirtas, Ville Mustonen, Anne Farewell, Jonas Warringer, Leopold Parts, Danesh Moradigaravand
Published 2021-08-01

Climate change at northern latitudes: rising atmospheric humidity decreases transpiration, N-uptake and growth rate of hybrid aspen.

by Arvo Tullus, Priit Kupper, Arne Sellin, Leopold Parts, Jaak Sõber, Tea Tullus, Krista Lõhmus, Anu Sõber, Hardi Tullus
Published 2012-01-01

Segregating YKU80 and TLC1 alleles underlying natural variation in telomere properties in wild yeast.

by Gianni Liti, Svasti Haricharan, Francisco A Cubillos, Anna L Tierney, Sarah Sharp, Alison A Bertuch, Leopold Parts, Elizabeth Bailes, Edward J Louis
Published 2009-09-01

The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis.

by Martijn van de Bunt, Kyle J Gaulton, Leopold Parts, Ignasi Moran, Paul R Johnson, Cecilia M Lindgren, Jorge Ferrer, Anna L Gloyn, Mark I McCarthy
Published 2013-01-01

Natural variants suppress mutations in hundreds of essential genes

by Leopold Parts, Amandine Batté, Maykel Lopes, Michael W Yuen, Meredith Laver, Bryan‐Joseph San Luis, Jia‐Xing Yue, Carles Pons, Elise Eray, Patrick Aloy, Gianni Liti, Jolanda vanLeeuwen
Published 2021-05-01

Minimal genome-wide human CRISPR-Cas9 library

by Emanuel Gonçalves, Mark Thomas, Fiona M. Behan, Gabriele Picco, Clare Pacini, Felicity Allen, Alessandro Vinceti, Mamta Sharma, David A. Jackson, Stacey Price, Charlotte M. Beaver, Oliver Dovey, David Parry-Smith, Francesco Iorio, Leopold Parts, Kosuke Yusa, Mathew J. Garnett
Published 2021-01-01

Patterns of cis regulatory variation in diverse human populations.

by Barbara E Stranger, Stephen B Montgomery, Antigone S Dimas, Leopold Parts, Oliver Stegle, Catherine E Ingle, Magda Sekowska, George Davey Smith, David Evans, Maria Gutierrez-Arcelus, Alkes Price, Towfique Raj, James Nisbett, Alexandra C Nica, Claude Beazley, Richard Durbin, Panos Deloukas, Emmanouil T Dermitzakis
Published 2012-01-01

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets

by Joshua M. Dempster, Clare Pacini, Sasha Pantel, Fiona M. Behan, Thomas Green, John Krill-Burger, Charlotte M. Beaver, Scott T. Younger, Victor Zhivich, Hanna Najgebauer, Felicity Allen, Emanuel Gonçalves, Rebecca Shepherd, John G. Doench, Kosuke Yusa, Francisca Vazquez, Leopold Parts, Jesse S. Boehm, Todd R. Golub, William C. Hahn, David E. Root, Mathew J. Garnett, Aviad Tsherniak, Francesco Iorio
Published 2019-12-01

Extent, causes, and consequences of small RNA expression variation in human adipose tissue.

by Leopold Parts, Åsa K Hedman, Sarah Keildson, Andrew J Knights, Cei Abreu-Goodger, Martijn van de Bunt, José Afonso Guerra-Assunção, Nenad Bartonicek, Stijn van Dongen, Reedik Mägi, James Nisbet, Amy Barrett, Mattias Rantalainen, Alexandra C Nica, Michael A Quail, Kerrin S Small, Daniel Glass, Anton J Enright, John Winn, MuTHER Consortium, Panos Deloukas, Emmanouil T Dermitzakis, Mark I McCarthy, Timothy D Spector, Richard Durbin, Cecilia M Lindgren
Published 2012-01-01

The architecture of gene regulatory variation across multiple human tissues: the MuTHER study.

by Alexandra C Nica, Leopold Parts, Daniel Glass, James Nisbet, Amy Barrett, Magdalena Sekowska, Mary Travers, Simon Potter, Elin Grundberg, Kerrin Small, Asa K Hedman, Veronique Bataille, Jordana Tzenova Bell, Gabriela Surdulescu, Antigone S Dimas, Catherine Ingle, Frank O Nestle, Paola di Meglio, Josine L Min, Alicja Wilk, Christopher J Hammond, Neelam Hassanali, Tsun-Po Yang, Stephen B Montgomery, Steve O'Rahilly, Cecilia M Lindgren, Krina T Zondervan, Nicole Soranzo, Inês Barroso, Richard Durbin, Kourosh Ahmadi, Panos Deloukas, Mark I McCarthy, Emmanouil T Dermitzakis, Timothy D Spector, MuTHER Consortium
Published 2011-02-01