Reconsidering association testing methods using single-variant test statistics as alternatives to pooling tests for sequence data with rare variants.

by Daniel D Kinnamon, Ray E Hershberger, Eden R Martin
Published 2012-01-01

Family-based association test using both common and rare variants and accounting for directions of effects for sequencing data.

by Ren-Hua Chung, Wei-Yun Tsai, Eden R Martin
Published 2014-01-01

A general framework for formal tests of interaction after exhaustive search methods with applications to MDR and MDR-PDT.

by Todd L Edwards, Stephen D Turner, Eric S Torstenson, Scott M Dudek, Eden R Martin, Marylyn D Ritchie
Published 2010-02-01

Impact of Genetic Ancestry on Prognostic Biomarkers in Uveal Melanoma

by Daniel A. Rodriguez, Margaret I. Sanchez, Christina L. Decatur, Zelia M. Correa, Eden R. Martin, J. William Harbour
Published 2020-10-01

Sex-specific DNA methylation differences in Alzheimer’s disease pathology

by Lanyu Zhang, Juan I. Young, Lissette Gomez, Tiago C. Silva, Michael A. Schmidt, Jesse Cai, Xi Chen, Eden R. Martin, Lily Wang
Published 2021-04-01

Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL.

by Udita Upadhyay, Gerald Z Zhuang, Luda Diatchenko, Marc Parisien, Yuan Kang, Konstantinos D Sarantopoulos, Eden R Martin, Shad B Smith, William Maixner, Roy C Levitt
Published 2019-06-01

Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease

by Lanyu Zhang, Tiago C. Silva, Juan I. Young, Lissette Gomez, Michael A. Schmidt, Kara L. Hamilton-Nelson, Brian W. Kunkle, Xi Chen, Eden R. Martin, Lily Wang
Published 2020-11-01

Genome-wide enriched pathway analysis of acute post-radiotherapy pain in breast cancer patients: a prospective cohort study

by Eunkyung Lee, Cristiane Takita, Jean L. Wright, Susan H. Slifer, Eden R. Martin, James J. Urbanic, Carl D. Langefeld, Glenn J. Lesser, Edward G. Shaw, Jennifer J. Hu
Published 2019-06-01

Identifying consensus disease pathways in Parkinson's disease using an integrative systems biology approach.

by Yvonne J K Edwards, Gary W Beecham, William K Scott, Sawsan Khuri, Guney Bademci, Demet Tekin, Eden R Martin, Zhijie Jiang, Deborah C Mash, Jarlath ffrench-Mullen, Margaret A Pericak-Vance, Nicholas Tsinoremas, Jeffery M Vance
Published 2011-02-01

Gene-Environment Interactions in Progressive Supranuclear Palsy

by Irene Litvan, James A. Proudfoot, Eden R. Martin, David Standaert, David Riley, Deborah Hall, Connie Marras, Ece Bayram, Richard M. Dubinsky, Yvette Bordelon, Stephen Reich, David Shprecher, David Shprecher, Benzi Kluger, Christopher Cunningham, Gerard D. Schellenberg, Joseph Jankovic
Published 2021-04-01

Convergence of miRNA expression profiling, α-synuclein interacton and GWAS in Parkinson's disease.

by Madalena Martins, Alexandra Rosa, Leonor C Guedes, Benedita V Fonseca, Kristina Gotovac, Sara Violante, Tiago Mestre, Miguel Coelho, Mário M Rosa, Eden R Martin, Jeffery M Vance, Tiago F Outeiro, Liyong Wang, Fran Borovecki, Joaquim J Ferreira, Sofia A Oliveira
Published 2011-01-01

Comparison of three targeted enrichment strategies on the SOLiD sequencing platform.

by Dale J Hedges, Toumy Guettouche, Shan Yang, Guney Bademci, Ashley Diaz, Ashley Andersen, William F Hulme, Sara Linker, Arpit Mehta, Yvonne J K Edwards, Gary W Beecham, Eden R Martin, Margaret A Pericak-Vance, Stephan Zuchner, Jeffery M Vance, John R Gilbert
Published 2011-04-01

Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway.

by Gerald Z Zhuang, Benjamin Keeler, Jeff Grant, Laura Bianchi, Eugene S Fu, Yan Ping Zhang, Diana M Erasso, Jian-Guo Cui, Tim Wiltshire, Qiongzhen Li, Shuanglin Hao, Konstantinos D Sarantopoulos, Keith Candiotti, Sarah M Wishnek, Shad B Smith, William Maixner, Luda Diatchenko, Eden R Martin, Roy C Levitt
Published 2015-01-01

Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.

by Adam C Naj, Gary W Beecham, Eden R Martin, Paul J Gallins, Eric H Powell, Ioanna Konidari, Patrice L Whitehead, Guiqing Cai, Vahram Haroutunian, William K Scott, Jeffery M Vance, Michael A Slifer, Harry E Gwirtsman, John R Gilbert, Jonathan L Haines, Joseph D Buxbaum, Margaret A Pericak-Vance
Published 2010-09-01

Reconstructing the population genetic history of the Caribbean.

by Andrés Moreno-Estrada, Simon Gravel, Fouad Zakharia, Jacob L McCauley, Jake K Byrnes, Christopher R Gignoux, Patricia A Ortiz-Tello, Ricardo J Martínez, Dale J Hedges, Richard W Morris, Celeste Eng, Karla Sandoval, Suehelay Acevedo-Acevedo, Paul J Norman, Zulay Layrisse, Peter Parham, Juan Carlos Martínez-Cruzado, Esteban González Burchard, Michael L Cuccaro, Eden R Martin, Carlos D Bustamante
Published 2013-11-01

Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.

by Farid Rajabli, Briseida E Feliciano, Katrina Celis, Kara L Hamilton-Nelson, Patrice L Whitehead, Larry D Adams, Parker L Bussies, Clara P Manrique, Alejandra Rodriguez, Vanessa Rodriguez, Takiyah Starks, Grace E Byfield, Carolina B Sierra Lopez, Jacob L McCauley, Heriberto Acosta, Angel Chinea, Brian W Kunkle, Christiane Reitz, Lindsay A Farrer, Gerard D Schellenberg, Badri N Vardarajan, Jeffery M Vance, Michael L Cuccaro, Eden R Martin, Jonathan L Haines, Goldie S Byrd, Gary W Beecham, Margaret A Pericak-Vance
Published 2018-12-01

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.

by Gary W Beecham, Kara Hamilton, Adam C Naj, Eden R Martin, Matt Huentelman, Amanda J Myers, Jason J Corneveaux, John Hardy, Jean-Paul Vonsattel, Steven G Younkin, David A Bennett, Philip L De Jager, Eric B Larson, Paul K Crane, M Ilyas Kamboh, Julia K Kofler, Deborah C Mash, Linda Duque, John R Gilbert, Harry Gwirtsman, Joseph D Buxbaum, Patricia Kramer, Dennis W Dickson, Lindsay A Farrer, Matthew P Frosch, Bernardino Ghetti, Jonathan L Haines, Bradley T Hyman, Walter A Kukull, Richard P Mayeux, Margaret A Pericak-Vance, Julie A Schneider, John Q Trojanowski, Eric M Reiman, Alzheimer's Disease Genetics Consortium (ADGC), Gerard D Schellenberg, Thomas J Montine
Published 2014-09-01

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.

by Christina M Lill, Johannes T Roehr, Matthew B McQueen, Fotini K Kavvoura, Sachin Bagade, Brit-Maren M Schjeide, Leif M Schjeide, Esther Meissner, Ute Zauft, Nicole C Allen, Tian Liu, Marcel Schilling, Kari J Anderson, Gary Beecham, Daniela Berg, Joanna M Biernacka, Alexis Brice, Anita L DeStefano, Chuong B Do, Nicholas Eriksson, Stewart A Factor, Matthew J Farrer, Tatiana Foroud, Thomas Gasser, Taye Hamza, John A Hardy, Peter Heutink, Erin M Hill-Burns, Christine Klein, Jeanne C Latourelle, Demetrius M Maraganore, Eden R Martin, Maria Martinez, Richard H Myers, Michael A Nalls, Nathan Pankratz, Haydeh Payami, Wataru Satake, William K Scott, Manu Sharma, Andrew B Singleton, Kari Stefansson, Tatsushi Toda, Joyce Y Tung, Jeffery Vance, Nick W Wood, Cyrus P Zabetian, 23andMe Genetic Epidemiology of Parkinson's Disease Consortium, International Parkinson's Disease Genomics Consortium, Parkinson's Disease GWAS Consortium, Wellcome Trust Case Control Consortium 2), Peter Young, Rudolph E Tanzi, Muin J Khoury, Frauke Zipp, Hans Lehrach, John P A Ioannidis, Lars Bertram
Published 2012-01-01

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

by Valentina Escott-Price, Céline Bellenguez, Li-San Wang, Seung-Hoan Choi, Denise Harold, Lesley Jones, Peter Holmans, Amy Gerrish, Alexey Vedernikov, Alexander Richards, Anita L DeStefano, Jean-Charles Lambert, Carla A Ibrahim-Verbaas, Adam C Naj, Rebecca Sims, Gyungah Jun, Joshua C Bis, Gary W Beecham, Benjamin Grenier-Boley, Giancarlo Russo, Tricia A Thornton-Wells, Nicola Denning, Albert V Smith, Vincent Chouraki, Charlene Thomas, M Arfan Ikram, Diana Zelenika, Badri N Vardarajan, Yoichiro Kamatani, Chiao-Feng Lin, Helena Schmidt, Brian Kunkle, Melanie L Dunstan, Maria Vronskaya, United Kingdom Brain Expression Consortium, Andrew D Johnson, Agustin Ruiz, Marie-Thérèse Bihoreau, Christiane Reitz, Florence Pasquier, Paul Hollingworth, Olivier Hanon, Annette L Fitzpatrick, Joseph D Buxbaum, Dominique Campion, Paul K Crane, Clinton Baldwin, Tim Becker, Vilmundur Gudnason, Carlos Cruchaga, David Craig, Najaf Amin, Claudine Berr, Oscar L Lopez, Philip L De Jager, Vincent Deramecourt, Janet A Johnston, Denis Evans, Simon Lovestone, Luc Letenneur, Isabel Hernández, David C Rubinsztein, Gudny Eiriksdottir, Kristel Sleegers, Alison M Goate, Nathalie Fiévet, Matthew J Huentelman, Michael Gill, Kristelle Brown, M Ilyas Kamboh, Lina Keller, Pascale Barberger-Gateau, Bernadette McGuinness, Eric B Larson, Amanda J Myers, Carole Dufouil, Stephen Todd, David Wallon, Seth Love, Ekaterina Rogaeva, John Gallacher, Peter St George-Hyslop, Jordi Clarimon, Alberto Lleo, Anthony Bayer, Debby W Tsuang, Lei Yu, Magda Tsolaki, Paola Bossù, Gianfranco Spalletta, Petra Proitsi, John Collinge, Sandro Sorbi, Florentino Sanchez Garcia, Nick C Fox, John Hardy, Maria Candida Deniz Naranjo, Paolo Bosco, Robert Clarke, Carol Brayne, Daniela Galimberti, Elio Scarpini, Ubaldo Bonuccelli, Michelangelo Mancuso, Gabriele Siciliano, Susanne Moebus, Patrizia Mecocci, Maria Del Zompo, Wolfgang Maier, Harald Hampel, Alberto Pilotto, Ana Frank-García, Francesco Panza, Vincenzo Solfrizzi, Paolo Caffarra, Benedetta Nacmias, William Perry, Manuel Mayhaus, Lars Lannfelt, Hakon Hakonarson, Sabrina Pichler, Minerva M Carrasquillo, Martin Ingelsson, Duane Beekly, Victoria Alvarez, Fanggeng Zou, Otto Valladares, Steven G Younkin, Eliecer Coto, Kara L Hamilton-Nelson, Wei Gu, Cristina Razquin, Pau Pastor, Ignacio Mateo, Michael J Owen, Kelley M Faber, Palmi V Jonsson, Onofre Combarros, Michael C O'Donovan, Laura B Cantwell, Hilkka Soininen, Deborah Blacker, Simon Mead, Thomas H Mosley, David A Bennett, Tamara B Harris, Laura Fratiglioni, Clive Holmes, Renee F A G de Bruijn, Peter Passmore, Thomas J Montine, Karolien Bettens, Jerome I Rotter, Alexis Brice, Kevin Morgan, Tatiana M Foroud, Walter A Kukull, Didier Hannequin, John F Powell, Michael A Nalls, Karen Ritchie, Kathryn L Lunetta, John S K Kauwe, Eric Boerwinkle, Matthias Riemenschneider, Mercè Boada, Mikko Hiltunen, Eden R Martin, Reinhold Schmidt, Dan Rujescu, Jean-François Dartigues, Richard Mayeux, Christophe Tzourio, Albert Hofman, Markus M Nöthen, Caroline Graff, Bruce M Psaty, Jonathan L Haines, Mark Lathrop, Margaret A Pericak-Vance, Lenore J Launer, Christine Van Broeckhoven, Lindsay A Farrer, Cornelia M van Duijn, Alfredo Ramirez, Sudha Seshadri, Gerard D Schellenberg, Philippe Amouyel, Julie Williams, Cardiovascular Health Study (CHS)
Published 2014-01-01