Serum neurofilament light levels correlate with severity measures and neurodegeneration markers in autosomal dominant Alzheimer’s disease

by Raquel Sánchez-Valle, Amanda Heslegrave, Martha S. Foiani, Beatriz Bosch, Anna Antonell, Mircea Balasa, Albert Lladó, Henrik Zetterberg, Nick C. Fox
Published 2018-11-01

The importance of group-wise registration in tract based spatial statistics study of neurodegeneration: a simulation study in Alzheimer's disease.

by Shiva Keihaninejad, Natalie S Ryan, Ian B Malone, Marc Modat, David Cash, Gerard R Ridgway, Hui Zhang, Nick C Fox, Sebastien Ourselin
Published 2012-01-01

APOE ε4 is associated with disproportionate progressive hippocampal atrophy in AD.

by Emily N Manning, Josephine Barnes, David M Cash, Jonathan W Bartlett, Kelvin K Leung, Sebastien Ourselin, Nick C Fox, Alzheimer's Disease NeuroImaging Initiative
Published 2014-01-01

Eye-tracking indices of impaired encoding of visual short-term memory in familial Alzheimer’s disease

by Ivanna M. Pavisic, Yoni Pertzov, Jennifer M. Nicholas, Antoinette O’Connor, Kirsty Lu, Keir X. X. Yong, Masud Husain, Nick C. Fox, Sebastian J. Crutch
Published 2021-04-01

Quantitative detection and staging of presymptomatic cognitive decline in familial Alzheimer’s disease: a retrospective cohort analysis

by Antoinette O’Connor, Philip S. J. Weston, Ivanna M. Pavisic, Natalie S. Ryan, Jessica D. Collins, Kirsty Lu, Sebastian J. Crutch, Daniel C. Alexander, Nick C. Fox, Neil P. Oxtoby
Published 2020-10-01

Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer’s disease

by Philip S. J. Weston, Teresa Poole, Antoinette O’Connor, Amanda Heslegrave, Natalie S. Ryan, Yuying Liang, Ronald Druyeh, Simon Mead, Kaj Blennow, Jonathan M. Schott, Chris Frost, Henrik Zetterberg, Nick C. Fox
Published 2019-02-01

ApoE4 lowers age at onset in patients with frontotemporal dementia and tauopathy independent of amyloid‐β copathology

by Carolin Koriath, Tammaryn Lashley, William Taylor, Ronald Druyeh, Athanasios Dimitriadis, Nicola Denning, Julie Williams, Jason D. Warren, Nick C. Fox, Jonathan M. Schott, James B. Rowe, John Collinge, Jonathan D. Rohrer, Simon Mead
Published 2019-12-01

CSF synaptic protein concentrations are raised in those with atypical Alzheimer’s disease but not frontotemporal dementia

by Mica T. M. Clarke, Ann Brinkmalm, Martha S. Foiani, Ione O. C. Woollacott, Carolin Heller, Amanda Heslegrave, Ashvini Keshavan, Nick C. Fox, Jonathan M. Schott, Jason D. Warren, Kaj Blennow, Henrik Zetterberg, Jonathan D. Rohrer
Published 2019-12-01

Familial Alzheimer’s Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis

by Charles Arber, Christopher Lovejoy, Lachlan Harris, Nanet Willumsen, Argyro Alatza, Jackie M. Casey, Georgie Lines, Caoimhe Kerins, Anika K. Mueller, Henrik Zetterberg, John Hardy, Natalie S. Ryan, Nick C. Fox, Tammaryn Lashley, Selina Wray
Published 2021-01-01

Measuring cortical mean diffusivity to assess early microstructural cortical change in presymptomatic familial Alzheimer’s disease

by Philip S. J. Weston, Teresa Poole, Jennifer M. Nicholas, Nicolas Toussaint, Ivor J. A. Simpson, Marc Modat, Natalie S. Ryan, Yuying Liang, Martin N. Rossor, Jonathan M. Schott, Sebastien Ourselin, Hui Zhang, Nick C. Fox
Published 2020-09-01

White matter tract signatures of impaired social cognition in frontotemporal lobar degeneration

by Laura E. Downey, Colin J. Mahoney, Aisling H. Buckley, Hannah L. Golden, Susie M. Henley, Nicole Schmitz, Jonathan M. Schott, Ivor J. Simpson, Sebastien Ourselin, Nick C. Fox, Sebastian J. Crutch, Jason D. Warren
Published 2015-01-01

Genetic variability in CLU and its association with Alzheimer's disease.

by Rita J Guerreiro, John Beck, J Raphael Gibbs, Isabel Santana, Martin N Rossor, Jonathan M Schott, Michael A Nalls, Helena Ribeiro, Beatriz Santiago, Nick C Fox, Catarina Oliveira, John Collinge, Simon Mead, Andrew Singleton, John Hardy
Published 2010-03-01

Study Protocol – Insight 46 Cardiovascular: A Sub-study of the MRC National Survey of Health and Development

by Sarah Ann Mason, Lamia Al Saikhan, Siana Jones, Gemma Bale, Sarah-Naomi James, Heidi Murray-Smith, Alicja Rapala, Suzanne Williams, Brian Wong, Marcus Richards, Nick C. Fox, Rebecca Hardy, Jonathan M. Schott, Nish Chaturvedi, Alun D. Hughes
Published 2020-04-01

Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup

by Ione O. C. Woollacott, Jennifer M. Nicholas, Amanda Heslegrave, Carolin Heller, Martha S. Foiani, Katrina M. Dick, Lucy L. Russell, Ross W. Paterson, Ashvini Keshavan, Nick C. Fox, Jason D. Warren, Jonathan M. Schott, Henrik Zetterberg, Jonathan D. Rohrer
Published 2018-08-01

Using a birth cohort to study brain health and preclinical dementia: recruitment and participation rates in Insight 46

by Sarah-Naomi James, Christopher A. Lane, Thomas D. Parker, Kirsty Lu, Jessica D. Collins, Heidi Murray-Smith, Michelle Byford, Andrew Wong, Ashvini Keshavan, Sarah Buchanan, Sarah E. Keuss, Diana Kuh, Nick C. Fox, Jonathan M. Schott, Marcus Richards
Published 2018-12-01

Differences in hippocampal subfield volume are seen in phenotypic variants of early onset Alzheimer's disease

by Thomas D. Parker, Catherine F. Slattery, Keir X.X. Yong, Jennifer M. Nicholas, Ross W. Paterson, Alexander J.M. Foulkes, Ian B. Malone, David L. Thomas, David M. Cash, Sebastian J. Crutch, Nick C. Fox, Jonathan M. Schott
Published 2019-01-01

Atrophy rates in asymptomatic amyloidosis: implications for Alzheimer prevention trials.

by K Abigail Andrews, Marc Modat, Kate E Macdonald, Tom Yeatman, M Jorge Cardoso, Kelvin K Leung, Josephine Barnes, Victor L Villemagne, Christopher C Rowe, Nick C Fox, Sebastien Ourselin, Jonathan M Schott, Australian Imaging Biomarkers, Lifestyle Flagship Study of Ageing
Published 2013-01-01

Do cerebrospinal fluid transfer methods affect measured amyloid β42, total tau, and phosphorylated tau in clinical practice?

by Ross W. Paterson, Jamie Toombs, Miles D. Chapman, Jennifer M. Nicholas, Amanda J. Heslegrave, Catherine F. Slattery, Alexander J.M. Foulkes, Camilla N. Clark, Christopher A.S. Lane, Philip S.J. Weston, Michael P. Lunn, Nick C. Fox, Henrik Zetterberg, Jonathan M. Schott
Published 2015-09-01

Inhibiting the Ca2+ Influx Induced by Human CSF

by Anna Drews, Suman De, Patrick Flagmeier, David C. Wirthensohn, Wei-Hsin Chen, Daniel R. Whiten, Margarida Rodrigues, Cécile Vincke, Serge Muyldermans, Ross W. Paterson, Catherine F. Slattery, Nick C. Fox, Jonathan M. Schott, Henrik Zetterberg, Christopher M. Dobson, Sonia Gandhi, David Klenerman
Published 2017-12-01

Concordance of CSF measures of Alzheimer's pathology with amyloid PET status in a preclinical cohort: A comparison of Lumipulse and established immunoassays

by Ashvini Keshavan, Henrietta Wellington, Zhongbo Chen, Ayesha Khatun, Miles Chapman, Melanie Hart, David M. Cash, William Coath, Thomas D. Parker, Sarah M. Buchanan, Sarah E. Keuss, Matthew J. Harris, Heidi Murray‐Smith, Amanda Heslegrave, Nick C. Fox, Henrik Zetterberg, Jonathan M. Schott
Published 2020-01-01