The retinoic acid receptor beta (Rarb) region of Mmu14 is associated with prion disease incubation time in mouse.

by Julia Grizenkova, Shaheen Akhtar, John Collinge, Sarah E Lloyd
Published 2010-12-01

Sex effects in mouse prion disease incubation time.

by Shaheen Akhtar, Adam Wenborn, Sebastian Brandner, John Collinge, Sarah E Lloyd
Published 2011-01-01

Hippocampal bursts caused by changes in NMDA receptor-dependent excitation in a mouse model of variant CJD

by Stéphanie Ratté, Steven A. Prescott, John Collinge, John G.R. Jefferys
Published 2008-10-01

Case report of homozygous E200D mutation of PRNP in apparently sporadic Creutzfeldt-Jakob disease

by Ahamad Hassan, Tracy Campbell, Lee Darwent, Hans Odd, Alison Green, John Collinge, Simon Mead
Published 2021-06-01

The language disorder of prion disease is characteristic of a dynamic aphasia and is rarely an isolated clinical feature.

by Diana Caine, Akin Nihat, Philippa Crabb, Peter Rudge, Lisa Cipolotti, John Collinge, Simon Mead
Published 2018-01-01

Superoxide dismutase 1 and tgSOD1 mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosis.

by Ruth Chia, M Howard Tattum, Samantha Jones, John Collinge, Elizabeth M C Fisher, Graham S Jackson
Published 2010-05-01

Familial Creutzfeldt-Jakob disease in an Indian kindred

by Sarosh M Katrak, Apoorva Pauranik, Shrinivas B Desai, Simon Mead, Jon Beck, Sebastian Brandner, John Collinge
Published 2019-01-01

Isolation of proteinase K-sensitive prions using pronase E and phosphotungstic acid.

by Laura D'Castro, Adam Wenborn, Nathalie Gros, Susan Joiner, Sabrina Cronier, John Collinge, Jonathan D F Wadsworth
Published 2010-12-01

Bank vole prion protein extends the use of RT-QuIC assays to detect prions in a range of inherited prion diseases

by Tze How Mok, Akin Nihat, Connie Luk, Danielle Sequeira, Mark Batchelor, Simon Mead, John Collinge, Graham S. Jackson
Published 2021-03-01

Sod1 deficiency reduces incubation time in mouse models of prion disease.

by Shaheen Akhtar, Julia Grizenkova, Adam Wenborn, Holger Hummerich, Mar Fernandez de Marco, Sebastian Brandner, John Collinge, Sarah E Lloyd
Published 2013-01-01

Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection.

by Rocio Castro-Seoane, Holger Hummerich, Trevor Sweeting, M Howard Tattum, Jacqueline M Linehan, Mar Fernandez de Marco, Sebastian Brandner, John Collinge, Peter-Christian Klöhn
Published 2012-02-01

HECTD2 is associated with susceptibility to mouse and human prion disease.

by Sarah E Lloyd, Emma G Maytham, Hirva Pota, Julia Grizenkova, Eleni Molou, James Uphill, Holger Hummerich, Jerome Whitfield, Michael P Alpers, Simon Mead, John Collinge
Published 2009-02-01

Soluble Aβ aggregates can inhibit prion propagation

by Claire J. Sarell, Emma Quarterman, Daniel C.-M. Yip, Cassandra Terry, Andrew J. Nicoll, Jonathan D. F. Wadsworth, Mark A. Farrow, Dominic M. Walsh, John Collinge
Published 2017-01-01

Video Rating in Neurodegenerative Disease Clinical Trials: The Experience of PRION-1

by Christopher Carswell, Michael Rañopa, Suvankar Pal, Rebecca MacFarlane, Durre Siddique, Dafydd Thomas, Tom Webb, Steve Wroe, Sarah Walker, Janet Darbyshire, John Collinge, Simon Mead, Peter Rudge
Published 2012-08-01

Inherited prion disease A117V is not simply a proteinopathy but produces prions transmissible to transgenic mice expressing homologous prion protein.

by Emmanuel A Asante, Jacqueline M Linehan, Michelle Smidak, Andrew Tomlinson, Andrew Grimshaw, Asif Jeelani, Tatiana Jakubcova, Shyma Hamdan, Caroline Powell, Sebastian Brandner, Jonathan D F Wadsworth, John Collinge
Published 2013-01-01

A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis

by Penny J. Norsworthy, Andrew G. B. Thompson, Tze H. Mok, Fernando Guntoro, Luke C. Dabin, Akin Nihat, Ross W. Paterson, Jonathan M. Schott, John Collinge, Simon Mead, Emmanuelle A. Viré
Published 2020-08-01

Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS.

by Emmanuel A Asante, Jacqueline M Linehan, Andrew Tomlinson, Tatiana Jakubcova, Shyma Hamdan, Andrew Grimshaw, Michelle Smidak, Asif Jeelani, Akin Nihat, Simon Mead, Sebastian Brandner, Jonathan D F Wadsworth, John Collinge
Published 2020-06-01

Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS.

by Emmanuel A Asante, Andrew Grimshaw, Michelle Smidak, Tatiana Jakubcova, Andrew Tomlinson, Asif Jeelani, Shyma Hamdan, Caroline Powell, Susan Joiner, Jacqueline M Linehan, Sebastian Brandner, Jonathan D F Wadsworth, John Collinge
Published 2015-07-01

Neuroanatomical correlates of prion disease progression - a 3T longitudinal voxel-based morphometry study

by Enrico De Vita, Gerard R Ridgway, Mark J White, Marie-Claire Porter, Diana Caine, Peter Rudge, John Collinge, Tarek A Yousry, Hans Rolf Jager, Simon Mead, John S Thornton, Harpreet Hyare
Published 2017-01-01

Ex vivo mammalian prions are formed of paired double helical prion protein fibrils

by Cassandra Terry, Adam Wenborn, Nathalie Gros, Jessica Sells, Susan Joiner, Laszlo L. P. Hosszu, M. Howard Tattum, Silvia Panico, Daniel K. Clare, John Collinge, Helen R. Saibil, Jonathan D. F. Wadsworth
Published 2016-01-01