Jointly Modelling Single Nucleotide Polymorphisms With Longitudinal and Time-to-Event Trait: An Application to Type 2 Diabetes and Fasting Plasma Glucose

by Mickaël Canouil, Mickaël Canouil, Mickaël Canouil, Beverley Balkau, Beverley Balkau, Beverley Balkau, Ronan Roussel, Ronan Roussel, Ronan Roussel, Philippe Froguel, Philippe Froguel, Philippe Froguel, Philippe Froguel, Ghislain Rocheleau, Ghislain Rocheleau, Ghislain Rocheleau
Published 2018-06-01

Association between fasting glucose and all-cause mortality according to sex and age: a prospective cohort study

by Sang-Wook Yi, Sangkyu Park, Yong-ho Lee, Hyang-Jeong Park, Beverley Balkau, Jee-Jeon Yi
Published 2017-08-01

Insulin pricing and other major diabetes-related concerns in the USA: a study of 46 407 tweets between 2017 and 2019

by Adrian Ahne, Francisco Orchard, Xavier Tannier, Camille Perchoux, Beverley Balkau, Sherry Pagoto, Jessica Lee Harding, Thomas Czernichow
Published 2020-04-01

Type 2 diabetes and its characteristics are associated with poor oral health: findings from 60,590 senior women from the E3N study

by Nasser Laouali, Douae El Fatouhi, Gloria Aguayo, Beverley Balkau, Marie-Christine Boutron-Ruault, Fabrice Bonnet, Guy Fagherazzi
Published 2021-06-01

Renal function markers and insulin sensitivity after 3 years in a healthy cohort, the EGIR-RISC study

by Soline Siméon, Ziad Massy, Kurt Højlund, Katarina Lalic, Francesca Porcellati, Jacqueline Dekker, John Petrie, Gemma Currie, Beverley Balkau
Published 2018-05-01

Impact of statistical models on the prediction of type 2 diabetes using non-targeted metabolomics profiling

by Loic Yengo, Abdelilah Arredouani, Michel Marre, Ronan Roussel, Martine Vaxillaire, Mario Falchi, Abdelali Haoudi, Jean Tichet, Beverley Balkau, Amélie Bonnefond, Philippe Froguel
Published 2016-10-01

Home and Work Physical Activity Environments: Associations with Cardiorespiratory Fitness and Physical Activity Level in French Women

by Jean-Michel Oppert, Marie-Aline Charles, Hélène Charreire, Mehdi Menai, Ilse De Bourdeaudhuij, Soren Brage, Blandine de Lauzon-Guillain, Guy Fagherazzi, Beverley Balkau
Published 2016-08-01

Blood microbiota dysbiosis is associated with the onset of cardiovascular events in a large general population: the D.E.S.I.R. study.

by Jacques Amar, Céline Lange, Gaëlle Payros, Celine Garret, Chantal Chabo, Olivier Lantieri, Michael Courtney, Michel Marre, Marie Aline Charles, Beverley Balkau, Rémy Burcelin, D.E.S.I.R. Study Group
Published 2013-01-01

Non-laboratory-based self-assessment screening score for non-alcoholic fatty liver disease: development, validation and comparison with other scores.

by Yong-ho Lee, Heejung Bang, Young Min Park, Ji Cheol Bae, Byung-Wan Lee, Eun Seok Kang, Bong Soo Cha, Hyun Chul Lee, Beverley Balkau, Won-Young Lee, Dae Jung Kim
Published 2014-01-01

Glucose-dependent regulation of NR2F2 promoter and influence of SNP-rs3743462 on whole body insulin sensitivity.

by Marie Boutant, Oscar Henrique Pereira Ramos, Cécile Lecoeur, Emmanuel Vaillant, Julien Philippe, Pili Zhang, Anaïs Perilhou, Beatriz Valcarcel, Sylvain Sebert, Mario-Ritta Jarvelin, Beverley Balkau, Donald Scott, Philippe Froguel, Martine Vaxillaire, Mireille Vasseur-Cognet
Published 2012-01-01

New roles for prokineticin 2 in feeding behavior, insulin resistance and type 2 diabetes: Studies in mice and humans

by Marie Mortreux, Ewout Foppen, Raphaël G. Denis, Mireia Montaner, Nadim Kassis, Jessica Denom, Mylène Vincent, Frédéric Fumeron, Margaux Kujawski-Lafourcade, Fabrizio Andréelli, Beverley Balkau, Michel Marre, Ronan Roussel, Christophe Magnan, Hirac Gurden, Stéphanie Migrenne-Li
Published 2019-11-01

Whole-exome sequencing and high throughput genotyping identified KCNJ11 as the thirteenth MODY gene.

by Amélie Bonnefond, Julien Philippe, Emmanuelle Durand, Aurélie Dechaume, Marlène Huyvaert, Louise Montagne, Michel Marre, Beverley Balkau, Isabelle Fajardy, Anne Vambergue, Vincent Vatin, Jérôme Delplanque, David Le Guilcher, Franck De Graeve, Cécile Lecoeur, Olivier Sand, Martine Vaxillaire, Philippe Froguel
Published 2012-01-01

What is the contribution of two genetic variants regulating VEGF levels to type 2 diabetes risk and to microvascular complications?

by Amélie Bonnefond, Pierre-Jean Saulnier, Maria G Stathopoulou, Niels Grarup, Ndeye Coumba Ndiaye, Ronan Roussel, Mohsen Azimi Nezhad, Aurélie Dechaume, Olivier Lantieri, Serge Hercberg, Torsten Lauritzen, Beverley Balkau, Julia S El-Sayed Moustafa, Torben Hansen, Oluf Pedersen, Philippe Froguel, Guillaume Charpentier, Michel Marre, Samy Hadjadj, Sophie Visvikis-Siest
Published 2013-01-01

Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value.

by Stéphane Cauchi, David Meyre, Emmanuelle Durand, Christine Proença, Michel Marre, Samy Hadjadj, Hélène Choquet, Franck De Graeve, Stefan Gaget, Frederic Allegaert, Jérôme Delplanque, Marshall Alan Permutt, Jon Wasson, Ilana Blech, Guillaume Charpentier, Beverley Balkau, Anne-Claire Vergnaud, Sébastien Czernichow, Wolfgang Patsch, Mohamed Chikri, Benjamin Glaser, Robert Sladek, Philippe Froguel
Published 2008-05-01

Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity.

by Robin G Walters, Lachlan J M Coin, Aimo Ruokonen, Adam J de Smith, Julia S El-Sayed Moustafa, Sebastien Jacquemont, Paul Elliott, Tõnu Esko, Anna-Liisa Hartikainen, Jaana Laitinen, Katrin Männik, Danielle Martinet, David Meyre, Matthias Nauck, Claudia Schurmann, Rob Sladek, Gudmar Thorleifsson, Unnur Thorsteinsdóttir, Armand Valsesia, Gerard Waeber, Flore Zufferey, Beverley Balkau, François Pattou, Andres Metspalu, Henry Völzke, Peter Vollenweider, Kári Stefansson, Marjo-Riitta Järvelin, Jacques S Beckmann, Philippe Froguel, Alexandra I F Blakemore
Published 2013-01-01

A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes: The EPIC-InterAct case-cohort study.

by Fumiaki Imamura, Stephen J Sharp, Albert Koulman, Matthias B Schulze, Janine Kröger, Julian L Griffin, José M Huerta, Marcela Guevara, Ivonne Sluijs, Antonio Agudo, Eva Ardanaz, Beverley Balkau, Heiner Boeing, Veronique Chajes, Christina C Dahm, Courtney Dow, Guy Fagherazzi, Edith J M Feskens, Paul W Franks, Diana Gavrila, Marc Gunter, Rudolf Kaaks, Timothy J Key, Kay-Tee Khaw, Tilman Kühn, Olle Melander, Elena Molina-Portillo, Peter M Nilsson, Anja Olsen, Kim Overvad, Domenico Palli, Salvatore Panico, Olov Rolandsson, Sabina Sieri, Carlotta Sacerdote, Nadia Slimani, Annemieke M W Spijkerman, Anne Tjønneland, Rosario Tumino, Yvonne T van der Schouw, Claudia Langenberg, Elio Riboli, Nita G Forouhi, Nick J Wareham
Published 2017-10-01

Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.

by André Scherag, Christian Dina, Anke Hinney, Vincent Vatin, Susann Scherag, Carla I G Vogel, Timo D Müller, Harald Grallert, H-Erich Wichmann, Beverley Balkau, Barbara Heude, Marjo-Riitta Jarvelin, Anna-Liisa Hartikainen, Claire Levy-Marchal, Jacques Weill, Jérôme Delplanque, Antje Körner, Wieland Kiess, Peter Kovacs, Nigel W Rayner, Inga Prokopenko, Mark I McCarthy, Helmut Schäfer, Ivonne Jarick, Heiner Boeing, Eva Fisher, Thomas Reinehr, Joachim Heinrich, Peter Rzehak, Dietrich Berdel, Michael Borte, Heike Biebermann, Heiko Krude, Dieter Rosskopf, Christian Rimmbach, Winfried Rief, Tobias Fromme, Martin Klingenspor, Annette Schürmann, Nadja Schulz, Markus M Nöthen, Thomas W Mühleisen, Raimund Erbel, Karl-Heinz Jöckel, Susanne Moebus, Tanja Boes, Thomas Illig, Philippe Froguel, Johannes Hebebrand, David Meyre
Published 2010-04-01

Long-term risk of incident type 2 diabetes and measures of overall and regional obesity: the EPIC-InterAct case-cohort study.

by InterAct Consortium, Claudia Langenberg, Stephen J Sharp, Matthias B Schulze, Olov Rolandsson, Kim Overvad, Nita G Forouhi, Joachim Spranger, Dagmar Drogan, José María Huerta, Larraitz Arriola, Blandine de Lauzon-Guillan, Maria-Jose Tormo, Eva Ardanaz, Beverley Balkau, Joline W J Beulens, Heiner Boeing, H Bas Bueno-de-Mesquita, Françoise Clavel-Chapelon, Francesca L Crowe, Paul W Franks, Carlos A Gonzalez, Sara Grioni, Jytte Halkjaer, Goran Hallmans, Rudolf Kaaks, Nicola D Kerrison, Timothy J Key, Kay Tee Khaw, Amalia Mattiello, Peter Nilsson, Teresa Norat, Luigi Palla, Domenico Palli, Salvatore Panico, J Ramón Quirós, Dora Romaguera, Isabelle Romieu, Carlotta Sacerdote, María-José Sánchez, Nadia Slimani, Ivonne Sluijs, Annemieke M W Spijkerman, Birgit Teucher, Anne Tjonneland, Rosario Tumino, Daphne L van der A, Yvonne T van der Schouw, Edith J M Feskens, Elio Riboli, Nicholas J Wareham
Published 2012-01-01

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.

by John R B Perry, Benjamin F Voight, Loïc Yengo, Najaf Amin, Josée Dupuis, Martha Ganser, Harald Grallert, Pau Navarro, Man Li, Lu Qi, Valgerdur Steinthorsdottir, Robert A Scott, Peter Almgren, Dan E Arking, Yurii Aulchenko, Beverley Balkau, Rafn Benediktsson, Richard N Bergman, Eric Boerwinkle, Lori Bonnycastle, Noël P Burtt, Harry Campbell, Guillaume Charpentier, Francis S Collins, Christian Gieger, Todd Green, Samy Hadjadj, Andrew T Hattersley, Christian Herder, Albert Hofman, Andrew D Johnson, Anna Kottgen, Peter Kraft, Yann Labrune, Claudia Langenberg, Alisa K Manning, Karen L Mohlke, Andrew P Morris, Ben Oostra, James Pankow, Ann-Kristin Petersen, Peter P Pramstaller, Inga Prokopenko, Wolfgang Rathmann, William Rayner, Michael Roden, Igor Rudan, Denis Rybin, Laura J Scott, Gunnar Sigurdsson, Rob Sladek, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Jaakko Tuomilehto, Andre G Uitterlinden, Sidonie Vivequin, Michael N Weedon, Alan F Wright, MAGIC, DIAGRAM Consortium, GIANT Consortium, Frank B Hu, Thomas Illig, Linda Kao, James B Meigs, James F Wilson, Kari Stefansson, Cornelia van Duijn, David Altschuler, Andrew D Morris, Michael Boehnke, Mark I McCarthy, Philippe Froguel, Colin N A Palmer, Nicholas J Wareham, Leif Groop, Timothy M Frayling, Stéphane Cauchi
Published 2012-05-01

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.

by Tuomas O Kilpeläinen, Lu Qi, Soren Brage, Stephen J Sharp, Emily Sonestedt, Ellen Demerath, Tariq Ahmad, Samia Mora, Marika Kaakinen, Camilla Helene Sandholt, Christina Holzapfel, Christine S Autenrieth, Elina Hyppönen, Stéphane Cauchi, Meian He, Zoltan Kutalik, Meena Kumari, Alena Stančáková, Karina Meidtner, Beverley Balkau, Jonathan T Tan, Massimo Mangino, Nicholas J Timpson, Yiqing Song, M Carola Zillikens, Kathleen A Jablonski, Melissa E Garcia, Stefan Johansson, Jennifer L Bragg-Gresham, Ying Wu, Jana V van Vliet-Ostaptchouk, N Charlotte Onland-Moret, Esther Zimmermann, Natalia V Rivera, Toshiko Tanaka, Heather M Stringham, Günther Silbernagel, Stavroula Kanoni, Mary F Feitosa, Soren Snitker, Jonatan R Ruiz, Jeffery Metter, Maria Teresa Martinez Larrad, Mustafa Atalay, Maarit Hakanen, Najaf Amin, Christine Cavalcanti-Proença, Anders Grøntved, Göran Hallmans, John-Olov Jansson, Johanna Kuusisto, Mika Kähönen, Pamela L Lutsey, John J Nolan, Luigi Palla, Oluf Pedersen, Louis Pérusse, Frida Renström, Robert A Scott, Dmitry Shungin, Ulla Sovio, Tuija H Tammelin, Tapani Rönnemaa, Timo A Lakka, Matti Uusitupa, Manuel Serrano Rios, Luigi Ferrucci, Claude Bouchard, Aline Meirhaeghe, Mao Fu, Mark Walker, Ingrid B Borecki, George V Dedoussis, Andreas Fritsche, Claes Ohlsson, Michael Boehnke, Stefania Bandinelli, Cornelia M van Duijn, Shah Ebrahim, Debbie A Lawlor, Vilmundur Gudnason, Tamara B Harris, Thorkild I A Sørensen, Karen L Mohlke, Albert Hofman, André G Uitterlinden, Jaakko Tuomilehto, Terho Lehtimäki, Olli Raitakari, Bo Isomaa, Pål R Njølstad, Jose C Florez, Simin Liu, Andy Ness, Timothy D Spector, E Shyong Tai, Philippe Froguel, Heiner Boeing, Markku Laakso, Michael Marmot, Sven Bergmann, Chris Power, Kay-Tee Khaw, Daniel Chasman, Paul Ridker, Torben Hansen, Keri L Monda, Thomas Illig, Marjo-Riitta Järvelin, Nicholas J Wareham, Frank B Hu, Leif C Groop, Marju Orho-Melander, Ulf Ekelund, Paul W Franks, Ruth J F Loos
Published 2011-11-01