Ligand modulated antagonism of PPARgamma by genomic and non-genomic actions of PPARdelta.

by Mattias C U Gustafsson, Deborah Knight, Colin N A Palmer
Published 2009-09-01

Activation of PPARbeta/delta causes a psoriasis-like skin disease in vivo.

by Malgorzata Romanowska, Louise Reilly, Colin N A Palmer, Mattias C U Gustafsson, John Foerster
Published 2010-03-01

PPARα Is Required for PPARδ Action in Regulation of Body Weight and Hepatic Steatosis in Mice

by Wojciech G. Garbacz, Jeffrey T. J. Huang, Larry G. Higgins, Walter Wahli, Colin N. A. Palmer
Published 2015-01-01

Genetic and pharmacological relationship between P-glycoprotein and increased cardiovascular risk associated with clarithromycin prescription: An epidemiological and genomic popula...

by Ify R Mordi, Benjamin K Chan, N David Yanez, Colin N A Palmer, Chim C Lang, James D Chalmers
Published 2020-11-01

A Genome-wide Association Study Provides Evidence of Sex-specific Involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) With Diabetic Neuropathic Pain

by Weihua Meng, Harshal A. Deshmukh, Louise A. Donnelly, Nicola Torrance, Helen M. Colhoun, Colin N.A. Palmer, Blair H. Smith
Published 2015-10-01

Conditional Expression of Human PPARδ and a Dominant Negative Variant of hPPARδ In Vivo

by Larry G. Higgins, Wojciech G. Garbacz, Mattias C. U. Gustafsson, Sitheswaran Nainamalai, Peter R. Ashby, C. Roland Wolf, Colin N. A. Palmer
Published 2012-01-01

The impact of phenotype, ethnicity and genotype on progression of type 2 diabetes mellitus

by Anand Thakarakkattil Narayanan Nair, Louise A. Donnelly, Adem Y. Dawed, Sushrima Gan, Ranjit M. Anjana, Mohan Viswanathan, Colin N. A. Palmer, Ewan R. Pearson
Published 2020-04-01

Polymorphism in INSR Locus Modifies Risk of Atrial Fibrillation in Patients on Thyroid Hormone Replacement Therapy

by Enrique Soto-Pedre, Moneeza K. Siddiqui, Cyrielle Maroteau, Adem Y. Dawed, Alex S. Doney, Colin N. A. Palmer, Ewan R. Pearson, Graham P. Leese, Graham P. Leese
Published 2021-06-01

Carrier status for the common R501X and 2282del4 filaggrin mutations is not associated with hearing phenotypes in 5,377 children from the ALSPAC cohort.

by Santiago Rodriguez, Amanda J Hall, Raquel Granell, W H Irwin McLean, Alan D Irvine, Colin N A Palmer, George Davey Smith, John Henderson, Ian N M Day
Published 2009-06-01

Genetic Variation in Kruppel like Factor 15 Is Associated with Left Ventricular Hypertrophy in Patients with Type 2 Diabetes: Discovery and Replication Cohorts

by Sheila K. Patel, Bryan Wai, Chim C. Lang, Daniel Levin, Colin N.A. Palmer, Helen M. Parry, Elena Velkoska, Stephen B. Harrap, Piyush M. Srivastava, Louise M. Burrell
Published 2017-04-01

Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposure.

by Hans Bisgaard, Angela Simpson, Colin N A Palmer, Klaus Bønnelykke, Irwin McLean, Somnath Mukhopadhyay, Christian B Pipper, Liselotte B Halkjaer, Brian Lipworth, Jenny Hankinson, Ashley Woodcock, Adnan Custovic
Published 2008-06-01

Common Statin Intolerance Variants in ABCB1 and LILRB5 Show Synergistic Effects on Statin Response: An Observational Study Using Electronic Health Records

by Alaa’ Lutfi Melhem, Mehul Kumar Chourasia, Margherita Bigossi, Margherita Bigossi, Cyrielle Maroteau, Alasdair Taylor, Roberto Pola, Adem Y. Dawed, Aleksi Tornio, Aleksi Tornio, Colin N. A. Palmer, Moneeza K. Siddiqui
Published 2021-10-01

Application of pharmacogenomics and bioinformatics to exemplify the utility of human ex vivo organoculture models in the field of precision medicine.

by Karen Cowan, Graeme Macluskie, Michael Finch, Colin N A Palmer, Jane Hair, Max Bylesjo, Sarah Lynagh, Pamela Brankin, Marian McNeil, Carolyn Low, David Mallinson, Elaine M Gourlay, Hannah Child, Linda Cheyne, David C Bunton
Published 2019-01-01

Cohort profile: DOLORisk Dundee: a longitudinal study of chronic neuropathic pain

by Claire Jones, Blair H. Smith, Geert Crombez, Harry L. Hébert, Abirami Veluchamy, Georgios Baskozos, Francesca Fardo, Dimitri M. L. Van Ryckeghem, Mathilde M. V. Pascal, Keith Milburn, Ewan R. Pearson, David L. H. Bennett, Weihua Meng, Colin N. A. Palmer
Published 2021-06-01

Persistent C-peptide secretion in Type 1 diabetes and its relationship to the genetic architecture of diabetes

by Paul M. McKeigue, Athina Spiliopoulou, Stuart McGurnaghan, Marco Colombo, Luke Blackbourn, Timothy J. McDonald, Suna Onengut-Gomuscu, Stephen S. Rich, Colin N. A. Palmer, John A. McKnight, Mark W. J. Strachan, Alan W. Patrick, John Chalmers, Robert S. Lindsay, John R. Petrie, Sandeep Thekkepat, Andrew Collier, Sandra MacRury, Helen M. Colhoun
Published 2019-08-01

Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant.

by Colin N A Palmer, Cristina Maglio, Carlo Pirazzi, Maria Antonella Burza, Martin Adiels, Lindsay Burch, Louise A Donnelly, Helen Colhoun, Alexander S Doney, John F Dillon, Ewan R Pearson, Mark McCarthy, Andrew T Hattersley, Tim Frayling, Andrew D Morris, Markku Peltonen, Per-Arne Svensson, Peter Jacobson, Jan Borén, Lars Sjöström, Lena M S Carlsson, Stefano Romeo
Published 2012-01-01

DOLORisk: study protocol for a multi-centre observational study to understand the risk factors and determinants of neuropathic pain [version 2; referees: 2 approved]

by Mathilde M.V. Pascal, Andreas C. Themistocleous, Ralf Baron, Andreas Binder, Didier Bouhassira, Geert Crombez, Nanna B. Finnerup, Janne Gierthmühlen, Yelena Granovsky, Leif Groop, Harry L. Hebert, Troels S. Jensen, Kristinn Johnsen, Mark I. McCarthy, Weihua Meng, Colin N.A. Palmer, Andrew S.C. Rice, Jordi Serra, Romà Solà, David Yarnitsky, Blair H. Smith, Nadine Attal, David L.H. Bennett
Published 2019-02-01

Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and de...

by Ulla Sovio, Dennis O Mook-Kanamori, Nicole M Warrington, Robert Lawrence, Laurent Briollais, Colin N A Palmer, Joanne Cecil, Johanna K Sandling, Ann-Christine Syvänen, Marika Kaakinen, Lawrie J Beilin, Iona Y Millwood, Amanda J Bennett, Jaana Laitinen, Anneli Pouta, John Molitor, George Davey Smith, Yoav Ben-Shlomo, Vincent W V Jaddoe, Lyle J Palmer, Craig E Pennell, Tim J Cole, Mark I McCarthy, Marjo-Riitta Järvelin, Nicholas J Timpson, Early Growth Genetics Consortium
Published 2011-02-01

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference

by Laura J. Corbin, Vanessa Y. Tan, David A. Hughes, Kaitlin H. Wade, Dirk S. Paul, Katherine E. Tansey, Frances Butcher, Frank Dudbridge, Joanna M. Howson, Momodou W. Jallow, Catherine John, Nathalie Kingston, Cecilia M. Lindgren, Michael O’Donavan, Stephen O’Rahilly, Michael J. Owen, Colin N. A. Palmer, Ewan R. Pearson, Robert A. Scott, David A. van Heel, John Whittaker, Tim Frayling, Martin D. Tobin, Louise V. Wain, George Davey Smith, David M. Evans, Fredrik Karpe, Mark I. McCarthy, John Danesh, Paul W. Franks, Nicholas J. Timpson
Published 2018-02-01

Genetic loci for retinal arteriolar microcirculation.

by Xueling Sim, Richard A Jensen, M Kamran Ikram, Mary Frances Cotch, Xiaohui Li, Stuart MacGregor, Jing Xie, Albert Vernon Smith, Eric Boerwinkle, Paul Mitchell, Ronald Klein, Barbara E K Klein, Nicole L Glazer, Thomas Lumley, Barbara McKnight, Bruce M Psaty, Paulus T V M de Jong, Albert Hofman, Fernando Rivadeneira, Andre G Uitterlinden, Cornelia M van Duijn, Thor Aspelund, Gudny Eiriksdottir, Tamara B Harris, Fridbert Jonasson, Lenore J Launer, Wellcome Trust Case Control Consortium 2, John Attia, Paul N Baird, Stephen Harrap, Elizabeth G Holliday, Michael Inouye, Elena Rochtchina, Rodney J Scott, Ananth Viswanathan, Global BPGen Consortium, Guo Li, Nicholas L Smith, Kerri L Wiggins, Jane Z Kuo, Kent D Taylor, Alex W Hewitt, Nicholas G Martin, Grant W Montgomery, Cong Sun, Terri L Young, David A Mackey, Natalie R van Zuydam, Alex S F Doney, Colin N A Palmer, Andrew D Morris, Jerome I Rotter, E Shyong Tai, Vilmundur Gudnason, Johannes R Vingerling, David S Siscovick, Jie Jin Wang, Tien Y Wong
Published 2013-01-01