Both fasting and glucose-stimulated proinsulin levels predict hyperglycemia and incident type 2 diabetes: a population-based study of 9,396 Finnish men.

by Jagadish Vangipurapu, Alena Stančáková, Teemu Kuulasmaa, Johanna Kuusisto, Markku Laakso
Published 2015-01-01

Finnish Diabetes Risk Score Is Associated with Impaired Insulin Secretion and Insulin Sensitivity, Drug-Treated Hypertension and Cardiovascular Disease: A Follow-Up Study of the ME...

by Maria Fizelova, Raimo Jauhiainen, Alena Stančáková, Johanna Kuusisto, Markku Laakso
Published 2016-01-01

Rotation and torsion of the left ventricle with cardiovascular magnetic resonance tagging: comparison of two analysis methods

by Lauri Lehmonen, Mikko Jalanko, Mika Tarkiainen, Touko Kaasalainen, Johanna Kuusisto, Kirsi Lauerma, Sauli Savolainen
Published 2020-07-01

Simvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells.

by Nagendra Yaluri, Shalem Modi, Maykel López Rodríguez, Alena Stančáková, Johanna Kuusisto, Tarja Kokkola, Markku Laakso
Published 2015-01-01

Markers of tissue-specific insulin resistance predict the worsening of hyperglycemia, incident type 2 diabetes and cardiovascular disease.

by Mária Fízel'ová, Henna Cederberg, Alena Stančáková, Raimo Jauhiainen, Jagadish Vangipurapu, Johanna Kuusisto, Markku Laakso
Published 2014-01-01

Insulin sensitivity regulates cholesterol metabolism to a greater extent than obesity: lessons from the METSIM Study1

by Helena Gylling, Maarit Hallikainen, Jussi Pihlajamäki, Piia Simonen, Johanna Kuusisto, Markku Laakso, Tatu A. Miettinen
Published 2010-08-01

Novel biomarkers associated with incident heart failure in 10 106 Finnish men

by Raimo Jauhiainen, Matti Jauhiainen, Jagadish Vangipurapu, Teemu Kuulasmaa, Mika Ala‐Korpela, Markku Laakso, Johanna Kuusisto
Published 2021-02-01

Increased visceral adipose tissue as a potential risk factor in patients with embolic stroke of undetermined source (ESUS).

by Antti T Muuronen, Mikko Taina, Marja Hedman, Jarkko Marttila, Johanna Kuusisto, Juha Onatsu, Ritva Vanninen, Pekka Jäkälä, Petri Sipola, Pirjo Mustonen
Published 2015-01-01

Generation of a human induced pluripotent stem cell line from a patient with a rare A673T variant in amyloid precursor protein gene that reduces the risk for Alzheimer's disease

by Šárka Lehtonen, Ida Höytyläinen, Jenni Voutilainen, Tuuli-Maria Sonninen, Johanna Kuusisto, Markku Laakso, Riikka H. Hämäläinen, Minna Oksanen, Jari Koistinaho
Published 2018-07-01

The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases

by Markku Laakso, Johanna Kuusisto, Alena Stančáková, Teemu Kuulasmaa, Päivi Pajukanta, Aldons J. Lusis, Francis S. Collins, Karen L. Mohlke, Michael Boehnke
Published 2017-03-01

The Metabolome in Finnish Carriers of the MYBPC3-Q1061X Mutation for Hypertrophic Cardiomyopathy.

by Benedicte Jørgenrud, Mikko Jalanko, Tiina Heliö, Pertti Jääskeläinen, Mika Laine, Mika Hilvo, Markku S Nieminen, Markku Laakso, Tuulia Hyötyläinen, Matej Orešič, Johanna Kuusisto
Published 2015-01-01

Machine Learning Reveals Time-Varying Microbial Predictors with Complex Effects on Glucose Regulation

by Oliver Aasmets, Kreete Lüll, Jennifer M. Lang, Calvin Pan, Johanna Kuusisto, Krista Fischer, Markku Laakso, Aldons J. Lusis, Elin Org
Published 2021-02-01

Generation of a human induced pluripotent stem cell line (UEFi003-A) carrying heterozygous A673T variant in amyloid precursor protein associated with a reduced risk of Alzheimer’s...

by Taisia Rolova, Ying-Chieh Wu, Marja Koskuvi, Jenni Voutilainen, Tuuli-Maria Sonninen, Johanna Kuusisto, Markku Laakso, Riikka H. Hämäläinen, Jari Koistinaho, Šárka Lehtonen
Published 2020-10-01

Non-cholesterol sterol levels predict hyperglycemia and conversion to type 2 diabetes in Finnish men.

by Henna Cederberg, Helena Gylling, Tatu A Miettinen, Jussi Paananen, Jagadish Vangipurapu, Jussi Pihlajamäki, Teemu Kuulasmaa, Alena Stančáková, Ulf Smith, Johanna Kuusisto, Markku Laakso
Published 2013-01-01

The D299G/T399I Toll-like receptor 4 variant associates with body and liver fat: results from the TULIP and METSIM Studies.

by Peter Weyrich, Harald Staiger, Alena Stančáková, Fausto Machicao, Jürgen Machann, Fritz Schick, Norbert Stefan, Johanna Kuusisto, Markku Laakso, Silke Schäfer, Andreas Fritsche, Hans-Ulrich Häring
Published 2010-01-01

Structural Immaturity of Human iPSC-Derived Cardiomyocytes: In Silico Investigation of Effects on Function and Disease Modeling

by Jussi T. Koivumäki, Nikolay Naumenko, Tomi Tuomainen, Jouni Takalo, Jouni Takalo, Minna Oksanen, Katja A. Puttonen, Šárka Lehtonen, Johanna Kuusisto, Markku Laakso, Jari Koistinaho, Pasi Tavi
Published 2018-02-01

Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort

by Elin Org, Yuna Blum, Silva Kasela, Margarete Mehrabian, Johanna Kuusisto, Antti J. Kangas, Pasi Soininen, Zeneng Wang, Mika Ala-Korpela, Stanley L. Hazen, Markku Laakso, Aldons J. Lusis
Published 2017-04-01

Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.

by Hana Koutnikova, Markku Laakso, Lu Lu, Roy Combe, Jussi Paananen, Teemu Kuulasmaa, Johanna Kuusisto, Hans-Ulrich Häring, Torben Hansen, Oluf Pedersen, Ulf Smith, Markolf Hanefeld, Robert W Williams, Johan Auwerx
Published 2009-08-01

Serum lipidomics meets cardiac magnetic resonance imaging: profiling of subjects at risk of dilated cardiomyopathy.

by Marko Sysi-Aho, Juha Koikkalainen, Tuulikki Seppänen-Laakso, Maija Kaartinen, Johanna Kuusisto, Keijo Peuhkurinen, Satu Kärkkäinen, Margareta Antila, Kirsi Lauerma, Eeva Reissell, Raija Jurkko, Jyrki Lötjönen, Tiina Heliö, Matej Orešič
Published 2011-01-01

The birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associates with elevated insulin release following an oral glucose challenge.

by Ehm A Andersson, Marie N Harder, Kasper Pilgaard, Charlotta Pisinger, Alena Stančáková, Johanna Kuusisto, Niels Grarup, Kristine Færch, Pernille Poulsen, Daniel R Witte, Torben Jørgensen, Allan Vaag, Markku Laakso, Oluf Pedersen, Torben Hansen
Published 2011-01-01