Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates

by Wyant, Gregory A, Abu-Remaileh, Monther, Sabatini, David M.
Published 2020

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

by Freinkman, Elizaveta, Wang, Tim, Chen, Walter W., Abu-Remaileh, Monther, Sabatini, David, Birsoy, Kivanc
Published 2017

Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase

by Cantor, Jason R., Abu-Remaileh, Monther, Kanarek, Naama, Freinkman, Elizaveta, Gao, Xin, Louissaint, Abner, Lewis, Caroline A., Sabatini, David
Published 2018

Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes

by Chan, Sze Ham, Freinkman, Elizaveta, Abu-Remaileh, Monther, Wyant, Gregory Andrew, Kim, Choah, Laqtom, Nouf N, Abbasi, Maria, Sabatini, David
Published 2019

mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient

by Freinkman, Elizaveta, Wyant, Gregory Andrew, Abu-Remaileh, Monther, Wolfson, Rachel Laura, Chen, Walter W., Danai, Laura V, Vander Heiden, Matthew G., Sabatini, David
Published 2018

NUFIP1 is a ribosome receptor for starvation-induced ribophagy

by Wyant, Gregory A., Abu-Remaileh, Monther, Frenkel, Evgeni M., Laqtom, Nouf N., Dharamdasani, Vimisha, Lewis, Caroline A., Chan, Sze Ham, Sabatini, David M.
Published 2020

Histidine catabolism is a major determinant of methotrexate sensitivity

by Kanarek, Naama, Keys, Heather R., Cantor, Jason R., Lewis, Caroline A., Chan, Sze Ham, Kunchok, Tenzin, Abu-Remaileh, Monther, Freinkman, Elizaveta, Sabatini, David M.
Published 2020

MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo

by Bayraktar, Erol C., Baudrier, Lou, Özerdem, Ceren, Lewis, Caroline A., Chan, Sze Ham, Kunchok, Tenzin, Abu-Remaileh, Monther, Cangelosi, Andrew L., Sabatini, David M., Birsoy, Kıvanç, Chen, Walter W.
Published 2020

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1

by Shen, Kuang, Petri, Sabrina, Abu-Remaileh, Monther, Frankel, Wayne N., Wolfson, Rachel Laura, Chantranupong, Lynne, Wyant, Gregory Andrew, Gu, Xin, Orozco Segrera, Jose, Condon, Kendall Janine, Kedir, Jibril Fetu, Scaria, Sonia M., Sabatini, David
Published 2018

Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging

by Mihaylova, Maria M., Cheng, Chia-Wei, Cao, Amanda Q., Tripathi, Surya, Mana, Miyeko D., Bauer-Rowe, Khristian E., Abu-Remaileh, Monther, Clavain, Laura, Erdemir, Aysegul, Lewis, Caroline A., Freinkman, Elizaveta, Huang, Yanmei, Bell, George W., Sabatini, David M., Yilmaz, Ömer H.
Published 2020

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

by Chan, Sze Ham, Lewis, Caroline, Swier, Lotteke J. Y. M., Chen, Walter W., Sullivan, Lucas Bryan, Fiske, Brian Prescott, Cho, Sung Won, Abu-Remaileh, Monther, Liu, Chieh Ming Jamin, Zhou, Minerva H., Koh, Min Jung, Chung, Haeyoon, Davidson, Shawn M, Luengo, Alba, Vander Heiden, Matthew G., Sabatini, David, Pacold, Michael Edward
Published 2017

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

by Saadatpour, Assieh, Hong, Sue-Jean, Pinello, Luca, Katz, Yarden, Lamming, Dudley W., Guo, Guoji, Bell, George W., Selig, Martin, Nielsen, G. Petur, Gupta, Nitin, Ferrone, Cristina R., Deshpande, Vikram, Yuan, Guo-Cheng, Orkin, Stuart H., Beyaz, Semir, Mana, Miyeko, Roper, Jatin, Kedrin, Dmitriy, Bauer-Rowe, Khristian E., Xifaras, Michael, Akkad, Adam, Arias, Erika, Shinagare, Shweta, Abu-Remaileh, Monther, Dogum, Rizkullah, Sabatini, David, Yilmaz, Omer, Mihaylova, Maria M.
Published 2017