Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs

by Sabatini, David M.
Published 2020

DEPTOR modulates activation responses in CD4+ T cells and enhances immunoregulation following transplantation

by Sabatini, David M.
Published 2020

C7orf59/LAMTOR4 phosphorylation and structural flexibility modulate Ragulator assembly

by Shen, Kuang, Sabatini, David M.
Published 2020

Nutrient mTORC1 signaling underpins regulatory T cell control of immune tolerance

by Efeyan, Alejo, Sabatini, David M.
Published 2020

Myeloid-Specific Rictor Deletion Induces M1 Macrophage Polarization and Potentiates In Vivo Pro-Inflammatory Response to Lipopolysaccharide

by Festuccia, William T., Pouliot, Philippe, Bakan, Inan, Sabatini, David M., Laplante, Mathieu, Sabatini, David M.
Published 2014

A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility

by Wolfson, Rachel L., Sabatini, David M.
Published 2020

Nutrients versus growth factors in mTORC1 activation

by Efeyan, Alejo, Sabatini, David M, Sabatini, David
Published 2015

mTOR Signaling in Growth Control and Disease

by Laplante, Mathieu, Sabatini, David M, Sabatini, David
Published 2014

Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program

by Kang, Seong Anthony Woo, Sabatini, David M.
Published 2020

A Radical Role for TOR in Longevity

by Lamming, Dudley W, Sabatini, David M, Sabatini, David
Published 2014

Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates

by Wyant, Gregory A, Abu-Remaileh, Monther, Sabatini, David M.
Published 2020

Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death

by Freinkman, Elizaveta, Chan, Sze Ham, Lewis, Caroline, Sabatini, David M.
Published 2020

A Central Role for mTOR in Lipid Homeostasis

by Lamming, Dudley W, Sabatini, David M, Lamming, Dudley W., Sabatini, David
Published 2016

Defective Regulation of Autophagy upon Leucine Deprivation Reveals a Targetable Liability of Human Melanoma Cells In Vitro and In Vivo

by Sheen, Joon-Ho, Zoncu, Roberto, Kim, Dohoon, Sabatini, David M, Sabatini, David
Published 2014

Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1

by Bar-Peled, Liron, Zoncu, Roberto, Sabatini, David M, Schweitzer, Lawrence David, Sabatini, David
Published 2014

Dietary and Metabolic Control of Stem Cell Function in Physiology and Cancer

by Mihaylova, Maria M, Sabatini, David M, Yilmaz, Omer, Mihaylova, Maria M., Sabatini, David
Published 2016

Glyceraldehyde 3-phosphate dehydrogenase modulates nonoxidative pentose phosphate pathway to provide anabolic precursors in hypoxic tumor cells

by Ahn, Woo S., Dong, Wentao, Zhang, Zhe, Cantor, Jason R., Sabatini, David M., Iliopoulos, Othon, Stephanopoulos, Gregory
Published 2022

DEPTOR Cell-Autonomously Promotes Adipogenesis, and Its Expression Is Associated with Obesity

by Laplante, Mathieu, Horvat, Simon, Festuccia, William T., Birsoy, Kivanc, Prevorsek, Zala, Efeyan, Alejo, Sabatini, David M, Sabatini, David
Published 2014

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

by Zoncu, Roberto, Bar-Peled, Liron, Efeyan, Alejo, Sancak, Yasemin, Sabatini, David M., Wang, Shuyu, Ph. D. Massachusetts Institute of Technology
Published 2015