Both Pharmacokinetic Variability and Granuloma Heterogeneity Impact the Ability of the First-Line Antibiotics to Sterilize Tuberculosis Granulomas

by Joseph M. Cicchese, Véronique Dartois, Véronique Dartois, Denise E. Kirschner, Jennifer J. Linderman
Published 2020-03-01

Editorial: NTM—The New Uber-Bugs

by Veronique Dartois, Christine Sizemore, Thomas Dick
Published 2019-06-01

Polyamines inhibit porin-mediated fluoroquinolone uptake in mycobacteria.

by Jansy Passiflora Sarathy, Edmund Lee, Véronique Dartois
Published 2013-01-01

Indole Propionic Acid, an Unusual Antibiotic Produced by the Gut Microbiota, With Anti-inflammatory and Antioxidant Properties

by Dereje Abate Negatu, Dereje Abate Negatu, Martin Gengenbacher, Martin Gengenbacher, Véronique Dartois, Véronique Dartois, Thomas Dick, Thomas Dick, Thomas Dick
Published 2020-10-01

The Role of Transport Mechanisms in Mycobacterium Tuberculosis Drug Resistance and Tolerance

by Jansy Passiflora Sarathy, Véronique Dartois, Edmund Jon Deoon Lee
Published 2012-11-01

Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach.

by Elsje Pienaar, Jansy Sarathy, Brendan Prideaux, Jillian Dietzold, Véronique Dartois, Denise E Kirschner, Jennifer J Linderman
Published 2017-08-01

Teicoplanin – Tigecycline Combination Shows Synergy Against Mycobacterium abscessus

by Dinah B. Aziz, Dinah B. Aziz, Jeanette W. P. Teo, Véronique Dartois, Thomas Dick, Thomas Dick
Published 2018-05-01

BCG induces protection against Mycobacterium tuberculosis infection in the Wistar rat model.

by Amit Singhal, Vanessa Mathys, Mehdi Kiass, Colette Creusy, Baptiste Delaire, El Moukhtar Aliouat, Véronique Dartois, Gilla Kaplan, Pablo Bifani
Published 2011-01-01

Adjunctive Phosphodiesterase-4 Inhibitor Therapy Improves Antibiotic Response to Pulmonary Tuberculosis in a Rabbit Model

by Selvakumar Subbian, Liana Tsenova, Jennifer Holloway, Blas Peixoto, Paul O'Brien, Véronique Dartois, Vikram Khetani, Jerome B. Zeldis, Gilla Kaplan
Published 2016-02-01

Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in Mycobacterium tuberculosis

by Dereje Abate Negatu, Yoshiyuki Yamada, Yu Xi, Mei Lin Go, Matthew Zimmerman, Uday Ganapathy, Véronique Dartois, Martin Gengenbacher, Thomas Dick
Published 2019-03-01

Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs.

by Selvakumar Subbian, Liana Tsenova, Paul O'Brien, Guibin Yang, Mi-Sun Koo, Blas Peixoto, Dorothy Fallows, Veronique Dartois, George Muller, Gilla Kaplan
Published 2011-09-01

High-resolution mapping of fluoroquinolones in TB rabbit lesions reveals specific distribution in immune cell types

by Landry Blanc, Isaac B Daudelin, Brendan K Podell, Pei-Yu Chen, Matthew Zimmerman, Amanda J Martinot, Rada M Savic, Brendan Prideaux, Véronique Dartois
Published 2018-11-01

Inhibition of Fatty Acid Oxidation Promotes Macrophage Control of Mycobacterium tuberculosis

by Pallavi Chandra, Li He, Matthew Zimmerman, Guozhe Yang, Stefan Köster, Mireille Ouimet, Han Wang, Kathyrn J. Moore, Véronique Dartois, Joel D. Schilling, Jennifer A. Philips
Published 2020-07-01

Tuberculosis drugs' distribution and emergence of resistance in patient's lung lesions: A mechanistic model and tool for regimen and dose optimization.

by Natasha Strydom, Sneha V Gupta, William S Fox, Laura E Via, Hyeeun Bang, Myungsun Lee, Seokyong Eum, TaeSun Shim, Clifton E Barry, Matthew Zimmerman, Véronique Dartois, Radojka M Savic
Published 2019-04-01

Matrix metalloproteinase inhibitors enhance the efficacy of frontline drugs against Mycobacterium tuberculosis.

by Yitian Xu, Lihua Wang, Matthew D Zimmerman, Kai-Yuan Chen, Lu Huang, Dah-Jiun Fu, Firat Kaya, Nikolai Rakhilin, Evgeniya V Nazarova, Pengcheng Bu, Veronique Dartois, David G Russell, Xiling Shen
Published 2018-04-01

NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans

by Martin Gengenbacher, Maria A. Duque-Correa, Peggy Kaiser, Stefanie Schuerer, Doris Lazar, Ulrike Zedler, Stephen T. Reece, Amit Nayyar, Stewart T. Cole, Vadim Makarov, Clifton E. Barry III, Véronique Dartois, Stefan H. E. Kaufmann
Published 2017-08-01

Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific.

by Valentina Guerrini, Brendan Prideaux, Landry Blanc, Natalie Bruiners, Riccardo Arrigucci, Sukhwinder Singh, Hsin Pin Ho-Liang, Hugh Salamon, Pei-Yu Chen, Karim Lakehal, Selvakumar Subbian, Paul O'Brien, Laura E Via, Clifton E Barry, Véronique Dartois, Maria Laura Gennaro
Published 2018-08-01

Linezolid Trough Concentrations Correlate with Mitochondrial Toxicity-Related Adverse Events in the Treatment of Chronic Extensively Drug-Resistant Tuberculosis

by Taeksun Song, Myungsun Lee, Han-Seung Jeon, Yumi Park, Lori E. Dodd, Véronique Dartois, Dean Follman, Jing Wang, Ying Cai, Lisa C. Goldfeder, Kenneth N. Olivier, Yingda Xie, Laura E. Via, Sang Nae Cho, Clifton E. Barry III, Ray Y. Chen
Published 2015-11-01

Experimental tuberculosis in the Wistar rat: a model for protective immunity and control of infection.

by Amit Singhal, El Moukhtar Aliouat, Maxime Hervé, Vanessa Mathys, Mehdi Kiass, Colette Creusy, Baptiste Delaire, Liana Tsenova, Laurence Fleurisse, Julie Bertout, Luis Camacho, Damian Foo, Hui Chien Tay, Jie Yee Siew, Warda Boukhouchi, Marta Romano, Barun Mathema, Véronique Dartois, Gilla Kaplan, Pablo Bifani
Published 2011-01-01

Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB.

by Ruslana Bryk, Shashirekha Mundhra, Xiuju Jiang, Madeleine Wood, Daniel Pfau, Elaina Weber, Suna Park, Li Zhang, Colin Wilson, Renier Van der Westhuyzen, Leslie Street, Kelly Chibale, Matthew Zimmerman, Véronique Dartois, Nunzia Pastore, Andrea Ballabio, Natalie Hawryluk, Stacie Canan, Vikram Khetani, Joseph Camardo, Carl Nathan
Published 2020-06-01