Host targeted activity of pyrazinamide in Mycobacterium tuberculosis infection.

by Claudia Manca, Mi-Sun Koo, Blas Peixoto, Dorothy Fallows, Gilla Kaplan, Selvakumar Subbian
Published 2013-01-01

A combination of baseline plasma immune markers can predict therapeutic response in multidrug resistant tuberculosis.

by Selena Ferrian, Claudia Manca, Sugnet Lubbe, Francesca Conradie, Nazir Ismail, Gilla Kaplan, Clive M Gray, Dorothy Fallows
Published 2017-01-01

Chronic pulmonary cavitary tuberculosis in rabbits: a failed host immune response

by Selvakumar Subbian, Liana Tsenova, Guibin Yang, Paul O'Brien, Sven Parsons, Blas Peixoto, Leslie Taylor, Dorothy Fallows, Gilla Kaplan
Published 2011-01-01

Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs.

by Selvakumar Subbian, Liana Tsenova, Paul O'Brien, Guibin Yang, Mi-Sun Koo, Blas Peixoto, Dorothy Fallows, Veronique Dartois, George Muller, Gilla Kaplan
Published 2011-09-01

Effect of standard tuberculosis treatment on plasma cytokine levels in patients with active pulmonary tuberculosis.

by Catherine Riou, Blas Perez Peixoto, Lindi Roberts, Katharina Ronacher, Gerhard Walzl, Claudia Manca, Roxana Rustomjee, Thuli Mthiyane, Dorothy Fallows, Clive M Gray, Gilla Kaplan
Published 2012-01-01

Phosphodiesterase 4 inhibition reduces innate immunity and improves isoniazid clearance of Mycobacterium tuberculosis in the lungs of infected mice.

by Mi-Sun Koo, Claudia Manca, Guibin Yang, Paul O'Brien, Nackmoon Sung, Liana Tsenova, Selvakumar Subbian, Dorothy Fallows, George Muller, Sabine Ehrt, Gilla Kaplan
Published 2011-02-01

Frequency of Circulating CD4+Ki67+HLA-DR− T Regulatory Cells Prior to Treatment for Multidrug Resistant Tuberculosis Can Differentiate the Severity of Disease and Predict Time to C...

by Selena Ferrian, Melinda Ross, Francesca Conradie, Shaheed Vally Omar, Nazir Ismail, Nazir Ismail, Francesca Little, Gilla Kaplan, Dorothy Fallows, Clive M. Gray, Clive M. Gray
Published 2018-10-01

Correlation of rpoB mutations with minimal inhibitory concentration of Rifampin and Rifabutin in Mycobacterium tuberculosis in an HIV/AIDS endemic setting, South Africa

by Ivy - Rukasha, Halima Mohammed Said, Halima Mohammed Said, Shaheed Vally Omar, Hendrik - Koornhoof, Andries W Dreyer, Alfred - Musekiwa, Harry Moultrie, Anwar A Hoosen, Gilla Kaplan, Dorothy Fallows, Nazir Ismail
Published 2016-12-01

A Novel Molecular Strategy for Surveillance of Multidrug Resistant Tuberculosis in High Burden Settings.

by Halima M Said, Nicole Kushner, Shaheed V Omar, Andries W Dreyer, Hendrik Koornhof, Linda Erasmus, Yasmin Gardee, Ivy Rukasha, Elena Shashkina, Natalie Beylis, Gilla Kaplan, Dorothy Fallows, Nazir A Ismail
Published 2016-01-01

A subset of circulating blood mycobacteria-specific CD4 T cells can predict the time to Mycobacterium tuberculosis sputum culture conversion.

by Catherine Riou, Clive M Gray, Masixole Lugongolo, Thabisile Gwala, Agano Kiravu, Pamela Deniso, Lynsey Stewart-Isherwood, Shaheed Vally Omar, Martin P Grobusch, Gerrit Coetzee, Francesca Conradie, Nazir Ismail, Gilla Kaplan, Dorothy Fallows
Published 2014-01-01