Synchronous disease kinetics in a murine model for enterohemorrhagic E. coli infection using food-borne inoculation

by Laurice J Flowers, Elsa N Bou Ghanem, John M Leong
Published 2016-11-01

Prophage induction, but not production of phage particles, is required for lethal disease in a microbiome-replete murine model of enterohemorrhagic E. coli infection.

by Sowmya Balasubramanian, Marcia S Osburne, Haley BrinJones, Albert K Tai, John M Leong
Published 2019-01-01

Pearls collections: What we can learn about infectious disease and cancer.

by Laura J Knoll, Deborah A Hogan, John M Leong, Joseph Heitman, Richard C Condit
Published 2018-03-01

Strain-specific variation of the decorin-binding adhesin DbpA influences the tissue tropism of the lyme disease spirochete.

by Yi-Pin Lin, Vivian Benoit, Xiuli Yang, Raúl Martínez-Herranz, Utpal Pal, John M Leong
Published 2014-07-01

Bacterial and host determinants of MAL activation upon EPEC infection: the roles of Tir, ABRA, and FLRT3.

by Robert J W Heath, John M Leong, Balázs Visegrády, Laura M Machesky, Ramnik J Xavier
Published 2011-04-01

Strain-specific joint invasion and colonization by Lyme disease spirochetes is promoted by outer surface protein C.

by Yi-Pin Lin, Xi Tan, Jennifer A Caine, Mildred Castellanos, George Chaconas, Jenifer Coburn, John M Leong
Published 2020-05-01

A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response

by Dakshina M. Jandhyala, John Wong, Nicholas J. Mantis, Bruce E. Magun, John M. Leong, Cheleste M. Thorpe
Published 2016-09-01

The Alpha-Tocopherol Form of Vitamin E Boosts Elastase Activity of Human PMNs and Their Ability to Kill Streptococcus pneumoniae

by Elsa N. Bou Ghanem, James N. Lee, Basma H. Joma, Simin N. Meydani, John M. Leong, Alexander Panda
Published 2017-05-01

Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection

by Andrew Zukauskas, Randall J. Mrsny, Paula Cortés Barrantes, Jerrold R. Turner, John M. Leong, Beth A. McCormick
Published 2018-07-01

Calpain mediates epithelial cell microvillar effacement by enterohemorrhagic Escherichia coli

by YuShuan eLai, Kathleen eRiley, Andrew eCai, Andrew eCai, John M Leong, Ira M. Herman
Published 2011-11-01

Allele- and Tir-independent functions of intimin in diverse animal infection models

by Emily M Mallick, Michael John Brady, Steven A Luperchio, Vijay eVanguri, Loranne eMagoun, Hui eLiu, Barbara J Sheppard, Jean eMukherjee, Arthur eDonohue-Rolfe, Saul eTzipori, John M Leong, John M Leong, David B Schauer, David B Schauer
Published 2012-01-01

Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation

by Giang T. Nguyen, Shuying Xu, Walter Adams, John M. Leong, Stephen C. Bunnell, Michael K. Mansour, David B. Sykes, Joan Mecsas
Published 2021-08-01

Attaching-and-Effacing Pathogens Exploit Junction Regulatory Activities of N-WASP and SNX9 to Disrupt the Intestinal Barrier

by John J. Garber, Emily M. Mallick, Karen M. Scanlon, Jerrold R. Turner, Michael S. Donnenberg, John M. Leong, Scott B. Snapper
Published 2018-01-01

Scalable Reporter Assays to Analyze the Regulation of <i>stx2</i> Expression in Shiga Toxin-Producing Enteropathogens

by Martin B. Koeppel, Jana Glaser, Tobias Baumgartner, Stefanie Spriewald, Roman G. Gerlach, Benedikt von Armansperg, John M. Leong, Bärbel Stecher
Published 2021-07-01

Extracellular Adenosine Protects against Streptococcus pneumoniae Lung Infection by Regulating Pulmonary Neutrophil Recruitment.

by Elsa N Bou Ghanem, Stacie Clark, Sara E Roggensack, Sally R McIver, Pilar Alcaide, Philip G Haydon, John M Leong
Published 2015-08-01

Safe and effective delivery of supplemental iron to healthy older adults: The double-blind, randomized, placebo-controlled trial protocol of the Safe Iron Study [version 2; peer re...

by Erin D. Lewis, Dayong Wu, Joel B. Mason, Athar H. Chishti, John M. Leong, Kathryn Barger, Simin N. Meydani, Gerald F. Combs
Published 2021-02-01

The EHEC type III effector NleL is an E3 ubiquitin ligase that modulates pedestal formation.

by Heather Piscatelli, Shalaka A Kotkar, Megan E McBee, Sureshkumar Muthupalani, David B Schauer, Robert E Mandrell, John M Leong, Daoguo Zhou
Published 2011-04-01

Enterohemorrhagic E. coli requires N-WASP for efficient type III translocation but not for EspFU-mediated actin pedestal formation.

by Didier Vingadassalom, Kenneth G Campellone, Michael J Brady, Brian Skehan, Scott E Battle, Douglas Robbins, Archana Kapoor, Gail Hecht, Scott B Snapper, John M Leong
Published 2010-08-01

Enhanced actin pedestal formation by enterohemorrhagic Escherichia coli O157:H7 adapted to the mammalian host.

by Michael John Brady, Padhma eRadhakrishnan, Hui eLiu, Loranne eMagoun, Kenan C Murphy, Jean eMukherjee, Arthur eDonohue-Rolfe, Saul eTzipori, John M Leong
Published 2011-11-01

Repetitive N-WASP-binding elements of the enterohemorrhagic Escherichia coli effector EspF(U) synergistically activate actin assembly.

by Kenneth G Campellone, Hui-Chun Cheng, Douglas Robbins, Anosha D Siripala, Emma J McGhie, Richard D Hayward, Matthew D Welch, Michael K Rosen, Vassilis Koronakis, John M Leong
Published 2008-10-01