mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin

by Cervantes, Christopher L., Lim, Daniel Cham-Chin, Kang, Seong A., Pacold, Michael E., Lou, Hua Jane, Ottina, Kathleen, Gray, Nathanael S., Turk, Benjamin E., Yaffe, Michael B, Sabatini, David
Published 2014

A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1

by Bar-Peled, Liron, Chantranupong, Lynne, Cherniack, Andrew D., Chen, Walter W., Ottina, Kathleen, Grabiner, Brian C., Spear, Eric D., Carter, Scott L., Meyerson, Matthew L., Sabatini, David M.
Published 2014

mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin

by Kang, Seong A., Cervantes, Christopher L., Lim, Daniel Cham-Chin, Ottina, Kathleen, Lou, Hua Jane, Gray, Nathanael S., Turk, Benjamin E., Pacold, Michael Edward, Yaffe, Michael B, Sabatini, David
Published 2014

The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

by Rameseder, J., Zhang, Y., Ottina, Kathleen, Lim, D., Choi, Y., Gray, Nathanael S., Yaffe, M. B., Marto, Jarrod A., Hsu, Peggy P., Kang, Seong A., Peterson, Timothy R., Sabatini, David M.
Published 2013

Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1-S6K pathway signaling

by Lindquist, Robert A., Ottina, Kathleen, Wheeler, Douglas B., Hsu, Peggy P., Thoreen, Carson C., Guertin, David A., Ali, Siraj M., Sengupta, Shomit, Shaul, Yoav D., Lamprecht, Michael R., Madden, Katherine L., Papallo, Adam R., Jones, Thouis R., Sabatini, David M., Carpenter, Anne E.
Published 2012

Systematic identification of signaling pathways with potential to confer anticancer drug resistance

by Martz, C. A., Ottina, Kathleen, Singleton, K. R., Jasper, J. S., Wardell, S. E., Peraza-Penton, A., Anderson, G. R., Winter, P. S., Alley, H. M., Kwong, L. N., Cooper, Z. A., Tetzlaff, M., Chen, P.-L, Rathmell, J. C., Flaherty, K. T., Wargo, J. A., McDonnell, D. P., Wood, K. C., Wang, Tim, Sabatini, David
Published 2015

Functional genomics reveals serine synthesis is essential in PHGDH-amplified breast cancer

by Possemato, Richard, Marks, Kevin M., Kim, Dohoon, Birsoy, Kivanc, Sethumadhavan, Shalini, Woo, Hin-Koon, Jang, Hyun G., Jha, Abhishek K., Chen, Walter W., Barrett, Francesca G., Stransky, Nicolas, Tsun, Zhi-Yang, Cowley, Glenn S., Barretina, Jordi, Kalaany, Nada Y., Hsu, Peggy P., Ottina, Kathleen, Chan, Albert M., Yuan, Bingbing B., Garraway, Levi A., Root, David E., Mino-Kenudson, Mari, Brachtel, Elena F., Driggers, Edward M., Shaul, Yoav, Pacold, Michael Edward, Sabatini, David
Published 2012