DNA Damage and Repair in Human Cancer: Molecular Mechanisms and Contribution to Therapy-Related Leukemias

by Margherita Bignami, Cecilia Bossa, Ida Casorelli
Published 2012-07-01

Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function.

by Ivana Murfuni, Giorgia Basile, Shyamal Subramanyam, Eva Malacaria, Margherita Bignami, Maria Spies, Annapaola Franchitto, Pietro Pichierri
Published 2013-10-01

hMTH1 expression protects mitochondria from Huntington's disease-like impairment

by Ilenia Ventura, Maria Teresa Russo, Chiara De Nuccio, Gabriele De Luca, Paolo Degan, Antonietta Bernardo, Sergio Visentin, Luisa Minghetti, Margherita Bignami
Published 2013-01-01

The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis.

by Ida Casorelli, Tania Pannellini, Gabriele De Luca, Paolo Degan, Federica Chiera, Ivano Iavarone, Alessandro Giuliani, Alessia Butera, Monica Boirivant, Piero Musiani, Margherita Bignami
Published 2010-01-01

A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration.

by Gabriele De Luca, Maria Teresa Russo, Paolo Degan, Cecilia Tiveron, Andrea Zijno, Ettore Meccia, Ilenia Ventura, Elisabetta Mattei, Yusaku Nakabeppu, Marco Crescenzi, Rita Pepponi, Antonella Pèzzola, Patrizia Popoli, Margherita Bignami
Published 2008-11-01

Oxidative Stress, Mutations and Chromosomal Aberrations Induced by In Vitro and In Vivo Exposure to Furan

by Maria Teresa Russo, Gabriele De Luca, Nieves Palma, Paola Leopardi, Paolo Degan, Serena Cinelli, Gaetano Pepe, Pasquale Mosesso, Emma Di Carlo, Carlo Sorrentino, Piero Musiani, Riccardo Crebelli, Margherita Bignami, Eugenia Dogliotti
Published 2021-09-01

Evaluation of calcium lignosulfonate as a acceptable previous cargo for edible fats and oils

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Heather Wallace, Konrad Grob, Laurence Castle, Anna Christodoulidou, Christiane Vleminckx
Published 2019-12-01

A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer

by Alessandra Viel, Alessandro Bruselles, Ettore Meccia, Mara Fornasarig, Michele Quaia, Vincenzo Canzonieri, Eleonora Policicchio, Emanuele Damiano Urso, Marco Agostini, Maurizio Genuardi, Emanuela Lucci-Cordisco, Tiziana Venesio, Aline Martayan, Maria Grazia Diodoro, Lupe Sanchez-Mete, Vittoria Stigliano, Filomena Mazzei, Francesca Grasso, Alessandro Giuliani, Marta Baiocchi, Roberta Maestro, Giuseppe Giannini, Marco Tartaglia, Ludmil B. Alexandrov, Margherita Bignami
Published 2017-06-01

Update of the risk assessment of nickel in food and drinking water

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Thierry Guérin, Peter Massanyi, Henk Van Loveren, Katleen Baert, Petra Gergelova, Elsa Nielsen
Published 2020-11-01

Presence of free gossypol in whole cottonseed

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Michael Dinovi, Lutz Edler, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Carlo Stefano Nebbia, Isabelle P Oswald, Annette Petersen, Martin Rose, Alain‐Claude Roudot, Tanja Schwerdtle, Christiane Vleminckx, Günter Vollmer, Heather Wallace, Jan Alexander, Bruce Cottrill, Karen Mackay
Published 2017-07-01

Update of the risk assessment of hexabromocyclododecanes (HBCDDs) in food

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Heather Wallace, Diane Benford, Peter Fürst, Martin Rose, Sofia Ioannidou, Marina Nikolič, Luisa Ramos Bordajandi, Christiane Vleminckx
Published 2021-03-01

Evaluation of the shucking of certain species of scallops contaminated with domoic acid with a view to the production of edible parts meeting the safety requirements foreseen in th...

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Kevin James Chipman, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Ana Gago Martinez, Arjen Gerssen, Aurelia Tubaro, Claudia Cascio, José Cortiñas Abrahantes, Hans Steinkellner, Laurentius (Ron) Hoogenboom
Published 2021-08-01

Risks for human health related to the presence of pyrrolizidine alkaloids in honey, tea, herbal infusions and food supplements

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Jan Alexander, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Bruce Cottrill, Michael Dinovi, Lutz Edler, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Carlo Stefano Nebbia, Isabelle P. Oswald, Annette Petersen, Martin Rose, Alain‐Claude Roudot, Tanja Schwerdtle, Christiane Vleminckx, Günter Vollmer, Heather Wallace, José Angel Gomez Ruiz, Marco Binaglia
Published 2017-07-01

Assessment of a decontamination process for dioxins and dioxin‐like PCBs in fish oil by physical filtration with activated carbon

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Jan Alexander, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Bruce Cottrill, Michael Dinovi, Lutz Edler, Bettina Grasl‐Kraupp, Laurentius (Ron) Hoogenboom, Carlo Stefano Nebbia, Isabelle P. Oswald, Annette Petersen, Martin Rose, Alain‐Claude Roudot, Tanja Schwerdtle, Christiane Vleminckx, Günter Vollmer, Heather Wallace, Anne‐Katrine Lundebye, Manfred Metzler, Paolo Colombo, Christer Hogstrand
Published 2017-07-01

Evaluation of the shucking of certain species of scallops contaminated with lipophilic toxins with a view to the production of edible parts meeting the safety requirements foreseen...

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Kevin James Chipman, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Ana Gago Martinez, Arjen Gerssen, Aurelia Tubaro, Claudia Cascio, José  Cortiñas  Abrahantes, Hans Steinkellner, Laurentius (Ron) Hoogenboom
Published 2021-03-01

Assessment of a decontamination process for hydrocyanic acid in linseed intended for use in animal feed

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Jan Alexander, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Bruce Cottrill, Michael Dinovi, Lutz Edler, Bettina Grasl‐Kraupp, Laurentius (Ron) Hoogenboom, Carlo Stefano Nebbia, Isabelle P. Oswald, Annette Petersen, Martin Rose, Alain‐Claude Roudot, Tanja Schwerdtle, Christiane Vleminckx, Günter Vollmer, Heather Wallace, Anne‐Katrine Lundebye, Manfred Metzler, Paolo Colombo, Christer Hogstrand
Published 2017-10-01

Evaluation of the health risks related to the presence of cyanogenic glycosides in foods other than raw apricot kernels

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Christiane Vleminckx, Heather Wallace, Diane Benford, Leon Brimer, Francesca Romana Mancini, Manfred Metzler, Barbara Viviani, Andrea Altieri, Davide Arcella, Hans Steinkellner, Tanja Schwerdtle
Published 2019-04-01

Risk assessment of ochratoxin A in food

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Jan Alexander, Chiara Dall'Asta, Angela Mally, Manfred Metzler, Marco Binaglia, Zsuzsanna Horváth, Hans Steinkellner, Margherita Bignami
Published 2020-05-01

Assessment of a decontamination process for dioxins and PCBs from fish meal by hexane extraction and replacement of fish oil

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Jan Alexander, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Bruce Cottrill, Michael Dinovi, Lutz Edler, Bettina Grasl‐Kraupp, Laurentius (Ron) Hoogenboom, Carlo Stefano Nebbia, Isabelle P Oswald, Annette Petersen, Martin Rose, Alain‐Claude Roudot, Tanja Schwerdtle, Christiane Vleminckx, Günter Vollmer, Heather Wallace, Anne‐Katrine Lundebye, Manfred Metzler, Paolo Colombo, Christer Hogstrand
Published 2018-02-01

Scientific opinion on the risks for animal and human health related to the presence of quinolizidine alkaloids in feed and food, in particular in lupins and lupin‐derived products...

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Jan Alexander, Bruce Cottrill, Birgit Dusemund, Patrick Mulder, Davide Arcella, Katleen Baert, Claudia Cascio, Hans Steinkellner, Margherita Bignami
Published 2019-11-01