Preface

by Enrico Garaci, Patrizia Popoli
Published 2011-01-01

The role of the Istituto Superiore di Sanità as the competent authority for Phase I trials in the translation of advanced therapies

by Patrizia Popoli, Maria Francesca Cometa, Fulvia Fabi, Annarita Meneguz
Published 2011-01-01

Role of Adenosine A2A Receptors in Modulating Synaptic Functions and Brain Levels of BDNF: a Possible Key Mechanism in the Pathophysiology of Huntington's Disease

by Maria Teresa Tebano, Alberto Martire, Valentina Chiodi, Antonella Ferrante, Patrizia Popoli
Published 2010-01-01

P2X7 Receptor Agonist 2′(3′)-O-(4-Benzoylbenzoyl)ATP Differently Modulates Cell Viability and Corticostriatal Synaptic Transmission in Experimental Models of Huntington’s Disease...

by Alberto Martire, Rita Pepponi, Francesco Liguori, Cinzia Volonté, Cinzia Volonté, Patrizia Popoli
Published 2021-02-01

Insight into the Role of the STriatal-Enriched Protein Tyrosine Phosphatase (STEP) in A2A Receptor-Mediated Effects in the Central Nervous System

by Maria Rosaria Domenici, Cinzia Mallozzi, Rita Pepponi, Ida Casella, Valentina Chiodi, Antonella Ferrante, Patrizia Popoli
Published 2021-04-01

Myelin Defects in Niemann–Pick Type C Disease: Mechanisms and Possible Therapeutic Perspectives

by Antonietta Bernardo, Chiara De Nuccio, Sergio Visentin, Alberto Martire, Luisa Minghetti, Patrizia Popoli, Antonella Ferrante
Published 2021-08-01

Remodeling of striatal NMDA receptors by chronic A2A receptor blockade in Huntington's disease mice

by Alberto Martire, Antonella Ferrante, Rosa Luisa Potenza, Monica Armida, Roberta Ferretti, Antonella Pézzola, Maria Rosaria Domenici, Patrizia Popoli
Published 2010-01-01

The adenosine A2A receptor agonist T1–11 ameliorates neurovisceral symptoms and extends the lifespan of a mouse model of Niemann-Pick type C disease

by Antonella Ferrante, Antonella Pezzola, Andrea Matteucci, Antonella Di Biase, Lucilla Attorri, Monica Armida, Alberto Martire, Yijuang Chern, Patrizia Popoli
Published 2018-02-01

Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington's disease

by Antonella Ferrante, Alberto Martire, Rita Pepponi, Katia Varani, Fabrizio Vincenzi, Luca Ferraro, Sarah Beggiato, Maria Teresa Tebano, Patrizia Popoli
Published 2014-11-01

Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosis

by Savina Apolloni, Susanna Amadio, Chiara Parisi, Alessandra Matteucci, Rosa L. Potenza, Monica Armida, Patrizia Popoli, Nadia D’Ambrosi, Cinzia Volonté
Published 2014-09-01

Adenosine Receptor Heteromers and their Integrative Role in Striatal Function

by Sergi Ferré, Francisco Ciruela, César Quiroz, Rafael Luján, Patrizia Popoli, Rodrigo A. Cunha, Luigi F. Agnati, Kjell Fuxe, Amina S. Woods, Carme Lluis, Rafael Franco
Published 2007-01-01

Adenosine A2A receptor inhibition reduces synaptic and cognitive hippocampal alterations in Fmr1 KO mice

by Antonella Ferrante, Zaira Boussadia, Antonella Borreca, Cinzia Mallozzi, Giorgia Pedini, Laura Pacini, Antonella Pezzola, Monica Armida, Fabrizio Vincenzi, Katia Varani, Claudia Bagni, Patrizia Popoli, Alberto Martire
Published 2021-02-01

Unbalance of CB1 receptors expressed in GABAergic and glutamatergic neurons in a transgenic mouse model of Huntington's disease

by Valentina Chiodi, Motokazu Uchigashima, Sarah Beggiato, Antonella Ferrante, Monica Armida, Alberto Martire, Rosa Luisa Potenza, Luca Ferraro, Sergio Tanganelli, Masahiko Watanabe, Maria Rosaria Domenici, Patrizia Popoli
Published 2012-03-01

A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration.

by Gabriele De Luca, Maria Teresa Russo, Paolo Degan, Cecilia Tiveron, Andrea Zijno, Ettore Meccia, Ilenia Ventura, Elisabetta Mattei, Yusaku Nakabeppu, Marco Crescenzi, Rita Pepponi, Antonella Pèzzola, Patrizia Popoli, Margherita Bignami
Published 2008-11-01

Minocycline in phenotypic models of Huntington's disease

by Kadiombo Bantubungi, Carine Jacquard, Anita Greco, Annita Pintor, Abdelwahed Chtarto, Khalid Tai, Marie-Christine Galas, Liliane Tenenbaum, Nicole Déglon, Patrizia Popoli, Luisa Minghetti, Emmanuel Brouillet, Jacques Brotchi, Marc Levivier, Serge N. Schiffmann, David Blum
Published 2005-02-01

Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial

by Francesco Perrone, Maria Carmela Piccirillo, Paolo Antonio Ascierto, Carlo Salvarani, Roberto Parrella, Anna Maria Marata, Patrizia Popoli, Laurenzia Ferraris, Massimiliano M. Marrocco-Trischitta, Diego Ripamonti, Francesca Binda, Paolo Bonfanti, Nicola Squillace, Francesco Castelli, Maria Lorenza Muiesan, Miriam Lichtner, Carlo Calzetti, Nicola Duccio Salerno, Luigi Atripaldi, Marco Cascella, Massimo Costantini, Giovanni Dolci, Nicola Cosimo Facciolongo, Fiorentino Fraganza, Marco Massari, Vincenzo Montesarchio, Cristina Mussini, Emanuele Alberto Negri, Gerardo Botti, Claudia Cardone, Piera Gargiulo, Adriano Gravina, Clorinda Schettino, Laura Arenare, Paolo Chiodini, Ciro Gallo, the TOCIVID-19 investigators, Italy
Published 2020-10-01