Comprehensive Evaluation of Commercial Bisulfite-Based DNA Methylation Kits and Development of an Alternative Protocol With Improved Conversion Performance

by Sascha Tierling, Beate Schmitt, Jörn Walter
Published 2018-03-01

CpG island mapping by epigenome prediction.

by Christoph Bock, Jörn Walter, Martina Paulsen, Thomas Lengauer
Published 2007-06-01

The Influence of Hydroxylation on Maintaining CpG Methylation Patterns: A Hidden Markov Model Approach.

by Pascal Giehr, Charalampos Kyriakopoulos, Gabriella Ficz, Verena Wolf, Jörn Walter
Published 2016-05-01

CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure.

by Christoph Bock, Martina Paulsen, Sascha Tierling, Thomas Mikeska, Thomas Lengauer, Jörn Walter
Published 2006-03-01

RnBeads 2.0: comprehensive analysis of DNA methylation data

by Fabian Müller, Michael Scherer, Yassen Assenov, Pavlo Lutsik, Jörn Walter, Thomas Lengauer, Christoph Bock
Published 2019-03-01

DNA methylation alterations in iPSC- and hESC-derived neurons: potential implications for neurological disease modeling

by Laura de Boni, Gilles Gasparoni, Carolin Haubenreich, Sascha Tierling, Ina Schmitt, Michael Peitz, Philipp Koch, Jörn Walter, Ullrich Wüllner, Oliver Brüstle
Published 2018-01-01

reChIP-seq reveals widespread bivalency of H3K4me3 and H3K27me3 in CD4+ memory T cells

by Sarah Kinkley, Johannes Helmuth, Julia K. Polansky, Ilona Dunkel, Gilles Gasparoni, Sebastian Fröhler, Wei Chen, Jörn Walter, Alf Hamann, Ho-Ryun Chung
Published 2016-08-01

The composition of the pulmonary microbiota in sarcoidosis – an observational study

by André Becker, Giovanna Vella, Valentina Galata, Katharina Rentz, Christoph Beisswenger, Christian Herr, Jörn Walter, Sascha Tierling, Hortense Slevogt, Andreas Keller, Robert Bals
Published 2019-02-01

In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases.

by Julia Arand, David Spieler, Tommy Karius, Miguel R Branco, Daniela Meilinger, Alexander Meissner, Thomas Jenuwein, Guoliang Xu, Heinrich Leonhardt, Verena Wolf, Jörn Walter
Published 2012-06-01

DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution.

by Yingying Zhang, Christian Rohde, Sascha Tierling, Tomasz P Jurkowski, Christoph Bock, Diana Santacruz, Sergey Ragozin, Richard Reinhardt, Marco Groth, Jörn Walter, Albert Jeltsch
Published 2009-03-01

DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis

by Nicole Y. Souren, Lisa A. Gerdes, Pavlo Lutsik, Gilles Gasparoni, Eduardo Beltrán, Abdulrahman Salhab, Tania Kümpfel, Dieter Weichenhan, Christoph Plass, Reinhard Hohlfeld, Jörn Walter
Published 2019-05-01

Antisense Oligonucleotide- and CRISPR-Cas9-Mediated Rescue of mRNA Splicing for a Deep Intronic CLRN1 Mutation

by Anna-Lena Panagiotopoulos, Nina Karguth, Marina Pavlou, Sybille Böhm, Gilles Gasparoni, Jörn Walter, Alexander Graf, Helmut Blum, Martin Biel, Lisa Maria Riedmayr, Elvir Becirovic
Published 2020-09-01

Human cytomegalovirus drives epigenetic imprinting of the IFNG locus in NKG2Chi natural killer cells.

by Merlin Luetke-Eversloh, Quirin Hammer, Pawel Durek, Karl Nordström, Gilles Gasparoni, Matthias Pink, Alf Hamann, Jörn Walter, Hyun-Dong Chang, Jun Dong, Chiara Romagnani
Published 2014-10-01

Points-to-consider on the return of results in epigenetic research

by Stephanie O. M. Dyke, Katie M. Saulnier, Charles Dupras, Amy P. Webster, Karen Maschke, Mark Rothstein, Reiner Siebert, Jörn Walter, Stephan Beck, Tomi Pastinen, Yann Joly
Published 2019-05-01

CD137+CD154− Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from In Vitro Expansion Cultures

by Anna Nowak, Dominik Lock, Petra Bacher, Thordis Hohnstein, Katrin Vogt, Judith Gottfreund, Pascal Giehr, Julia K. Polansky, Birgit Sawitzki, Andrew Kaiser, Jörn Walter, Alexander Scheffold, Alexander Scheffold
Published 2018-02-01

Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

by Michael Scherer, Gilles Gasparoni, Souad Rahmouni, Tatiana Shashkova, Marion Arnoux, Edouard Louis, Arina Nostaeva, Diana Avalos, Emmanouil T. Dermitzakis, Yurii S. Aulchenko, Thomas Lengauer, Paul A. Lyons, Michel Georges, Jörn Walter
Published 2021-09-01

MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs

by Mélanie A. Eckersley-Maslin, Valentine Svensson, Christel Krueger, Thomas M. Stubbs, Pascal Giehr, Felix Krueger, Ricardo J. Miragaia, Charalampos Kyriakopoulos, Rebecca V. Berrens, Inês Milagre, Jörn Walter, Sarah A. Teichmann, Wolf Reik
Published 2016-09-01

A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains

by Abdulrahman Salhab, Karl Nordström, Gilles Gasparoni, Kathrin Kattler, Peter Ebert, Fidel Ramirez, Laura Arrigoni, Fabian Müller, Julia K. Polansky, Cristina Cadenas, Jan G.Hengstler, Thomas Lengauer, Thomas Manke, DEEP Consortium, Jörn Walter
Published 2018-09-01

Blockage of the Epithelial-to-Mesenchymal Transition Is Required for Embryonic Stem Cell Derivation

by Mehdi Totonchi, Seyedeh-Nafiseh Hassani, Ali Sharifi-Zarchi, Natalia Tapia, Kenjiro Adachi, Julia Arand, Boris Greber, Davood Sabour, Marcos J. Araúzo-Bravo, Jörn Walter, Mohammad Pakzad, Hamid Gourabi, Hans R. Schöler, Hossein Baharvand
Published 2017-10-01

DNA methylation-based prediction of response to immune checkpoint inhibition in metastatic melanoma

by Bastian Schilling, Sascha Tierling, Jörn Walter, Katharina Filipski, Michael Scherer, Kim N. Zeiner, Andreas Bucher, Johannes Kleemann, Philipp Jurmeister, Tabea I. Hartung, Markus Meissner, Karl H. Plate, Tim R. Fenton, Pia S. Zeiner, Patrick N. Harter
Published 2021-07-01