Global DNA hypomethylation prevents consolidation of differentiation programs and allows reversion to the embryonic stem cell state.

by Christine S Schmidt, Sebastian Bultmann, Daniela Meilinger, Benedikt Zacher, Achim Tresch, Kerstin C Maier, Christian Peter, Dietmar E Martin, Heinrich Leonhardt, Fabio Spada
Published 2012-01-01

Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1.

by Carina Frauer, Andrea Rottach, Daniela Meilinger, Sebastian Bultmann, Karin Fellinger, Stefan Hasenöder, Mengxi Wang, Weihua Qin, Johannes Söding, Fabio Spada, Heinrich Leonhardt
Published 2011-02-01

In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases.

by Julia Arand, David Spieler, Tommy Karius, Miguel R Branco, Daniela Meilinger, Alexander Meissner, Thomas Jenuwein, Guoliang Xu, Heinrich Leonhardt, Verena Wolf, Jörn Walter
Published 2012-06-01