Knowledge-primed neural networks enable biologically interpretable deep learning on single-cell sequencing data

by Nikolaus Fortelny, Christoph Bock
Published 2020-08-01

CpG island mapping by epigenome prediction.

by Christoph Bock, Jörn Walter, Martina Paulsen, Thomas Lengauer
Published 2007-06-01

CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure.

by Christoph Bock, Martina Paulsen, Sascha Tierling, Thomas Mikeska, Thomas Lengauer, Jörn Walter
Published 2006-03-01

Spontaneously Resolved Atopic Dermatitis Shows Melanocyte and Immune Cell Activation Distinct From Healthy Control Skin

by Katharina Rindler, Thomas Krausgruber, Felix M. Thaler, Natalia Alkon, Christine Bangert, Harald Kurz, Nikolaus Fortelny, Thomas B. Rojahn, Constanze Jonak, Johannes Griss, Christoph Bock, Christoph Bock, Patrick M. Brunner
Published 2021-02-01

RnBeads 2.0: comprehensive analysis of DNA methylation data

by Fabian Müller, Michael Scherer, Yassen Assenov, Pavlo Lutsik, Jörn Walter, Thomas Lengauer, Christoph Bock
Published 2019-03-01

Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets

by Brenda Marquina-Sanchez, Nikolaus Fortelny, Matthias Farlik, Andhira Vieira, Patrick Collombat, Christoph Bock, Stefan Kubicek
Published 2020-05-01

Single-Cell DNA Methylome Sequencing and Bioinformatic Inference of Epigenomic Cell-State Dynamics

by Matthias Farlik, Nathan C. Sheffield, Angelo Nuzzo, Paul Datlinger, Andreas Schönegger, Johanna Klughammer, Christoph Bock
Published 2015-03-01

Complex Interplay Between MAZR and Runx3 Regulates the Generation of Cytotoxic T Lymphocyte and Memory T Cells

by Alexandra Franziska Gülich, Ramona Rica, Caroline Tizian, Csilla Viczenczova, Kseniya Khamina, Thomas Faux, Daniela Hainberger, Thomas Penz, Remy Bosselut, Christoph Bock, Christoph Bock, Asta Laiho, Laura L. Elo, Andreas Bergthaler, Wilfried Ellmeier, Shinya Sakaguchi
Published 2021-03-01

Differential DNA Methylation Analysis without a Reference Genome

by Johanna Klughammer, Paul Datlinger, Dieter Printz, Nathan C. Sheffield, Matthias Farlik, Johanna Hadler, Gerhard Fritsch, Christoph Bock
Published 2015-12-01

NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4+ T Cells

by Daniela Hainberger, Valentina Stolz, Ci Zhu, Michael Schuster, Lena Müller, Patricia Hamminger, Ramona Rica, Darina Waltenberger, Marlis Alteneder, Thomas Krausgruber, Anastasiya Hladik, Sylvia Knapp, Sylvia Knapp, Christoph Bock, Christoph Bock, Michael Trauner, Michael A. Farrar, Wilfried Ellmeier
Published 2020-04-01

Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks

by André F. Rendeiro, Christian Schmidl, Jonathan C. Strefford, Renata Walewska, Zadie Davis, Matthias Farlik, David Oscier, Christoph Bock
Published 2016-06-01

The human genomic melting map.

by Fang Liu, Eivind Tøstesen, Jostein K Sundet, Tor-Kristian Jenssen, Christoph Bock, Geir Ivar Jerstad, William G Thilly, Eivind Hovig
Published 2007-05-01

Epigenome Mapping Reveals Distinct Modes of Gene Regulation and Widespread Enhancer Reprogramming by the Oncogenic Fusion Protein EWS-FLI1

by Eleni M. Tomazou, Nathan C. Sheffield, Christian Schmidl, Michael Schuster, Andreas Schönegger, Paul Datlinger, Stefan Kubicek, Christoph Bock, Heinrich Kovar
Published 2015-02-01

DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution.

by Yingying Zhang, Christian Rohde, Sascha Tierling, Tomasz P Jurkowski, Christoph Bock, Diana Santacruz, Sergey Ragozin, Richard Reinhardt, Marco Groth, Jörn Walter, Albert Jeltsch
Published 2009-03-01

High-throughput drug screening identifies the ATR-CHK1 pathway as a therapeutic vulnerability of CALR mutated hematopoietic cells

by Ruochen Jia, Leon Kutzner, Anna Koren, Kathrin Runggatscher, Peter Májek, André C. Müller, Michael Schuster, Christoph Bock, Joanna I. Loizou, Stefan Kubicek, Robert Kralovics
Published 2021-07-01

Spinal Deformities after Childhood Tumors

by Anna K. Hell, Ingrid Kühnle, Heiko M. Lorenz, Lena Braunschweig, Katja A. Lüders, Hans Christoph Bock, Christof M. Kramm, Hans Christoph Ludwig, Konstantinos Tsaknakis
Published 2020-11-01

Structural and functional insights into the interaction and targeting hub TMD0 of the polypeptide transporter TAPL

by Christoph Bock, Frank Löhr, Franz Tumulka, Katrin Reichel, Julia Würz, Gerhard Hummer, Lars Schäfer, Robert Tampé, Benesh Joseph, Frank Bernhard, Volker Dötsch, Rupert Abele
Published 2018-10-01

Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors

by Aline C Planello, Junfeng Ji, Vivek Sharma, Rajat Singhania, Faridah Mbabaali, Fabian Müller, Javier A Alfaro, Christoph Bock, Daniel D De Carvalho, Nizar N Batada
Published 2014-01-01

Genomic distribution and inter-sample variation of non-CpG methylation across human cell types.

by Michael J Ziller, Fabian Müller, Jing Liao, Yingying Zhang, Hongcang Gu, Christoph Bock, Patrick Boyle, Charles B Epstein, Bradley E Bernstein, Thomas Lengauer, Andreas Gnirke, Alexander Meissner
Published 2011-12-01

Empfehlungen für die Umsetzung von Open Access in Österreich

by Bruno Bauer, Guido Blechl, Christoph Bock, Patrick Danowski, Andreas Ferus, Anton Graschopf, Thomas König, Katja Mayer, Michael Nentwich, Falk Reckling, Katharina Rieck, Peter Seitz, Herwig Stöger, Elvira Welzig
Published 2015-01-01