Fundamental differences

by Peter W Gunning, Edna C Hardeman
Published 2018-02-01

SUMOylation of GTF2IRD1 regulates protein partner interactions and ubiquitin-mediated degradation.

by Jocelyn Widagdo, Kylie M Taylor, Peter W Gunning, Edna C Hardeman, Stephen J Palmer
Published 2012-01-01

Developmental Profiling of Tropomyosin Expression in Mouse Brain Reveals Tpm4.2 as the Major Post-synaptic Tropomyosin in the Mature Brain

by Alexandra K. Suchowerska, Sandra Fok, Holly Stefen, Holly Stefen, Peter W. Gunning, Edna C. Hardeman, John Power, Thomas Fath, Thomas Fath
Published 2017-12-01

Combined MRI and ³¹P-MRS investigations of the ACTA1(H40Y) mouse model of nemaline myopathy show impaired muscle function and altered energy metabolism.

by Charlotte Gineste, Yann Le Fur, Christophe Vilmen, Arnaud Le Troter, Emilie Pecchi, Patrick J Cozzone, Edna C Hardeman, David Bendahan, Julien Gondin
Published 2013-01-01

Recruitment Kinetics of Tropomyosin Tpm3.1 to Actin Filament Bundles in the Cytoskeleton Is Independent of Actin Filament Kinetics.

by Mark A Appaduray, Andrius Masedunskas, Nicole S Bryce, Christine A Lucas, Sean C Warren, Paul Timpson, Jeffrey H Stear, Peter W Gunning, Edna C Hardeman
Published 2016-01-01

Alterations at the cross-bridge level are associated with a paradoxical gain of muscle function in vivo in a mouse model of nemaline myopathy.

by Charlotte Gineste, Coen Ottenheijm, Yann Le Fur, Sébastien Banzet, Emilie Pecchi, Christophe Vilmen, Patrick J Cozzone, Nathalie Koulmann, Edna C Hardeman, David Bendahan, Julien Gondin
Published 2014-01-01

Tropomyosin Tpm3.1 Is Required to Maintain the Structure and Function of the Axon Initial Segment

by Amr Abouelezz, Holly Stefen, Mikael Segerstråle, David Micinski, Rimante Minkeviciene, Lauri Lahti, Edna C. Hardeman, Peter W. Gunning, Casper C. Hoogenraad, Tomi Taira, Thomas Fath, Pirta Hotulainen
Published 2020-05-01

Cell elasticity is regulated by the tropomyosin isoform composition of the actin cytoskeleton.

by Iman Jalilian, Celine Heu, Hong Cheng, Hannah Freittag, Melissa Desouza, Justine R Stehn, Nicole S Bryce, Renee M Whan, Edna C Hardeman, Thomas Fath, Galina Schevzov, Peter W Gunning
Published 2015-01-01

Mutation of Gtf2ird1 from the Williams–Beuren syndrome critical region results in facial dysplasia, motor dysfunction, and altered vocalisations

by Monique L. Howard, Stephen J. Palmer, Kylie M. Taylor, Geoffrey J. Arthurson, Matthew W. Spitzer, Xin Du, Terence Y.C. Pang, Thibault Renoir, Edna C. Hardeman, Anthony J. Hannan
Published 2012-03-01

A robust method for particulate detection of a genetic tag for 3D electron microscopy

by James Rae, Charles Ferguson, Nicholas Ariotti, Richard I Webb, Han-Hao Cheng, James L Mead, James D Riches, Dominic JB Hunter, Nick Martel, Joanne Baltos, Arthur Christopoulos, Nicole S Bryce, Maria Lastra Cagigas, Sachini Fonseka, Marcel E Sayre, Edna C Hardeman, Peter W Gunning, Yann Gambin, Thomas E Hall, Robert G Parton
Published 2021-04-01

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue

by Zahra Erami, David Herrmann, Sean C. Warren, Max Nobis, Ewan J. McGhee, Morghan C. Lucas, Wilfred Leung, Nadine Reischmann, Agata Mrowinska, Juliane P. Schwarz, Shereen Kadir, James R.W. Conway, Claire Vennin, Saadia A. Karim, Andrew D. Campbell, David Gallego-Ortega, Astrid Magenau, Kendelle J. Murphy, Rachel A. Ridgway, Andrew M. Law, Stacey N. Walters, Shane T. Grey, David R. Croucher, Lei Zhang, Herbert Herzog, Edna C. Hardeman, Peter W. Gunning, Christopher J. Ormandy, T.R. Jeffry Evans, Douglas Strathdee, Owen J. Sansom, Jennifer P. Morton, Kurt I. Anderson, Paul Timpson
Published 2016-01-01

A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts

by Max Nobis, David Herrmann, Sean C. Warren, Shereen Kadir, Wilfred Leung, Monica Killen, Astrid Magenau, David Stevenson, Morghan C. Lucas, Nadine Reischmann, Claire Vennin, James R.W. Conway, Alice Boulghourjian, Anaiis Zaratzian, Andrew M. Law, David Gallego-Ortega, Christopher J. Ormandy, Stacey N. Walters, Shane T. Grey, Jacqueline Bailey, Tatyana Chtanova, Julian M.W. Quinn, Paul A. Baldock, Peter I. Croucher, Juliane P. Schwarz, Agata Mrowinska, Lei Zhang, Herbert Herzog, Andrius Masedunskas, Edna C. Hardeman, Peter W. Gunning, Gonzalo del Monte-Nieto, Richard P. Harvey, Michael S. Samuel, Marina Pajic, Ewan J. McGhee, Anna-Karin E. Johnsson, Owen J. Sansom, Heidi C.E. Welch, Jennifer P. Morton, Douglas Strathdee, Kurt I. Anderson, Paul Timpson
Published 2017-10-01