Intravital imaging reveals new ancillary mechanisms co-opted by cancer cells to drive tumor progression [version 1; referees: 2 approved]

by Claire Vennin, David Herrmann, Morghan C. Lucas, Paul Timpson
Published 2016-05-01

There are four dynamically and functionally distinct populations of E-cadherin in cell junctions

by Zahra Erami, Paul Timpson, Wu Yao, Ronen Zaidel-Bar, Kurt I. Anderson
Published 2015-11-01

Dynamic Stromal Alterations Influence Tumor-Stroma Crosstalk to Promote Pancreatic Cancer and Treatment Resistance

by Kendelle J. Murphy, Cecilia R. Chambers, David Herrmann, Paul Timpson, Brooke A. Pereira
Published 2021-07-01

Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation

by Neophytos Christodoulou, Antonia Weberling, Douglas Strathdee, Kurt I. Anderson, Paul Timpson, Magdalena Zernicka-Goetz
Published 2019-08-01

Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration

by Hadir Marei, Alejandro Carpy, Anna Woroniuk, Claire Vennin, Gavin White, Paul Timpson, Boris Macek, Angeliki Malliri
Published 2016-02-01

Recent advances in understanding the complexities of metastasis [version 2; referees: 3 approved]

by Jessica L. Chitty, Elysse C. Filipe, Morghan C. Lucas, David Herrmann, Thomas R. Cox, Paul Timpson
Published 2018-09-01

Recent advances in understanding the complexities of metastasis [version 1; referees: 3 approved]

by Jessica L. Chitty, Elysse C. Filipe, Morghan C. Lucas, David Herrmann, Thomas R. Cox, Paul Timpson
Published 2018-08-01

The Evolving Understanding of the Molecular and Therapeutic Landscape of Pancreatic Ductal Adenocarcinoma

by Ashleigh Parkin, Jennifer Man, Angela Chou, Adnan M Nagrial, Jaswinder Samra, Anthony J Gill, Paul Timpson, Marina Pajic
Published 2018-11-01

Live Cell in Vitro and in Vivo Imaging Applications: Accelerating Drug Discovery

by Neil O Carragher, Valerie G Brunton, Alan Serrels, Kurt I Anderson, Marta Canel, Paul Timpson, Ewan J McGhee, Beverley Isherwood
Published 2011-04-01

Recruitment Kinetics of Tropomyosin Tpm3.1 to Actin Filament Bundles in the Cytoskeleton Is Independent of Actin Filament Kinetics.

by Mark A Appaduray, Andrius Masedunskas, Nicole S Bryce, Christine A Lucas, Sean C Warren, Paul Timpson, Jeffrey H Stear, Peter W Gunning, Edna C Hardeman
Published 2016-01-01

Single cell transcriptome atlas of mouse mammary epithelial cells across development

by Bhupinder Pal, Yunshun Chen, Michael J. G. Milevskiy, François Vaillant, Lexie Prokopuk, Caleb A. Dawson, Bianca D. Capaldo, Xiaoyu Song, Felicity Jackling, Paul Timpson, Geoffrey J. Lindeman, Gordon K. Smyth, Jane E. Visvader
Published 2021-06-01

A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma

by Alvaro Gonzalez Rajal, Kamila A Marzec, Rachael A McCloy, Max Nobis, Venessa Chin, Jordan F Hastings, Kaitao Lai, Marina Kennerson, William E Hughes, Vijesh Vaghjiani, Paul Timpson, Jason E Cain, D Neil Watkins, David R Croucher, Andrew Burgess
Published 2021-05-01

Ex vivo culture of intact human patient derived pancreatic tumour tissue

by John Kokkinos, George Sharbeen, Koroush S. Haghighi, Rosa Mistica C. Ignacio, Chantal Kopecky, Estrella Gonzales-Aloy, Janet Youkhana, Paul Timpson, Brooke A. Pereira, Shona Ritchie, Elvis Pandzic, Cyrille Boyer, Thomas P. Davis, Lisa M. Butler, David Goldstein, Joshua A. McCarroll, Phoebe A. Phillips
Published 2021-01-01

CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer

by Murugan Kalimutho, Debottam Sinha, Jessie Jeffery, Katia Nones, Sriganesh Srihari, Winnie C Fernando, Pascal HG Duijf, Claire Vennin, Prahlad Raninga, Devathri Nanayakkara, Deepak Mittal, Jodi M Saunus, Sunil R Lakhani, J Alejandro López, Kevin J Spring, Paul Timpson, Brian Gabrielli, Nicola Waddell, Kum Kum Khanna
Published 2018-09-01

Removing physiological motion from intravital and clinical functional imaging data

by Sean C Warren, Max Nobis, Astrid Magenau, Yousuf H Mohammed, David Herrmann, Imogen Moran, Claire Vennin, James RW Conway, Pauline Mélénec, Thomas R Cox, Yingxiao Wang, Jennifer P Morton, Heidi CE Welch, Douglas Strathdee, Kurt I Anderson, Tri Giang Phan, Michael S Roberts, Paul Timpson
Published 2018-07-01

ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling

by Andreia V. Pinho, Mathias Van Bulck, Lorraine Chantrill, Mehreen Arshi, Tatyana Sklyarova, David Herrmann, Claire Vennin, David Gallego-Ortega, Amanda Mawson, Marc Giry-Laterriere, Astrid Magenau, Gunther Leuckx, Luc Baeyens, Anthony J. Gill, Phoebe Phillips, Paul Timpson, Andrew V. Biankin, Jianmin Wu, Ilse Rooman
Published 2018-11-01

∆133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling

by Hamish Campbell, Nicholas Fleming, Imogen Roth, Sunali Mehta, Anna Wiles, Gail Williams, Claire Vennin, Nikola Arsic, Ashleigh Parkin, Marina Pajic, Fran Munro, Les McNoe, Michael Black, John McCall, Tania L. Slatter, Paul Timpson, Roger Reddel, Pierre Roux, Cristin Print, Margaret A. Baird, Antony W. Braithwaite
Published 2018-01-01

The Rac-FRET Mouse Reveals Tight Spatiotemporal Control of Rac Activity in Primary Cells and Tissues

by Anna-Karin E. Johnsson, Yanfeng Dai, Max Nobis, Martin J. Baker, Ewan J. McGhee, Simon Walker, Juliane P. Schwarz, Shereen Kadir, Jennifer P. Morton, Kevin B. Myant, David J. Huels, Anne Segonds-Pichon, Owen J. Sansom, Kurt I. Anderson, Paul Timpson, Heidi C.E. Welch
Published 2014-03-01

Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity

by Chenxu Yan, Tianshu Zeng, Kailun Lee, Max Nobis, Kim Loh, Luoning Gou, Zefeng Xia, Zhongmin Gao, Mohammed Bensellam, Will Hughes, Jackie Lau, Lei Zhang, Chi Kin Ip, Ronaldo Enriquez, Hanyu Gao, Qiao-Ping Wang, Qi Wu, Jody J. Haigh, D. Ross Laybutt, Paul Timpson, Herbert Herzog, Yan-Chuan Shi
Published 2021-05-01

Cholesterol Regulates Syntaxin 6 Trafficking at trans-Golgi Network Endosomal Boundaries

by Meritxell Reverter, Carles Rentero, Ana Garcia-Melero, Monira Hoque, Sandra Vilà de Muga, Anna Álvarez-Guaita, James R.W. Conway, Peta Wood, Rose Cairns, Lilia Lykopoulou, Daniel Grinberg, Lluïsa Vilageliu, Marta Bosch, Joerg Heeren, Juan Blasi, Paul Timpson, Albert Pol, Francesc Tebar, Rachael Z. Murray, Thomas Grewal, Carlos Enrich
Published 2014-05-01