Single-Cell Transcriptomics in Cancer Immunobiology: The Future of Precision Oncology

by Fatima Valdes-Mora, Fatima Valdes-Mora, Kristina Handler, Andrew M. K. Law, Robert Salomon, Samantha R. Oakes, Samantha R. Oakes, Christopher J. Ormandy, Christopher J. Ormandy, David Gallego-Ortega, David Gallego-Ortega
Published 2018-11-01

A missense mutation in the transcription factor ETV5 leads to sterility, increased embryonic and perinatal death, postnatal growth restriction, renal asymmetry and polydactyly in t...

by Duangporn Jamsai, Brett J Clark, Stephanie J Smith, Belinda Whittle, Christopher C Goodnow, Christopher J Ormandy, Moira K O'Bryan
Published 2013-01-01

Meta-analysis and gene set enrichment relative to er status reveal elevated activity of MYC and E2F in the "basal" breast cancer subgroup.

by M Chehani Alles, Margaret Gardiner-Garden, David J Nott, Yixin Wang, John A Foekens, Robert L Sutherland, Elizabeth A Musgrove, Christopher J Ormandy
Published 2009-01-01

RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility.

by Moira K O'Bryan, Brett J Clark, Eileen A McLaughlin, Rebecca J D'Sylva, Liza O'Donnell, Jacqueline A Wilce, Jessie Sutherland, Anne E O'Connor, Belinda Whittle, Christopher C Goodnow, Christopher J Ormandy, Duangporn Jamsai
Published 2013-01-01

Identification of functional networks of estrogen- and c-Myc-responsive genes and their relationship to response to tamoxifen therapy in breast cancer.

by Elizabeth A Musgrove, C Marcelo Sergio, Sherene Loi, Claire K Inman, Luke R Anderson, M Chehani Alles, Mark Pinese, C Elizabeth Caldon, Judith Schütte, Margaret Gardiner-Garden, Christopher J Ormandy, Grant McArthur, Alison J Butt, Robert L Sutherland
Published 2008-01-01

ELF5 modulates the estrogen receptor cistrome in breast cancer.

by Catherine L Piggin, Daniel L Roden, Andrew M K Law, Mark P Molloy, Christoph Krisp, Alexander Swarbrick, Matthew J Naylor, Maria Kalyuga, Warren Kaplan, Samantha R Oakes, David Gallego-Ortega, Susan J Clark, Jason S Carroll, Nenad Bartonicek, Christopher J Ormandy
Published 2020-01-01

Correction: HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.

by Shu Ly Lim, Zhi Peng Qu, R Daniel Kortschak, David M Lawrence, Joel Geoghegan, Anna-Lena Hempfling, Martin Bergmann, Christopher C Goodnow, Christopher J Ormandy, Lee Wong, Jeff Mann, Hamish S Scott, Duangporn Jamsai, David L Adelson, Moira K O'Bryan
Published 2015-12-01

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.

by Jennifer C Y Lo, Duangporn Jamsai, Anne E O'Connor, Claire Borg, Brett J Clark, James C Whisstock, Mark C Field, Vicki Adams, Tomomoto Ishikawa, R John Aitken, Belinda Whittle, Christopher C Goodnow, Christopher J Ormandy, Moira K O'Bryan
Published 2012-01-01

HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.

by Shu Ly Lim, Zhi Peng Qu, R Daniel Kortschak, David M Lawrence, Joel Geoghegan, Anna-Lena Hempfling, Martin Bergmann, Christopher C Goodnow, Christopher J Ormandy, Lee Wong, Jeff Mann, Hamish S Scott, Duangporn Jamsai, David L Adelson, Moira K O'Bryan
Published 2015-10-01

Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB

by Holly Holliday, Daniel Roden, Simon Junankar, Sunny Z. Wu, Laura A. Baker, Christoph Krisp, Chia-Ling Chan, Andrea McFarland, Joanna N. Skhinas, Thomas R. Cox, Bhupinder Pal, Nicholas D. Huntington, Christopher J. Ormandy, Jason S. Carroll, Jane Visvader, Mark P. Molloy, Alexander Swarbrick
Published 2021-02-01

LRGUK-1 is required for basal body and manchette function during spermatogenesis and male fertility.

by Yan Liu, Kathleen DeBoer, David M de Kretser, Liza O'Donnell, Anne E O'Connor, D Jo Merriner, Hidenobu Okuda, Belinda Whittle, David A Jans, Athina Efthymiadis, Robert I McLachlan, Christopher J Ormandy, Chris C Goodnow, Duangporn Jamsai, Moira K O'Bryan
Published 2015-03-01

Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1

by Wee S. Teo, Wee S. Teo, Holly Holliday, Holly Holliday, Nitheesh Karthikeyan, Aurélie S. Cazet, Aurélie S. Cazet, Daniel L. Roden, Daniel L. Roden, Kate Harvey, Christina Valbirk Konrad, Reshma Murali, Binitha Anu Varghese, Archana P. Thankamony, Archana P. Thankamony, Chia-Ling Chan, Chia-Ling Chan, Andrea McFarland, Simon Junankar, Simon Junankar, Sunny Ye, Jessica Yang, Iva Nikolic, Iva Nikolic, Jaynish S. Shah, Laura A. Baker, Laura A. Baker, Ewan K. A. Millar, Ewan K. A. Millar, Ewan K. A. Millar, Ewan K. A. Millar, Matthew J. Naylor, Matthew J. Naylor, Matthew J. Naylor, Christopher J. Ormandy, Christopher J. Ormandy, Sunil R. Lakhani, Warren Kaplan, Warren Kaplan, Albert S. Mellick, Albert S. Mellick, Sandra A. O'Toole, Sandra A. O'Toole, Alexander Swarbrick, Alexander Swarbrick, Radhika Nair, Radhika Nair, Radhika Nair
Published 2020-07-01

A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation.

by Samantha R Oakes, David Gallego-Ortega, Prudence M Stanford, Simon Junankar, Wendy Wing Yee Au, Zoya Kikhtyak, Anita von Korff, Claudio M Sergio, Andrew M K Law, Lesley E Castillo, Stephanie L Allerdice, Adelaide I J Young, Catherine Piggin, Belinda Whittle, Edward Bertram, Matthew J Naylor, Daniel L Roden, Jesse Donovan, Alexei Korennykh, Christopher C Goodnow, Moira K O'Bryan, Christopher J Ormandy
Published 2017-11-01

Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer

by Laura A. Baker, Holly Holliday, Daniel Roden, Christoph Krisp, Sunny Z. Wu, Simon Junankar, Aurelien A. Serandour, Hisham Mohammed, Radhika Nair, Geetha Sankaranarayanan, Andrew M. K. Law, Andrea McFarland, Peter T. Simpson, Sunil Lakhani, Eoin Dodson, Christina Selinger, Lyndal Anderson, Goli Samimi, Neville F. Hacker, Elgene Lim, Christopher J. Ormandy, Matthew J. Naylor, Kaylene Simpson, Iva Nikolic, Sandra O’Toole, Warren Kaplan, Mark J. Cowley, Jason S. Carroll, Mark Molloy, Alexander Swarbrick
Published 2020-06-01

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.

by Maria Kalyuga, David Gallego-Ortega, Heather J Lee, Daniel L Roden, Mark J Cowley, C Elizabeth Caldon, Andrew Stone, Stephanie L Allerdice, Fatima Valdes-Mora, Rosalind Launchbury, Aaron L Statham, Nicola Armstrong, M Chehani Alles, Adelaide Young, Andrea Egger, Wendy Au, Catherine L Piggin, Cara J Evans, Anita Ledger, Tilman Brummer, Samantha R Oakes, Warren Kaplan, Julia M W Gee, Robert I Nicholson, Robert L Sutherland, Alexander Swarbrick, Matthew J Naylor, Susan J Clark, Jason S Carroll, Christopher J Ormandy
Published 2012-01-01

ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.

by David Gallego-Ortega, Anita Ledger, Daniel L Roden, Andrew M K Law, Astrid Magenau, Zoya Kikhtyak, Christina Cho, Stephanie L Allerdice, Heather J Lee, Fatima Valdes-Mora, David Herrmann, Robert Salomon, Adelaide I J Young, Brian Y Lee, C Marcelo Sergio, Warren Kaplan, Catherine Piggin, James R W Conway, Brian Rabinovich, Ewan K A Millar, Samantha R Oakes, Tatyana Chtanova, Alexander Swarbrick, Matthew J Naylor, Sandra O'Toole, Andrew R Green, Paul Timpson, Julia M W Gee, Ian O Ellis, Susan J Clark, Christopher J Ormandy
Published 2015-12-01

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue

by Zahra Erami, David Herrmann, Sean C. Warren, Max Nobis, Ewan J. McGhee, Morghan C. Lucas, Wilfred Leung, Nadine Reischmann, Agata Mrowinska, Juliane P. Schwarz, Shereen Kadir, James R.W. Conway, Claire Vennin, Saadia A. Karim, Andrew D. Campbell, David Gallego-Ortega, Astrid Magenau, Kendelle J. Murphy, Rachel A. Ridgway, Andrew M. Law, Stacey N. Walters, Shane T. Grey, David R. Croucher, Lei Zhang, Herbert Herzog, Edna C. Hardeman, Peter W. Gunning, Christopher J. Ormandy, T.R. Jeffry Evans, Douglas Strathdee, Owen J. Sansom, Jennifer P. Morton, Kurt I. Anderson, Paul Timpson
Published 2016-01-01

A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts

by Max Nobis, David Herrmann, Sean C. Warren, Shereen Kadir, Wilfred Leung, Monica Killen, Astrid Magenau, David Stevenson, Morghan C. Lucas, Nadine Reischmann, Claire Vennin, James R.W. Conway, Alice Boulghourjian, Anaiis Zaratzian, Andrew M. Law, David Gallego-Ortega, Christopher J. Ormandy, Stacey N. Walters, Shane T. Grey, Jacqueline Bailey, Tatyana Chtanova, Julian M.W. Quinn, Paul A. Baldock, Peter I. Croucher, Juliane P. Schwarz, Agata Mrowinska, Lei Zhang, Herbert Herzog, Andrius Masedunskas, Edna C. Hardeman, Peter W. Gunning, Gonzalo del Monte-Nieto, Richard P. Harvey, Michael S. Samuel, Marina Pajic, Ewan J. McGhee, Anna-Karin E. Johnsson, Owen J. Sansom, Heidi C.E. Welch, Jennifer P. Morton, Douglas Strathdee, Kurt I. Anderson, Paul Timpson
Published 2017-10-01