Transcriptional Targeting of Mature Dendritic Cells with Adenoviral Vectors via a Modular Promoter System for Antigen Expression and Functional Manipulation

by Ilka Knippertz, Andrea Deinzer, Jan Dörrie, Niels Schaft, Dirk M. Nettelbeck, Alexander Steinkasserer
Published 2016-01-01

Replication and virus-induced transcriptome of HAdV-5 in normal host cells versus cancer cells--differences of relevance for adenoviral oncolysis.

by Dominik E Dorer, Frank Holtrup, Kurt Fellenberg, Johanna K Kaufmann, Sarah Engelhardt, Jörg D Hoheisel, Dirk M Nettelbeck
Published 2011-01-01

Moving oncolytic viruses into the clinic: clinical-grade production, purification, and characterization of diverse oncolytic viruses

by Guy Ungerechts, Sascha Bossow, Barbara Leuchs, Per S Holm, Jean Rommelaere, Matt Coffey, Rob Coffin, John Bell, Dirk M Nettelbeck
Published 2016-01-01

Adenoviruses using the cancer marker EphA2 as a receptor in vitro and in vivo by genetic ligand insertion into different capsid scaffolds.

by Michael Behr, Johanna K Kaufmann, Patrick Ketzer, Sarah Engelhardt, Martin Mück-Häusl, Pamela M Okun, Gabriele Petersen, Frank Neipel, Jessica C Hassel, Anja Ehrhardt, Alexander H Enk, Dirk M Nettelbeck
Published 2014-01-01

Oncolytic Adenoviruses Armed with Tumor Necrosis Factor Alpha and Interleukin-2 Enable Successful Adoptive Cell Therapy

by Riikka Havunen, Mikko Siurala, Suvi Sorsa, Susanna Grönberg-Vähä-Koskela, Michael Behr, Siri Tähtinen, João Manuel Santos, Pauliina Karell, Juuso Rusanen, Dirk M. Nettelbeck, Anja Ehrhardt, Anna Kanerva, Akseli Hemminki
Published 2017-03-01

German Cancer Consortium (DKTK) – A national consortium for translational cancer research

by Stefan Joos, Dirk M. Nettelbeck, Anette Reil‐Held, Katja Engelmann, Alexandra Moosmann, Angelika Eggert, Wolfgang Hiddemann, Mechthild Krause, Christoph Peters, Martin Schuler, Klaus Schulze‐Osthoff, Hubert Serve, Wolfgang Wick, Josef Puchta, Michael Baumann
Published 2019-03-01

Virotherapy in Germany—Recent Activities in Virus Engineering, Preclinical Development, and Clinical Studies

by Dirk M. Nettelbeck, Mathias F. Leber, Jennifer Altomonte, Assia Angelova, Julia Beil, Susanne Berchtold, Maike Delic, Jürgen Eberle, Anja Ehrhardt, Christine E. Engeland, Henry Fechner, Karsten Geletneky, Katrin Goepfert, Per Sonne Holm, Stefan Kochanek, Florian Kreppel, Lea Krutzke, Florian Kühnel, Karl Sebastian Lang, Antonio Marchini, Markus Moehler, Michael D. Mühlebach, Ulrike Naumann, Roman Nawroth, Jürg Nüesch, Jean Rommelaere, Ulrich M. Lauer, Guy Ungerechts
Published 2021-07-01