Capsid and Genome Modification Strategies to Reduce the Immunogenicity of Adenoviral Vectors

by Florian Kreppel, Claudia Hagedorn
Published 2021-02-01

A Method for Visualization of Incoming Adenovirus Chromatin Complexes in Fixed and Living Cells.

by Tetsuro Komatsu, Denis Dacheux, Florian Kreppel, Kyosuke Nagata, Harald Wodrich
Published 2015-01-01

Genetic and Chemical Capsid Modifications of Adenovirus Vectors to Modulate Vector–Host Interactions

by Denice Weklak, Daniel Pembaur, Georgia Koukou, Franziska Jönsson, Claudia Hagedorn, Florian Kreppel
Published 2021-07-01

Covalent decoration of adenovirus vector capsids with the carbohydrate epitope αGal does not improve vector immunogenicity, but allows to study the in vivo fate of adenovirus immun...

by Ramona F Kratzer, Sigrid Espenlaub, Andrea Hoffmeister, Matthias W Kron, Florian Kreppel
Published 2017-01-01

Transcellular targeting of fiber- and hexon-modified adenovirus vectors across the brain microvascular endothelial cells in vitro.

by Johanna P Laakkonen, Tatjana Engler, Ignacio A Romero, Babette Weksler, Pierre-Olivier Couraud, Florian Kreppel, Stefan Kochanek
Published 2012-01-01

Traceless bioresponsive shielding of adenovirus hexon with HPMA copolymers maintains transduction capacity in vitro and in vivo.

by Jan-Michael Prill, Vladimír Subr, Noemi Pasquarelli, Tatjana Engler, Andrea Hoffmeister, Stefan Kochanek, Karel Ulbrich, Florian Kreppel
Published 2014-01-01

Improved Functionality of Exhausted Intrahepatic CXCR5+ CD8+ T Cells Contributes to Chronic Antigen Clearance Upon Immunomodulation

by Kingsley Gideon Kumashie, Marcin Cebula, Claudia Hagedorn, Florian Kreppel, Marina C. Pils, Friedrich Koch-Nolte, Björn Rissiek, Dagmar Wirth, Dagmar Wirth
Published 2021-02-01

Porin 1 Modulates Autophagy in Yeast

by Filomena Broeskamp, Elizabeth S. M. Edrich, Oskar Knittelfelder, Lisa Neuhaus, Thorsten Meyer, Jonas Heyden, Lukas Habernig, Florian Kreppel, Campbell W. Gourlay, Patrick Rockenfeller
Published 2021-09-01

Do Current Asthma-Preventive Measures Appropriately Face the World Health Organization's Concerns: A Study Presentation of a New Clinical, Prospective, Multicentric Pediatric Asthm...

by Malik Aydin, Malik Aydin, Ella A. Naumova, Soeren Lutz, Almut Meyer-Bahlburg, Wolfgang H. Arnold, Florian Kreppel, Anja Ehrhardt, Jan Postberg, Jan Postberg, Stefan Wirth
Published 2020-11-01

Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy

by Sandra M. Kallert, Stephanie Darbre, Weldy V. Bonilla, Mario Kreutzfeldt, Nicolas Page, Philipp Müller, Matthias Kreuzaler, Min Lu, Stéphanie Favre, Florian Kreppel, Max Löhning, Sanjiv A. Luther, Alfred Zippelius, Doron Merkler, Daniel D. Pinschewer
Published 2017-05-01

Virotherapy in Germany—Recent Activities in Virus Engineering, Preclinical Development, and Clinical Studies

by Dirk M. Nettelbeck, Mathias F. Leber, Jennifer Altomonte, Assia Angelova, Julia Beil, Susanne Berchtold, Maike Delic, Jürgen Eberle, Anja Ehrhardt, Christine E. Engeland, Henry Fechner, Karsten Geletneky, Katrin Goepfert, Per Sonne Holm, Stefan Kochanek, Florian Kreppel, Lea Krutzke, Florian Kühnel, Karl Sebastian Lang, Antonio Marchini, Markus Moehler, Michael D. Mühlebach, Ulrike Naumann, Roman Nawroth, Jürg Nüesch, Jean Rommelaere, Ulrich M. Lauer, Guy Ungerechts
Published 2021-07-01

A molecular tweezer antagonizes seminal amyloids and HIV infection

by Edina Lump, Laura M Castellano, Christoph Meier, Janine Seeliger, Nelli Erwin, Benjamin Sperlich, Christina M Stürzel, Shariq Usmani, Rebecca M Hammond, Jens von Einem, Gisa Gerold, Florian Kreppel, Kenny Bravo-Rodriguez, Thomas Pietschmann, Veronica M Holmes, David Palesch, Onofrio Zirafi, Drew Weissman, Andrea Sowislok, Burkhard Wettig, Christian Heid, Frank Kirchhoff, Tanja Weil, Frank-Gerrit Klärner, Thomas Schrader, Gal Bitan, Elsa Sanchez-Garcia, Roland Winter, James Shorter, Jan Münch
Published 2015-08-01