Replication and virus-induced transcriptome of HAdV-5 in normal host cells versus cancer cells--differences of relevance for adenoviral oncolysis.

by Dominik E Dorer, Frank Holtrup, Kurt Fellenberg, Johanna K Kaufmann, Sarah Engelhardt, Jörg D Hoheisel, Dirk M Nettelbeck
Published 2011-01-01

Adenoviruses using the cancer marker EphA2 as a receptor in vitro and in vivo by genetic ligand insertion into different capsid scaffolds.

by Michael Behr, Johanna K Kaufmann, Patrick Ketzer, Sarah Engelhardt, Martin Mück-Häusl, Pamela M Okun, Gabriele Petersen, Frank Neipel, Jessica C Hassel, Anja Ehrhardt, Alexander H Enk, Dirk M Nettelbeck
Published 2014-01-01

The HDAC Inhibitors Scriptaid and LBH589 Combined with the Oncolytic Virus Delta24-RGD Exert Enhanced Anti-Tumor Efficacy in Patient-Derived Glioblastoma Cells.

by Lotte M E Berghauser Pont, Anne Kleijn, Jenneke J Kloezeman, Wouter van den Bossche, Johanna K Kaufmann, Jeroen de Vrij, Sieger Leenstra, Clemens M F Dirven, Martine L M Lamfers
Published 2015-01-01