Functional genomics identifies predictive markers and clinically actionable resistance mechanisms to CDK4/6 inhibition in bladder cancer

by Zhichao Tong, Anuja Sathe, Benedikt Ebner, Pan Qi, Christian Veltkamp, Juergen E. Gschwend, Per Sonne Holm, Roman Nawroth
Published 2019-07-01

Moving oncolytic viruses into the clinic: clinical-grade production, purification, and characterization of diverse oncolytic viruses

by Guy Ungerechts, Sascha Bossow, Barbara Leuchs, Per S Holm, Jean Rommelaere, Matt Coffey, Rob Coffin, John Bell, Dirk M Nettelbeck
Published 2016-01-01

Combination of Talazoparib and Palbociclib as a Potent Treatment Strategy in Bladder Cancer

by Florian G. Klein, Charlène Granier, Yuling Zhao, Qi Pan, Zhichao Tong, Jürgen E. Gschwend, Per Sonne Holm, Roman Nawroth
Published 2021-04-01

STAT3/5 Inhibitors Suppress Proliferation in Bladder Cancer and Enhance Oncolytic Adenovirus Therapy

by Sruthi V. Hindupur, Sebastian C. Schmid, Jana Annika Koch, Ahmed Youssef, Eva-Maria Baur, Dongbiao Wang, Thomas Horn, Julia Slotta-Huspenina, Juergen E. Gschwend, Per Sonne Holm, Roman Nawroth
Published 2020-02-01

EGFR-Targeted Adenovirus Dendrimer Coating for Improved Systemic Delivery of the Theranostic NIS Gene

by Geoffrey K Grünwald, Alexandra Vetter, Kathrin Klutz, Michael J Willhauck, Nathalie Schwenk, Reingard Senekowitsch-Schmidtke, Markus Schwaiger, Christian Zach, Ernst Wagner, Burkhard Göke, Per S Holm, Manfred Ogris, Christine Spitzweg
Published 2013-01-01

Virotherapy in Germany—Recent Activities in Virus Engineering, Preclinical Development, and Clinical Studies

by Dirk M. Nettelbeck, Mathias F. Leber, Jennifer Altomonte, Assia Angelova, Julia Beil, Susanne Berchtold, Maike Delic, Jürgen Eberle, Anja Ehrhardt, Christine E. Engeland, Henry Fechner, Karsten Geletneky, Katrin Goepfert, Per Sonne Holm, Stefan Kochanek, Florian Kreppel, Lea Krutzke, Florian Kühnel, Karl Sebastian Lang, Antonio Marchini, Markus Moehler, Michael D. Mühlebach, Ulrike Naumann, Roman Nawroth, Jürg Nüesch, Jean Rommelaere, Ulrich M. Lauer, Guy Ungerechts
Published 2021-07-01