A High-Resolution Mass Spectrometry-Based Quantitative Metabolomic Workflow Highlights Defects in 5-Fluorouracil Metabolism in Cancer Cells with Acquired Chemoresistance

by Sanjay Shahi, Ching-Seng Ang, Suresh Mathivanan
Published 2020-05-01

Immiscible inclusion bodies formed by polyglutamine and poly(glycine-alanine) are enriched with distinct proteomes but converge in proteins that are risk factors for disease and in...

by Mona Radwan, Jordan D Lilley, Ching-Seng Ang, Gavin E Reid, Danny M Hatters
Published 2020-01-01

Exosomes from N-Myc amplified neuroblastoma cells induce migration and confer chemoresistance to non-N-Myc amplified cells: implications of intra-tumour heterogeneity

by Pamali Fonseka, Michael Liem, Cemil Ozcitti, Christopher G. Adda, Ching-Seng Ang, Suresh Mathivanan
Published 2019-12-01

Oestrogen Activates the MAP3K1 Cascade and β-Catenin to Promote Granulosa-like Cell Fate in a Human Testis-Derived Cell Line

by Melanie K. Stewart, Pascal Bernard, Ching-Seng Ang, Deidre M. Mattiske, Andrew J. Pask
Published 2021-09-01

Temporal Quantitative Proteomics Analysis of Neuroblastoma Cells Treated with Bovine Milk-Derived Extracellular Vesicles Highlights the Anti-Proliferative Properties of Milk-Derive...

by Pamali Fonseka, Taeyoung Kang, Sing Chee, Sai V. Chitti, Rahul Sanwlani, Ching-Seng Ang, Suresh Mathivanan
Published 2021-03-01

Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth

by Monisha Samuel, David Chisanga, Michael Liem, Shivakumar Keerthikumar, Sushma Anand, Ching-Seng Ang, Christopher G. Adda, Ellen Versteegen, Markandeya Jois, Suresh Mathivanan
Published 2017-07-01

Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability

by Yilin Kang, Michael James Baker, Michael Liem, Jade Louber, Matthew McKenzie, Ishara Atukorala, Ching-Seng Ang, Shivakumar Keerthikumar, Suresh Mathivanan, Diana Stojanovski
Published 2016-08-01

Changes in the Cytoplasmic Composition of Amino Acids and Proteins Observed in Staphylococcus aureus during Growth under Variable Growth Conditions Representative of the Human Woun...

by Mousa M Alreshidi, R Hugh Dunstan, Johan Gottfries, Margaret M Macdonald, Marcus J Crompton, Ching-Seng Ang, Nicholas A Williamson, Tim K Roberts
Published 2016-01-01

Dafachronic acid promotes larval development in Haemonchus contortus by modulating dauer signalling and lipid metabolism.

by Guangxu Ma, Tao Wang, Pasi K Korhonen, Neil D Young, Shuai Nie, Ching-Seng Ang, Nicholas A Williamson, Gavin E Reid, Robin B Gasser
Published 2019-07-01

Extracellular Vesicles From the Cotton Pathogen Fusarium oxysporum f. sp. vasinfectum Induce a Phytotoxic Response in Plants

by Mark R. Bleackley, Monisha Samuel, Donovan Garcia-Ceron, James A. McKenna, Rohan G. T. Lowe, Mohashin Pathan, Kening Zhao, Ching-Seng Ang, Suresh Mathivanan, Marilyn A. Anderson
Published 2020-01-01

A rigorous method to enrich for exosomes from brain tissue

by Laura J. Vella, Benjamin J. Scicluna, Lesley Cheng, Emma G. Bawden, Colin L. Masters, Ching-Seng Ang, Nicholas Willamson, Catriona McLean, Kevin J. Barnham, Andrew F. Hill
Published 2017-12-01

Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells

by Hina Kalra, Lahiru Gangoda, Pamali Fonseka, Sai V. Chitti, Michael Liem, Shivakumar Keerthikumar, Monisha Samuel, Stephanie Boukouris, Haidar Al Saffar, Christine Collins, Christopher G. Adda, Ching-Seng Ang, Suresh Mathivanan
Published 2019-12-01

Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine

by Gahana Advani, Ya Chee Lim, Bruno Catimel, Daisy Sio Seng Lio, Nadia L. Y. Ng, Anderly C. Chüeh, Mai Tran, Mohd Ishtiaq Anasir, Heather Verkade, Hong-Jian Zhu, Benjamin E. Turk, Thomas E. Smithgall, Ching-Seng Ang, Michael Griffin, Heung-Chin Cheng
Published 2017-08-01

High-quality nuclear genome for Sarcoptes scabiei-A critical resource for a neglected parasite.

by Pasi K Korhonen, Robin B Gasser, Guangxu Ma, Tao Wang, Andreas J Stroehlein, Neil D Young, Ching-Seng Ang, Deepani D Fernando, Hieng C Lu, Sara Taylor, Simone L Reynolds, Ehtesham Mofiz, Shivashankar H Najaraj, Harsha Gowda, Anil Madugundu, Santosh Renuse, Deborah Holt, Akhilesh Pandey, Anthony T Papenfuss, Katja Fischer
Published 2020-10-01

Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis

by Yasmin M. Ramdzan, Mikhail M. Trubetskov, Angelique R. Ormsby, Estella A. Newcombe, Xiaojing Sui, Mark J. Tobin, Marie N. Bongiovanni, Sally L. Gras, Grant Dewson, Jason M.L. Miller, Steven Finkbeiner, Nagaraj S. Moily, Jonathan Niclis, Clare L. Parish, Anthony W. Purcell, Michael J. Baker, Jacqueline A. Wilce, Saboora Waris, Diana Stojanovski, Till Böcking, Ching-Seng Ang, David B. Ascher, Gavin E. Reid, Danny M. Hatters
Published 2017-05-01

Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis

by Monisha Samuel, Pamali Fonseka, Rahul Sanwlani, Lahiru Gangoda, Sing Ho Chee, Shivakumar Keerthikumar, Alex Spurling, Sai V. Chitti, Damien Zanker, Ching-Seng Ang, Ishara Atukorala, Taeyoung Kang, Sanjay Shahi, Akbar L. Marzan, Christina Nedeva, Claire Vennin, Morghan C. Lucas, Lesley Cheng, David Herrmann, Mohashin Pathan, David Chisanga, Sean C. Warren, Kening Zhao, Nidhi Abraham, Sushma Anand, Stephanie Boukouris, Christopher G. Adda, Lanzhou Jiang, Tanmay M. Shekhar, Nikola Baschuk, Christine J. Hawkins, Amelia J. Johnston, Jacqueline Monique Orian, Nicholas J. Hoogenraad, Ivan K. Poon, Andrew F. Hill, Markandeya Jois, Paul Timpson, Belinda S. Parker, Suresh Mathivanan
Published 2021-06-01

A novel community driven software for functional enrichment analysis of extracellular vesicles data

by Mohashin Pathan, Shivakumar Keerthikumar, David Chisanga, Riccardo Alessandro, Ching-Seng Ang, Philip Askenase, Arsen O. Batagov, Alberto Benito-Martin, Giovanni Camussi, Aled Clayton, Federica Collino, Dolores Di Vizio, Juan Manuel Falcon-Perez, Pedro Fonseca, Pamali Fonseka, Simona Fontana, Yong Song Gho, An Hendrix, Esther Nolte-’t Hoen, Nunzio Iraci, Kenneth Kastaniegaard, Thomas Kislinger, Joanna Kowal, Igor V. Kurochkin, Tommaso Leonardi, Yaxuan Liang, Alicia Llorente, Taral R. Lunavat, Sayantan Maji, Francesca Monteleone, Anders Øverbye, Theocharis Panaretakis, Tushar Patel, Héctor Peinado, Stefano Pluchino, Simona Principe, Goran Ronquist, Felix Royo, Susmita Sahoo, Cristiana Spinelli, Allan Stensballe, Clotilde Théry, Martijn J.C. van Herwijnen, Marca Wauben, Joanne L. Welton, Kening Zhao, Suresh Mathivanan
Published 2017-12-01