Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer’s and Parkinson’s Disease

by Laura J. Vella, Andrew F. Hill, Lesley Cheng
Published 2016-02-01

The role of extracellular vesicles in malaria biology and pathogenesis

by Natalia Guimaraes Sampaio, Lesley Cheng, Emily M. Eriksson
Published 2017-06-01

Modulation of cellular Hsp72 levels in undifferentiated and neuron-like SH-SY5Y cells determines resistance to staurosporine-induced apoptosis.

by Lesley Cheng, Danielle J Smith, Robin L Anderson, Phillip Nagley
Published 2011-01-01

Small RNA fingerprinting of Alzheimer’s disease frontal cortex extracellular vesicles and their comparison with peripheral extracellular vesicles

by Lesley Cheng, Laura J. Vella, Kevin J. Barnham, Catriona McLean, Colin L. Masters, Andrew F. Hill
Published 2020-01-01

Small Extracellular Vesicle Enrichment of a Retrotransposon-Derived Double-Stranded RNA: A Means to Avoid Autoinflammation?

by Marilou H. Barrios, Alexandra L. Garnham, Andrew D. Foers, Lesley Cheng-Sim, Seth L. Masters, Ken C. Pang
Published 2021-09-01

Revealing the Proteome of Motor Cortex Derived Extracellular Vesicles Isolated from Amyotrophic Lateral Sclerosis Human Postmortem Tissues

by Natasha Vassileff, Laura J. Vella, Harinda Rajapaksha, Mitch Shambrook, Amirmohammad Nasiri Kenari, Catriona McLean, Andrew F. Hill, Lesley Cheng
Published 2020-07-01

Extracellular Vesicles in Synovial Fluid from Rheumatoid Arthritis Patients Contain miRNAs with Capacity to Modulate Inflammation

by Andrew D. Foers, Alexandra L. Garnham, Simon Chatfield, Gordon K. Smyth, Lesley Cheng, Andrew F. Hill, Ian P. Wicks, Ken C. Pang
Published 2021-05-01

Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease

by Lesley Cheng, Camelia Quek, Xia Li, Shayne A. Bellingham, Laura J. Ellett, Mitch Shambrook, Saima Zafar, Inga Zerr, Victoria A. Lawson, Andrew F. Hill
Published 2021-03-01

Differential blood miRNA expression in brain amyloid imaging-defined Alzheimer’s disease and controls

by Helen Zong Ying Wu, Anbupalam Thalamuthu, Lesley Cheng, Christopher Fowler, Colin L. Masters, Perminder Sachdev, Karen A. Mather, and the Australian Imaging Biomarkers and Lifestyle Flagship Study of Ageing
Published 2020-05-01

Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography

by Andrew D. Foers, Simon Chatfield, Laura F. Dagley, Benjamin J. Scicluna, Andrew I. Webb, Lesley Cheng, Andrew F. Hill, Ian P. Wicks, Ken C. Pang
Published 2018-12-01

Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles

by Yiyao Huang, Lesley Cheng, Andrey Turchinovich, Vasiliki Mahairaki, Juan C. Troncoso, Olga Pletniková, Norman J. Haughey, Laura J. Vella, Andrew F. Hill, Lei Zheng, Kenneth W. Witwer
Published 2020-01-01

A rigorous method to enrich for exosomes from brain tissue

by Laura J. Vella, Benjamin J. Scicluna, Lesley Cheng, Emma G. Bawden, Colin L. Masters, Ching-Seng Ang, Nicholas Willamson, Catriona McLean, Kevin J. Barnham, Andrew F. Hill
Published 2017-12-01

Staphylococcus aureus membrane vesicles contain immunostimulatory DNA, RNA and peptidoglycan that activate innate immune receptors and induce autophagy

by Natalie J. Bitto, Lesley Cheng, Ella L. Johnston, Rishi Pathirana, Thanh Kha Phan, Ivan K. H. Poon, Neil M. O'Brien‐Simpson, Andrew F. Hill, Timothy P. Stinear, Maria Kaparakis‐Liaskos
Published 2021-04-01

HIV disease, metabolic dysfunction and atherosclerosis: A three year prospective study.

by Hann Low, Anh Hoang, Tatiana Pushkarsky, Larisa Dubrovsky, Elizabeth Dewar, Maria-Silvana Di Yacovo, Nigora Mukhamedova, Lesley Cheng, Catherine Downs, Gary Simon, Maria Saumoy, Andrew F Hill, Michael L Fitzgerald, Paul Nestel, Anthony Dart, Jennifer Hoy, Michael Bukrinsky, Dmitri Sviridov
Published 2019-01-01

Mitochondrial RNA in Alzheimer’s Disease Circulating Extracellular Vesicles

by Kyoung Mi Kim, Kyoung Mi Kim, Qiong Meng, Olivia Perez de Acha, Maja Mustapic, Aiwu Cheng, Erden Eren, Gautam Kundu, Yulan Piao, Rachel Munk, William H. Wood, Supriyo De, Ji Heon Noh, Michael Delannoy, Lesley Cheng, Kotb Abdelmohsen, Dimitrios Kapogiannis, Myriam Gorospe
Published 2020-11-01

Sex-specific transcriptional and proteomic signatures in schizophrenia

by Jari Tiihonen, Marja Koskuvi, Markus Storvik, Ida Hyötyläinen, Yanyan Gao, Katja A. Puttonen, Raisa Giniatullina, Ekaterina Poguzhelskaya, Ilkka Ojansuu, Olli Vaurio, Tyrone D. Cannon, Jouko Lönnqvist, Sebastian Therman, Jaana Suvisaari, Jaakko Kaprio, Lesley Cheng, Andrew F. Hill, Markku Lähteenvuo, Jussi Tohka, Rashid Giniatullin, Šárka Lehtonen, Jari Koistinaho
Published 2019-09-01

Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles

by Aled Clayton, Eric Boilard, Edit I Buzas, Lesley Cheng, Juan Manual Falcón-Perez, Chris Gardiner, Dakota Gustafson, Alice Gualerzi, An Hendrix, Andrew Hoffman, Jennifer Jones, Cecilia Lässer, Charlotte Lawson, Metka Lenassi, Irina Nazarenko, Lorraine O’Driscoll, Ryan Pink, Pia R-M Siljander, Carolina Soekmadji, Marca Wauben, Joshua A Welsh, Ken Witwer, Lei Zheng, Rienk Nieuwland
Published 2019-12-01

Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors

by Xavier Sisquella, Yifat Ofir-Birin, Matthew A. Pimentel, Lesley Cheng, Paula Abou Karam, Natália G. Sampaio, Jocelyn Sietsma Penington, Dympna Connolly, Tal Giladi, Benjamin J. Scicluna, Robyn A. Sharples, Andreea Waltmann, Dror Avni, Eli Schwartz, Louis Schofield, Ziv Porat, Diana S. Hansen, Anthony T. Papenfuss, Emily M. Eriksson, Motti Gerlic, Andrew F. Hill, Andrew G. Bowie, Neta Regev-Rudzki
Published 2017-12-01

Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017

by Aled Clayton, Dominik Buschmann, J. Brian Byrd, David R. F. Carter, Lesley Cheng, Carolyn Compton, George Daaboul, Andrew Devitt, Juan Manuel Falcon-Perez, Chris Gardiner, Dakota Gustafson, Paul Harrison, Clemens Helmbrecht, An Hendrix, Andrew Hill, Andrew Hoffman, Jennifer C. Jones, Raghu Kalluri, Ji Yoon Kang, Benedikt Kirchner, Cecilia Lässer, Charlotte Lawson, Metka Lenassi, Carina Levin, Alicia Llorente, Elena S. Martens-Uzunova, Andreas Möller, Luca Musante, Takahiro Ochiya, Ryan C Pink, Hidetoshi Tahara, Marca H. M. Wauben, Jason P. Webber, Joshua A. Welsh, Kenneth W. Witwer, Hang Yin, Rienk Nieuwland
Published 2018-12-01

Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis

by Monisha Samuel, Pamali Fonseka, Rahul Sanwlani, Lahiru Gangoda, Sing Ho Chee, Shivakumar Keerthikumar, Alex Spurling, Sai V. Chitti, Damien Zanker, Ching-Seng Ang, Ishara Atukorala, Taeyoung Kang, Sanjay Shahi, Akbar L. Marzan, Christina Nedeva, Claire Vennin, Morghan C. Lucas, Lesley Cheng, David Herrmann, Mohashin Pathan, David Chisanga, Sean C. Warren, Kening Zhao, Nidhi Abraham, Sushma Anand, Stephanie Boukouris, Christopher G. Adda, Lanzhou Jiang, Tanmay M. Shekhar, Nikola Baschuk, Christine J. Hawkins, Amelia J. Johnston, Jacqueline Monique Orian, Nicholas J. Hoogenraad, Ivan K. Poon, Andrew F. Hill, Markandeya Jois, Paul Timpson, Belinda S. Parker, Suresh Mathivanan
Published 2021-06-01