Patient-Derived Midbrain Organoids to Explore the Molecular Basis of Parkinson's Disease

by Benjamin Galet, Hélène Cheval, Philippe Ravassard
Published 2020-09-01

Beta cells within single human islets originate from multiple progenitors.

by Raphaël Scharfmann, Xiangwei Xiao, Harry Heimberg, Jacques Mallet, Philippe Ravassard
Published 2008-01-01

Epithelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells.

by Holger A Russ, Philippe Ravassard, Julie Kerr-Conte, Francois Pattou, Shimon Efrat
Published 2009-07-01

Quantitative comparison of constitutive promoters in human ES cells.

by Karin Norrman, Yvonne Fischer, Blandine Bonnamy, Fredrik Wolfhagen Sand, Philippe Ravassard, Henrik Semb
Published 2010-01-01

Directed pancreatic acinar differentiation of mouse embryonic stem cells via embryonic signalling molecules and exocrine transcription factors.

by Fabien Delaspre, Mohammad Massumi, Marta Salido, Bernat Soria, Philippe Ravassard, Pierre Savatier, Anouchka Skoudy
Published 2013-01-01

Co-Transplantation of VEGF-Expressing Human Embryonic Stem Cell Derived Mesenchymal Stem Cells to Enhance Islet Revascularization in Diabetic Nude Mice

by Ensiyeh Hajizadeh, Yaser Tahamtani, Mohammad Ali Shokrgozar, Harry Heimberg, Yves Heremans, Philippe Ravassard, Hossein Baharvand
Published 2014-05-01

A new strategy to generate functional insulin-producing cell lines by somatic gene transfer into pancreatic progenitors.

by Philippe Ravassard, Emilie Bricout-Neveu, Yasmine Hazhouz, Severine Pechberty, Jacques Mallet, Paul Czernichow, Raphael Scharfmann
Published 2009-01-01

A distal intergenic region controls pancreatic endocrine differentiation by acting as a transcriptional enhancer and as a polycomb response element.

by Joris van Arensbergen, Sebastien Dussaud, Corinne Pardanaud-Glavieux, Javier García-Hurtado, Claire Sauty, Aline Guerci, Jorge Ferrer, Philippe Ravassard
Published 2017-01-01

Differentiation of Sendai Virus-Reprogrammed iPSC into β Cells, Compared with Human Pancreatic Islets and Immortalized β Cell Line

by Silvia Pellegrini, Fabio Manenti, Raniero Chimienti, Rita Nano, Linda Ottoboni, Francesca Ruffini, Gianvito Martino, Philippe Ravassard, Lorenzo Piemonti, Valeria Sordi
Published 2018-10-01

Characterization of stimulus-secretion coupling in the human pancreatic EndoC-βH1 beta cell line.

by Lotta E Andersson, Bérengère Valtat, Annika Bagge, Vladimir V Sharoyko, David G Nicholls, Philippe Ravassard, Raphael Scharfmann, Peter Spégel, Hindrik Mulder
Published 2015-01-01

Human Liver Cells Expressing Albumin and Mesenchymal Characteristics Give Rise to Insulin-Producing Cells

by Irit Meivar-Levy, Tamar Sapir, Dana Berneman, Tal Weissbach, Sylvie Polak-Charcon, Philippe Ravassard, Andreas G. Tzakis, Eytan Mor, Camillo Ricordi, Sarah Ferber
Published 2011-01-01

Ectopic PDX-1 expression directly reprograms human keratinocytes along pancreatic insulin-producing cells fate.

by Michal Mauda-Havakuk, Naomi Litichever, Ellad Chernichovski, Odelia Nakar, Eyal Winkler, Ram Mazkereth, Arie Orenstein, Eran Bar-Meir, Philippe Ravassard, Irit Meivar-Levy, Sarah Ferber
Published 2011-01-01

Insulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitro.

by Holger A Russ, Elad Sintov, Leeat Anker-Kitai, Orr Friedman, Ayelet Lenz, Ginat Toren, Chen Farhy, Metsada Pasmanik-Chor, Varda Oron-Karni, Philippe Ravassard, Shimon Efrat
Published 2011-01-01

Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming.

by Nathalie Swales, Geert A Martens, Stefan Bonné, Yves Heremans, Rehannah Borup, Mark Van de Casteele, Zhidong Ling, Daniel Pipeleers, Philippe Ravassard, Finn Nielsen, Jorge Ferrer, Harry Heimberg
Published 2012-01-01

A human beta cell line with drug inducible excision of immortalizing transgenes

by Marion Benazra, Marie-José Lecomte, Claire Colace, Andreas Müller, Cécile Machado, Severine Pechberty, Emilie Bricout-Neveu, Maud Grenier-Godard, Michele Solimena, Raphaël Scharfmann, Paul Czernichow, Philippe Ravassard
Published 2015-12-01

Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene

by Ildem Akerman, Miguel Angel Maestro, Elisa De Franco, Vanessa Grau, Sarah Flanagan, Javier García-Hurtado, Gerhard Mittler, Philippe Ravassard, Lorenzo Piemonti, Sian Ellard, Andrew T. Hattersley, Jorge Ferrer
Published 2021-04-01

Tumor and Endothelial Cell Hybrids Participate in Glioblastoma Vasculature

by Soufiane El Hallani, Carole Colin, Younas El Houfi, Ahmed Idbaih, Blandine Boisselier, Yannick Marie, Philippe Ravassard, Marianne Labussière, Karima Mokhtari, Jean-Léon Thomas, Jean-Yves Delattre, Anne Eichmann, Marc Sanson
Published 2014-01-01

MiR-132 controls pancreatic beta cell proliferation and survival through Pten/Akt/Foxo3 signaling

by Hassan Mziaut, Georg Henniger, Katharina Ganss, Sebastian Hempel, Steffen Wolk, Johanna McChord, Kamal Chowdhury, Philippe Ravassard, Klaus-Peter Knoch, Christian Krautz, Jürgen Weitz, Robert Grützmann, Christian Pilarsky, Michele Solimena, Stephan Kersting
Published 2020-01-01

The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells.

by Monica Courtney, Elisabet Gjernes, Noémie Druelle, Christophe Ravaud, Andhira Vieira, Nouha Ben-Othman, Anja Pfeifer, Fabio Avolio, Gunter Leuckx, Sandra Lacas-Gervais, Fanny Burel-Vandenbos, Damien Ambrosetti, Jacob Hecksher-Sorensen, Philippe Ravassard, Harry Heimberg, Ahmed Mansouri, Patrick Collombat
Published 2013-10-01

Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles

by Anne Prel, Vincent Caval, Régis Gayon, Philippe Ravassard, Christine Duthoit, Emmanuel Payen, Leila Maouche-Chretien, Alison Creneguy, Tuan Huy Nguyen, Nicolas Martin, Eric Piver, Raphaël Sevrain, Lucille Lamouroux, Philippe Leboulch, Frédéric Deschaseaux, Pascale Bouillé, Luc Sensébé, Jean-Christophe Pagès
Published 2015-01-01