Early structural and functional defects in synapses and myelinated axons in stratum lacunosum moleculare in two preclinical models for tauopathy.

by Hervé Maurin, Seon-Ah Chong, Igor Kraev, Heather Davies, Anna Kremer, Claire Marie Seymour, Benoit Lechat, Tomasz Jaworski, Peter Borghgraef, Herman Devijver, Geert Callewaert, Michael G Stewart, Fred Van Leuven
Published 2014-01-01

Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy

by Ana I. Rojo, Marta Pajares, Angel J. García-Yagüe, Izaskun Buendia, Fred Van Leuven, Masayuki Yamamoto, Manuela G. López, Antonio Cuadrado
Published 2018-09-01

Effects of tauopathy on the morphological properties of fan and stellate cells in the entorhinal cortex of the P301S mutant mouse model

by Fowler, Michael
Published 2017

Long-term oral lithium treatment attenuates motor disturbance in tauopathy model mice: Implications of autophagy promotion

by Kohei Shimada, Yumiko Motoi, Koichi Ishiguro, Taiki Kambe, Shin-ei Matsumoto, Masako Itaya, Miyuki Kunichika, Hideo Mori, Atsuko Shinohara, Momoko Chiba, Yoshikuni Mizuno, Takashi Ueno, Nobutaka Hattori
Published 2012-04-01

Microarray analysis of CA1 pyramidal neurons in a mouse model of tauopathy reveals progressive synaptic dysfunction

by Melissa J. Alldred, Karen E. Duff, Stephen D. Ginsberg
Published 2012-02-01

TOC1: A valuable tool in assessing disease progression in the rTg4510 mouse model of tauopathy

by Sarah M. Ward, Diana S. Himmelstein, Yan Ren, Yifan Fu, Xiao-Wen Yu, Kaleigh Roberts, Lester I. Binder, Naruhiko Sahara
Published 2014-07-01

Tau-mediated dysregulation of RNA: Evidence for a common molecular mechanism of toxicity in frontotemporal dementia and other tauopathies

by Shon A. Koren, Sara Galvis-Escobar, Jose F. Abisambra
Published 2020-07-01

Phosphorylated NF-κB subunit p65 aggregates in granulovacuolar degeneration and neurites in neurodegenerative diseases with tauopathy

by Yamaguchi, Yuko
Published 2020

Chemoinformatics Analyses of Tau Ligands Reveal Key Molecular Requirements for the Identification of Potential Drug Candidates against Tauopathies

by Luca Pinzi, Annachiara Tinivella, Giulio Rastelli
Published 2021-08-01

Phosphorylation and oligomerization of α-synuclein associated with GSK-3β activation in the rTg4510 mouse model of tauopathy

by Yuta Takaichi, James K. Chambers, Hiroyuki Inoue, Yasuhisa Ano, Akihiko Takashima, Hiroyuki Nakayama, Kazuyuki Uchida
Published 2020-06-01

Correction to: Surfen and oxalyl surfen decrease tau hyperphosphorylation and mitigate neuron deficits in vivo in a zebrafish model of tauopathy

by Seyedeh Maryam Alavi Naini, Constantin Yanicostas, Rahma Hassan-Abdi, Sébastien Blondeel, Mohamed Bennis, Ryan J. Weiss, Yitzhak Tor, Jeffrey D. Esko, Nadia Soussi-Yanicostas
Published 2020-12-01

CX3CR1-deficient microglia shows impaired signalling of the transcription factor NRF2: Implications in tauopathies

by Sara Castro-Sánchez, Ángel J. García-Yagüe, Sebastian Kügler, Isabel Lastres-Becker
Published 2019-04-01

A novel triple repeat mutant tau transgenic model that mimics aspects of pick's disease and fronto-temporal tauopathies.

by Edward Rockenstein, Cassia R Overk, Kiren Ubhi, Michael Mante, Christina Patrick, Anthony Adame, Alejandro Bisquert, Margarita Trejo-Morales, Brian Spencer, Eliezer Masliah
Published 2015-01-01

An epigenetic signature in peripheral blood associated with the haplotype on 17q21.31, a risk factor for neurodegenerative tauopathy.

by Yun Li, Jason A Chen, Renee L Sears, Fuying Gao, Eric D Klein, Anna Karydas, Michael D Geschwind, Howard J Rosen, Adam L Boxer, Weilong Guo, Matteo Pellegrini, Steve Horvath, Bruce L Miller, Daniel H Geschwind, Giovanni Coppola
Published 2014-03-01

Chronic PD-1 Checkpoint Blockade Does Not Affect Cognition or Promote Tau Clearance in a Tauopathy Mouse Model

by Yan Lin, Hameetha B. Rajamohamedsait, Leslie A. Sandusky-Beltran, Begona Gamallo-Lana, Adam Mar, Einar M. Sigurdsson, Einar M. Sigurdsson
Published 2020-01-01

Accumulation of Vesicle-Associated Human Tau in Distal Dendrites Drives Degeneration and Tau Secretion in an In Situ Cellular Tauopathy Model

by Sangmook Lee, WonHee Kim, Zhihan Li, Garth F. Hall
Published 2012-01-01

Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models.

by Sethu Sankaranarayanan, Donna M Barten, Laurel Vana, Nino Devidze, Ling Yang, Gregory Cadelina, Nina Hoque, Lynn DeCarr, Stefanie Keenan, Alan Lin, Yang Cao, Bradley Snyder, Bin Zhang, Magdalena Nitla, Gregg Hirschfeld, Nestor Barrezueta, Craig Polson, Paul Wes, Vangipuram S Rangan, Angela Cacace, Charles F Albright, Jere Meredith, John Q Trojanowski, Virginia M-Y Lee, Kurt R Brunden, Michael Ahlijanian
Published 2015-01-01

Behavioural Functions and Cerebral Blood Flow in a P301S Tauopathy Mouse Model: A Time-Course Study

by Faraz Ahmad, Hannah Mein, Yu Jing, Hu Zhang, Ping Liu
Published 2021-09-01

Cleaved tau derived from human tauopathy brain induces disease-associated deficits in a novel mouse model

by Bondulich, Marie Katrin
Published 2016

Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice

by Eve Peeraer, Astrid Bottelbergs, Kristof Van Kolen, Ilie-Cosmin Stancu, Bruno Vasconcelos, Michel Mahieu, Hilde Duytschaever, Luc Ver Donck, An Torremans, Ellen Sluydts, Nathalie Van Acker, John A. Kemp, Marc Mercken, Kurt R. Brunden, John Q. Trojanowski, Ilse Dewachter, Virginia M.Y. Lee, Diederik Moechars
Published 2015-01-01