Three-Dimensional Visualization of APEX2-Tagged Erg11 in Saccharomyces cerevisiae Using Focused Ion Beam Scanning Electron Microscopy

by Winnie Kerstens, Anneke Kremer, Michelle Holtappels, Peter Borghgraef, Saskia Lippens, Patrick Van Dijck
Published 2020-02-01

Phosphorylation of protein Tau by GSK3β prolongs survival of bigenic Tau.P301L × GSK3β mice by delaying brainstem tauopathy

by Natalia Crespo-Biel, Clara Theunis, Peter Borghgraef, Benoit Lechat, Herman Devijver, Hervé Maurin, Fred Van Leuven
Published 2014-07-01

Age-related impairment of ultrasonic vocalization in Tau.P301L mice: possible implication for progressive language disorders.

by Clément Menuet, Yves Cazals, Christian Gestreau, Peter Borghgraef, Lies Gielis, Mathias Dutschmann, Fred Van Leuven, Gérard Hilaire
Published 2011-01-01

Isoflurane anesthesia precipitates tauopathy and upper airways dysfunction in pre-symptomatic Tau.P301L mice: Possible implication for neurodegenerative diseases

by Clément Menuet, Peter Borghgraef, Nicolas Voituron, Christian Gestreau, Lies Gielis, Herman Devijver, Mathias Dutschmann, Fred Van Leuven, Gérard Hilaire
Published 2012-04-01

Tauopathy differentially affects cell adhesion molecules in mouse brain: early down-regulation of nectin-3 in stratum lacunosum moleculare.

by Hervé Maurin, Claire Marie Seymour, Benoit Lechat, Peter Borghgraef, Herman Devijver, Tomasz Jaworski, Mathias V Schmidt, Sebastian Kuegler, Fred Van Leuven
Published 2013-01-01

AAV-tau mediates pyramidal neurodegeneration by cell-cycle re-entry without neurofibrillary tangle formation in wild-type mice.

by Tomasz Jaworski, Ilse Dewachter, Benoit Lechat, Sophie Croes, Annelies Termont, David Demedts, Peter Borghgraef, Herman Devijver, Robert K Filipkowski, Leszek Kaczmarek, Sebastian Kügler, Fred Van Leuven
Published 2009-10-01

Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice.

by Peter Borghgraef, Clément Menuet, Clara Theunis, Justin V Louis, Herman Devijver, Hervé Maurin, Caroline Smet-Nocca, Guy Lippens, Gerard Hilaire, Harrie Gijsen, Dieder Moechars, Fred Van Leuven
Published 2013-01-01

Early structural and functional defects in synapses and myelinated axons in stratum lacunosum moleculare in two preclinical models for tauopathy.

by Hervé Maurin, Seon-Ah Chong, Igor Kraev, Heather Davies, Anna Kremer, Claire Marie Seymour, Benoit Lechat, Tomasz Jaworski, Peter Borghgraef, Herman Devijver, Geert Callewaert, Michael G Stewart, Fred Van Leuven
Published 2014-01-01

Efficacy and safety of a liposome-based vaccine against protein Tau, assessed in tau.P301L mice that model tauopathy.

by Clara Theunis, Natalia Crespo-Biel, Valérie Gafner, Maria Pihlgren, María Pilar López-Deber, Pedro Reis, David T Hickman, Oskar Adolfsson, Nathalie Chuard, Dorin Mlaki Ndao, Peter Borghgraef, Herman Devijver, Fred Van Leuven, Andrea Pfeifer, Andreas Muhs
Published 2013-01-01