Loss of Bin1 Promotes the Propagation of Tau Pathology

by Sara Calafate, William Flavin, Patrik Verstreken, Diederik Moechars
Published 2016-10-01

Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation

by Sara Calafate, Arjan Buist, Katarzyna Miskiewicz, Vinoy Vijayan, Guy Daneels, Bart de Strooper, Joris de Wit, Patrik Verstreken, Diederik Moechars
Published 2015-05-01

Fragment Binding to β‑Secretase 1 without Catalytic Aspartate Interactions Identified via Orthogonal Screening Approaches

by Frederik J. R. Rombouts, Richard Alexander, Erna Cleiren, Alex De Groot, Michel Carpentier, Joyce Dijkmans, Katleen Fierens, Stefan Masure, Diederik Moechars, Martina Palomino-Schätzlein, Antonio Pineda-Lucena, Andrés A. Trabanco, Daan Van Glabbeek, Ann Vos, Gary Tresadern
Published 2017-02-01

Tau association with synaptic vesicles causes presynaptic dysfunction

by Lujia Zhou, Joseph McInnes, Keimpe Wierda, Matthew Holt, Abigail G. Herrmann, Rosemary J. Jackson, Yu-Chun Wang, Jef Swerts, Jelle Beyens, Katarzyna Miskiewicz, Sven Vilain, Ilse Dewachter, Diederik Moechars, Bart De Strooper, Tara L. Spires-Jones, Joris De Wit, Patrik Verstreken
Published 2017-05-01

Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice

by Eve Peeraer, Astrid Bottelbergs, Kristof Van Kolen, Ilie-Cosmin Stancu, Bruno Vasconcelos, Michel Mahieu, Hilde Duytschaever, Luc Ver Donck, An Torremans, Ellen Sluydts, Nathalie Van Acker, John A. Kemp, Marc Mercken, Kurt R. Brunden, John Q. Trojanowski, Ilse Dewachter, Virginia M.Y. Lee, Diederik Moechars
Published 2015-01-01

Comparison of New Tau PET-Tracer Candidates With [F]T808 and [F]T807

by Lieven Declercq Pharmacist, Sofie Celen PhD, Joan Lecina PhD, Muneer Ahamed PhD, Thomas Tousseyn Prof, MD, PhD, Diederik Moechars PhD, Jesus Alcazar PhD, Manuela Ariza PhD, Katleen Fierens PhD, Astrid Bottelbergs PhD, Jonas Mariën PhD, Rik Vandenberghe Prof, MD, PhD, Ignacio Jose Andres PhD, Koen Van Laere Prof, MD, PhD, Alfons Verbruggen Prof, PhD, Guy Bormans Prof, PhD
Published 2016-01-01