BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers

by Kara N. Maxwell, Bradley Wubbenhorst, Brandon M. Wenz, Daniel De Sloover, John Pluta, Lyndsey Emery, Amanda Barrett, Adam A. Kraya, Ioannis N. Anastopoulos, Shun Yu, Yuchao Jiang, Hao Chen, Nancy R. Zhang, Nicole Hackman, Kurt D’Andrea, Robert Daber, Jennifer J. D. Morrissette, Nandita Mitra, Michael Feldman, Susan M. Domchek, Katherine L. Nathanson
Published 2017-08-01

Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos

by Amanda D Yzaguirre, Arun Padmanabhan, Eric D de Groh, Kurt A Engleka, Jun Li, Nancy A Speck, Jonathan A Epstein
Published 2015-10-01

Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes

by Anthony R. Angueira, Suzanne N. Shapira, Jeff Ishibashi, Samay Sampat, Jaimarie Sostre-Colón, Matthew J. Emmett, Paul M. Titchenell, Mitchell A. Lazar, Hee-Woong Lim, Patrick Seale
Published 2020-03-01

Phenotypic and functional analysis of malignant mesothelioma tumor-infiltrating lymphocytes

by Astero Klampatsa, Shaun M. O’Brien, Jeffrey C. Thompson, Abhishek S. Rao, Jason E. Stadanlick, Marina C. Martinez, Maria Liousia, Edward Cantu, Keith Cengel, Edmund K. Moon, Sunil Singhal, Evgeniy B. Eruslanov, Steven M. Albelda
Published 2019-09-01

Deletion of histone deacetylase 3 in adult beta cells improves glucose tolerance via increased insulin secretion

by Jarrett R. Remsberg, Benjamin N. Ediger, Wesley Y. Ho, Manashree Damle, Zhenghui Li, Christopher Teng, Cristina Lanzillotta, Doris A. Stoffers, Mitchell A. Lazar
Published 2017-01-01

Enhancing Chimeric Antigen Receptor T Cell Anti-tumor Function through Advanced Media Design

by Saba Ghassemi, Francisco J. Martinez-Becerra, Alyssa M. Master, Sarah A. Richman, David Heo, John Leferovich, Yitao Tu, Juan Carlos García-Cañaveras, Asma Ayari, Yinan Lu, Ai Wang, Joshua D. Rabinowitz, Michael C. Milone, Carl H. June, Roddy S. O’Connor
Published 2020-09-01

Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity

by Amber Tariq, JiaBei Lin, Meredith E. Jackrel, Christina D. Hesketh, Peter J. Carman, Korrie L. Mack, Rachel Weitzman, Craig Gambogi, Oscar A. Hernandez Murillo, Elizabeth A. Sweeny, Esin Gurpinar, Adam L. Yokom, Stephanie N. Gates, Keolamau Yee, Saurabh Sudesh, Jacob Stillman, Alexandra N. Rizo, Daniel R. Southworth, James Shorter
Published 2019-08-01

An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides

by Sean M. Armour, Jarrett R. Remsberg, Manashree Damle, Simone Sidoli, Wesley Y. Ho, Zhenghui Li, Benjamin A. Garcia, Mitchell A. Lazar
Published 2017-09-01

Therapeutic genetic variation revealed in diverse Hsp104 homologs

by Zachary M March, Katelyn Sweeney, Hanna Kim, Xiaohui Yan, Laura M Castellano, Meredith E Jackrel, JiaBei Lin, Edward Chuang, Edward Gomes, Corey W Willicott, Karolina Michalska, Robert P Jedrzejczak, Andrzej Joachimiak, Kim A Caldwell, Guy A Caldwell, Ophir Shalem, James Shorter
Published 2020-12-01

Hepatic AKT orchestrates adipose tissue thermogenesis via FGF21-dependent and -independent mechanisms

by Jaimarie Sostre-Colón, Kahealani Uehara, Anna E. Garcia Whitlock, Matthew J. Gavin, Jeff Ishibashi, Matthew J. Potthoff, Patrick Seale, Paul M. Titchenell
Published 2021-05-01

Case Report: Prolonged Survival Following EGFRvIII CAR T Cell Treatment for Recurrent Glioblastoma

by Joseph S. Durgin, Joseph S. Durgin, Joseph S. Durgin, Fraser Henderson, MacLean P. Nasrallah, MacLean P. Nasrallah, Suyash Mohan, Sumei Wang, Simon F. Lacey, Jan Joseph Melenhorst, Jan Joseph Melenhorst, Jan Joseph Melenhorst, Arati S. Desai, Arati S. Desai, John Y. K. Lee, Marcela V. Maus, Carl H. June, Carl H. June, Steven Brem, Steven Brem, Roddy S. O’Connor, Roddy S. O’Connor, Zev Binder, Zev Binder, Donald M. O’Rourke, Donald M. O’Rourke
Published 2021-05-01

Identification of a molecular basis for the juvenile sleep state

by Leela Chakravarti Dilley, Milan Szuperak, Naihua N Gong, Charlette E Williams, Ricardo Linares Saldana, David S Garbe, Mubarak Hussain Syed, Rajan Jain, Matthew S Kayser
Published 2020-03-01

A sleep state in Drosophila larvae required for neural stem cell proliferation

by Milan Szuperak, Matthew A Churgin, Austin J Borja, David M Raizen, Christopher Fang-Yen, Matthew S Kayser
Published 2018-02-01

A circadian clock regulates efflux by the blood-brain barrier in mice and human cells

by Shirley L. Zhang, Nicholas F. Lahens, Zhifeng Yue, Denice M. Arnold, Peter P. Pakstis, Jessica E. Schwarz, Amita Sehgal
Published 2021-01-01

Effects of systemic inflammation on relapse in early breast cancer

by Nicholas P. McAndrew, Lisa Bottalico, Clementina Mesaros, Ian A. Blair, Patricia Y. Tsao, Jennifer M. Rosado, Tapan Ganguly, Sarah J. Song, Phyllis A. Gimotty, Jun J. Mao, Angela DeMichele
Published 2021-01-01

Overexpression and deletion of phospholipid transfer protein reduce HDL mass and cholesterol efflux capacity but not macrophage reverse cholesterol transport

by Takashi Kuwano, Xin Bi, Eleonora Cipollari, Tomoyuki Yasuda, William R. Lagor, Hannah J. Szapary, Junichiro Tohyama, John S. Millar, Jeffrey T. Billheimer, Nicholas N. Lyssenko, Daniel J. Rader
Published 2017-04-01

Dynamic Changes in Gene Mutational Landscape With Preservation of Core Mutations in Mantle Cell Lymphoma Cells

by Qian Zhang, Hong Y. Wang, Xiaobin Liu, Michael H. Roth, Alex A. Shestov, Seung-Cheol Lee, Kanika Jain, Craig Soderquist, Qun-Bin Xiong, Marco Ruella, Honore Strauser, Jerry D. Glickson, Stephen J. Schuster, Andrzej Ptasznik, Andrzej Ptasznik, Mariusz A. Wasik, Mariusz A. Wasik
Published 2019-07-01

Sleep deprivation suppresses aggression in Drosophila

by Matthew S Kayser, Benjamin Mainwaring, Zhifeng Yue, Amita Sehgal
Published 2015-07-01

Limitations of the use of the MP-RAGE to identify neural changes in the brain: Recent cigarette smoking alters gray matter indices in the striatum

by Teresa R Franklin, Reagan R Wetherill, Kanchana eJagannathan, Nathan eHager, Charles P O'Brien, Anna Rose eChildress
Published 2015-01-01

Quantification of granuloma volume and response to treatment in cutaneous sarcoidosis using 3-dimensional high-frequency ultrasound scan

by Olaf Rodriguez, BS, Megan H. Noe, MD, Chandra Sehgal, PhD, Susan Schultz, RDMS, Misha Rosenbach, MD
Published 2017-11-01