A dual-genotype oligoastrocytoma with histologic, molecular, radiological and time-course features

by Mac Lean P. Nasrallah, Arati Desai, Donald M. O’Rourke, Lea F. Surrey, Joel M. Stein
Published 2020-07-01

Factors associated with increased survival after surgical resection of glioblastoma in octogenarians.

by Kalil G Abdullah, Ashwin Ramayya, Jayesh P Thawani, Lukasz Macyszyn, Maria Martinez-Lage, Donald M O'Rourke, Steven Brem
Published 2015-01-01

Population-based MRI atlases of spatial distribution are specific to patient and tumor characteristics in glioblastoma

by Michel Bilello, Hamed Akbari, Xiao Da, Jared M. Pisapia, Suyash Mohan, Ronald L. Wolf, Donald M. O’Rourke, Maria Martinez-Lage, Christos Davatzikos
Published 2016-01-01

High-Affinity Chimeric Antigen Receptor With Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms

by Radhika Thokala, Radhika Thokala, Zev A. Binder, Zev A. Binder, Yibo Yin, Yibo Yin, Logan Zhang, Logan Zhang, Jiasi Vicky Zhang, Jiasi Vicky Zhang, Daniel Y. Zhang, Daniel Y. Zhang, Michael C. Milone, Michael C. Milone, Guo-li Ming, Hongjun Song, Hongjun Song, Donald M. O’Rourke, Donald M. O’Rourke
Published 2021-09-01

Molecular and Clinical Characterization of UBE2S in Glioma as a Biomarker for Poor Prognosis and Resistance to Chemo-Radiotherapy

by Li Hu, Xingbo Cheng, Zev Binder, Zhibin Han, Yibo Yin, Donald M. O’Rourke, Sida Wang, Yumeng Feng, Changjiang Weng, Anhua Wu, Zhiguo Lin
Published 2021-05-01

PDGF-mediated mesenchymal transformation renders endothelial resistance to anti-VEGF treatment in glioblastoma

by Tianrun Liu, Wenjuan Ma, Haineng Xu, Menggui Huang, Duo Zhang, Zhenqiang He, Lin Zhang, Steven Brem, Donald M. O’Rourke, Yanqing Gong, Yonggao Mou, Zhenfeng Zhang, Yi Fan
Published 2018-08-01

Case Report: Prolonged Survival Following EGFRvIII CAR T Cell Treatment for Recurrent Glioblastoma

by Joseph S. Durgin, Joseph S. Durgin, Joseph S. Durgin, Fraser Henderson, MacLean P. Nasrallah, MacLean P. Nasrallah, Suyash Mohan, Sumei Wang, Simon F. Lacey, Jan Joseph Melenhorst, Jan Joseph Melenhorst, Jan Joseph Melenhorst, Arati S. Desai, Arati S. Desai, John Y. K. Lee, Marcela V. Maus, Carl H. June, Carl H. June, Steven Brem, Steven Brem, Roddy S. O’Connor, Roddy S. O’Connor, Zev Binder, Zev Binder, Donald M. O’Rourke, Donald M. O’Rourke
Published 2021-05-01

Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α

by Qirui Wang, Zhenqiang He, Menggui Huang, Tianrun Liu, Yanling Wang, Haineng Xu, Hao Duan, Peihong Ma, Lin Zhang, Scott S. Zamvil, Juan Hidalgo, Zhenfeng Zhang, Donald M. O’Rourke, Nadia Dahmane, Steven Brem, Yonggao Mou, Yanqing Gong, Yi Fan
Published 2018-02-01

Quantification of tumor microenvironment acidity in glioblastoma using principal component analysis of dynamic susceptibility contrast enhanced MR imaging

by Hamed Akbari, Anahita Fathi Kazerooni, Jeffrey B. Ware, Elizabeth Mamourian, Hannah Anderson, Samantha Guiry, Chiharu Sako, Catalina Raymond, Jingwen Yao, Steven Brem, Donald M. O’Rourke, Arati S. Desai, Stephen J. Bagley, Benjamin M. Ellingson, Christos Davatzikos, Ali Nabavizadeh
Published 2021-07-01

Immune landscapes associated with different glioblastoma molecular subtypes

by Maria Martinez-Lage, Timothy M. Lynch, Yingtao Bi, Carolina Cocito, Gregory P. Way, Sharmistha Pal, Josephine Haller, Rachel E. Yan, Amy Ziober, Aivi Nguyen, Manoj Kandpal, Donald M. O’Rourke, Jeffrey P. Greenfield, Casey S. Greene, Ramana V. Davuluri, Nadia Dahmane
Published 2019-11-01

Transcriptome signatures associated with meningioma progression

by Angela N. Viaene, Bo Zhang, Maria Martinez-Lage, Chaomei Xiang, Umberto Tosi, Jayesh P. Thawani, Busra Gungor, Yuankun Zhu, Laura Roccograndi, Logan Zhang, Robert L. Bailey, Phillip B. Storm, Donald M. O’Rourke, Adam C. Resnick, M. Sean Grady, Nadia Dahmane
Published 2019-04-01

Multivariate Analysis of Preoperative Magnetic Resonance Imaging Reveals Transcriptomic Classification of de novo Glioblastoma Patients

by Saima Rathore, Saima Rathore, Hamed Akbari, Hamed Akbari, Spyridon Bakas, Spyridon Bakas, Spyridon Bakas, Jared M. Pisapia, Jared M. Pisapia, Gaurav Shukla, Gaurav Shukla, Jeffrey D. Rudie, Xiao Da, Ramana V. Davuluri, Nadia Dahmane, Donald M. O'Rourke, Christos Davatzikos, Christos Davatzikos
Published 2019-12-01

Pervasive within-Mitochondrion Single-Nucleotide Variant Heteroplasmy as Revealed by Single-Mitochondrion Sequencing

by Jacqueline Morris, Young-Ji Na, Hua Zhu, Jae-Hee Lee, Hoa Giang, Alexandra V. Ulyanova, Gordon H. Baltuch, Steven Brem, H. Isaac Chen, David K. Kung, Timothy H. Lucas, Donald M. O’Rourke, John A. Wolf, M. Sean Grady, Jai-Yoon Sul, Junhyong Kim, James Eberwine
Published 2017-12-01

Primary Cell Culture of Live Neurosurgically Resected Aged Adult Human Brain Cells and Single Cell Transcriptomics

by Jennifer M. Spaethling, Young-Ji Na, Jaehee Lee, Alexandra V. Ulyanova, Gordon H. Baltuch, Thomas J. Bell, Steven Brem, H. Isaac Chen, Hannah Dueck, Stephen A. Fisher, Marcela P. Garcia, Mugdha Khaladkar, David K. Kung, Timothy H. Lucas Jr., Donald M. O’Rourke, Derek Stefanik, Jinhui Wang, John A. Wolf, Tamas Bartfai, M. Sean Grady, Jai-Yoon Sul, Junhyong Kim, James H. Eberwine
Published 2017-01-01

Checkpoint Blockade Reverses Anergy in IL-13Rα2 Humanized scFv-Based CAR T Cells to Treat Murine and Canine Gliomas

by Yibo Yin, Alina C. Boesteanu, Zev A. Binder, Chong Xu, Reiss A. Reid, Jesse L. Rodriguez, Danielle R. Cook, Radhika Thokala, Kristin Blouch, Bevin McGettigan-Croce, Logan Zhang, Christoph Konradt, Alexandria P. Cogdill, M. Kazim Panjwani, Shuguang Jiang, Denis Migliorini, Nadia Dahmane, Avery D. Posey, Jr., Carl H. June, Nicola J. Mason, Zhiguo Lin, Donald M. O’Rourke, Laura A. Johnson
Published 2018-12-01

Molecular Neuropathology in Practice: Clinical Profiling and Integrative Analysis of Molecular Alterations in Glioblastoma

by MacLean P. Nasrallah MD, PhD, Zev A. Binder MD, PhD, Derek A. Oldridge MD, PhD, Jianhua Zhao PhD, FACMG, David B. Lieberman MS, CGC, Jacquelyn J. Roth PhD, Christopher D. Watt MD, PhD, Shrey Sukhadia MS, Eva Klinman PhD, Robert D. Daber PhD, Arati Desai MD, Steven Brem MD, Donald M. O’Rourke MD, Jennifer J. D. Morrissette PhD
Published 2019-05-01