Current progress and questions in germline genetics of prostate cancer

by William B. Isaacs, Jianfeng Xu
Published 2019-01-01

Calcium signaling: an underlying link between cardiac disease and carcinogenesis

by Xuehong Xu, Steven P. Balk, William B. Isaacs, Jianjie Ma
Published 2018-06-01

Assembly of inflammation-related genes for pathway-focused genetic analysis.

by Matthew J Loza, Charles E McCall, Liwu Li, William B Isaacs, Jianfeng Xu, Bao-Li Chang
Published 2007-10-01

Genome-wide Association Study Identifies Genetic Determinants of Urine PCA3 Levels in Men

by Zhuo Chen, Jielin Sun, Seong-Tae Kim, Jack Groskopf, Junjie Feng, William B. Isaacs, Roger S. Rittmaster, Lynn D. Condreay, Siqun Lilly Zheng, Jianfeng Xu
Published 2013-04-01

Identification of new differentially methylated genes that have potential functional consequences in prostate cancer.

by Jin W Kim, Seong-Tae Kim, Aubrey R Turner, Tracey Young, Shelly Smith, Wennuan Liu, Johan Lindberg, Lars Egevad, Henrik Gronberg, William B Isaacs, Jianfeng Xu
Published 2012-01-01

Genetic Susceptibility for Low Testosterone in Men and Its Implications in Biology and Screening: Data from the UK Biobank

by Richard J. Fantus, Rong Na, Jun Wei, Zhuqing Shi, W. Kyle Resurreccion, Joshua A. Halpern, Omar Franco, Simon W. Hayward, William B. Isaacs, S. Lilly Zheng, Jianfeng Xu, Brian T. Helfand
Published 2021-07-01

Genome-wide Association Study Identifies Loci at ATF7IP and KLK2 Associated with Percentage of Circulating Free PSA

by Guangfu Jin, Siqun Lilly Zheng, Hans Lilja, Seong-Tae Kim, Sha Tao, Zhengrong Gao, Tracey Young, Fredrik Wiklund, Junjie Feng, William B. Isaacs, Roger S. Rittmaster, Henrik Gronberg, Lynn D. Condreay, Jielin Sun, Jianfeng Xu
Published 2013-01-01

Homozygous Deletions and Recurrent Amplifications Implicate New Genes Involved in Prostate Cancer

by Wennuan Liu, Chunmei Carol Xie, Yi Zhu, Tao Li, Jishan Sun, Yu Cheng, Charles M. Ewing, Sue Dalrymple, Aubrey R. Turner, Jielin Sun, John T. Isascs, Bao-Li Chang, Siqun Lilly Zheng, William B. Isaacs, Jianfeng Xu
Published 2008-08-01

Genome-wide association scan for variants associated with early-onset prostate cancer.

by Ethan M Lange, Anna M Johnson, Yunfei Wang, Kimberly A Zuhlke, Yurong Lu, Jessica V Ribado, Gregory R Keele, Jin Li, Qing Duan, Ge Li, Zhengrong Gao, Yun Li, Jianfeng Xu, William B Isaacs, Siqun Zheng, Kathleen A Cooney
Published 2014-01-01

Dynamics expression of DmFKBP12/Calstabin during embryonic early development of Drosophila melanogaster

by Rui Feng, Xin Zhou, Wei Zhang, Tao Pu, Yuting Sun, Rong Yang, Dan Wang, Xiaofei Zhang, Yingfeng Gao, Zhenlu Cai, Yu Liang, Qiuxia Yu, Yajun Wu, Xinjuan Lei, Zhijia Liang, Odell Jones, Liyang Wang, Mengmeng Xu, Yanping Sun, William B. Isaacs, Jianjie Ma, Xuehong Xu
Published 2019-01-01

CD38 is methylated in prostate cancer and regulates extracellular NAD+

by Jack Mottahedeh, Michael C. Haffner, Tristan R. Grogan, Takao Hashimoto, Preston D. Crowell, Himisha Beltran, Andrea Sboner, Rohan Bareja, David Esopi, William B. Isaacs, Srinivasan Yegnasubramanian, Matthew B. Rettig, David A. Elashoff, Elizabeth A. Platz, Angelo M. De Marzo, Michael A. Teitell, Andrew S. Goldstein
Published 2018-09-01

Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer

by W. Nathaniel Brennen, Yezi Zhu, Ilsa M. Coleman, Susan L. Dalrymple, Lizamma Antony, Radhika A. Patel, Brian Hanratty, Roshan Chikarmane, Alan K. Meeker, S. Lilly Zheng, Jody E. Hooper, Jun Luo, Angelo M. De Marzo, Eva Corey, Jianfeng Xu, Srinivasan Yegnasubramanian, Michael C. Haffner, Peter S. Nelson, William G. Nelson, William B. Isaacs, John T. Isaacs
Published 2021-04-01

AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination

by Michael C. Haffner, David M. Esopi, Alcides Chaux, Meltem Gürel, Susmita Ghosh, Ajay M. Vaghasia, Harrison Tsai, Kunhwa Kim, Nicole Castagna, Hong Lam, Jessica Hicks, Nicolas Wyhs, Debika Biswal Shinohara, Paula J. Hurley, Brian W. Simons, Edward M. Schaeffer, Tamara L. Lotan, William B. Isaacs, George J. Netto, Angelo M. De Marzo, William G. Nelson, Steven S. An, Srinivasan Yegnasubramanian
Published 2017-07-01

Combined Longitudinal Clinical and Autopsy Phenomic Assessment in Lethal Metastatic Prostate Cancer: Recommendations for Advancing Precision Medicine

by Juho Jasu, Teemu Tolonen, Emmanuel S. Antonarakis, Himisha Beltran, Susan Halabi, Mario A. Eisenberger, Michael A. Carducci, Yohann Loriot, Kim Van der Eecken, Martijn Lolkema, Charles J. Ryan, Sinja Taavitsainen, Silke Gillessen, Gunilla Högnäs, Timo Talvitie, Robert J. Taylor, Antti Koskenalho, Piet Ost, Teemu J. Murtola, Irina Rinta-Kiikka, Teuvo Tammela, Anssi Auvinen, Paula Kujala, Thomas J. Smith, Pirkko-Liisa Kellokumpu-Lehtinen, William B. Isaacs, Matti Nykter, Juha Kesseli, G. Steven Bova
Published 2021-08-01

Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans.

by Christopher A Haiman, Gary K Chen, William J Blot, Sara S Strom, Sonja I Berndt, Rick A Kittles, Benjamin A Rybicki, William B Isaacs, Sue A Ingles, Janet L Stanford, W Ryan Diver, John S Witte, Stephen J Chanock, Suzanne Kolb, Lisa B Signorello, Yuko Yamamura, Christine Neslund-Dudas, Michael J Thun, Adam Murphy, Graham Casey, Xin Sheng, Peggy Wan, Loreall C Pooler, Kristine R Monroe, Kevin M Waters, Loic Le Marchand, Laurence N Kolonel, Daniel O Stram, Brian E Henderson
Published 2011-05-01

Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies.

by Katherine S Elliott, Eleftheria Zeggini, Mark I McCarthy, Julius Gudmundsson, Patrick Sulem, Simon N Stacey, Steinunn Thorlacius, Laufey Amundadottir, Henrik Grönberg, Jianfeng Xu, Valerie Gaborieau, Rosalind A Eeles, David E Neal, Jenny L Donovan, Freddie C Hamdy, Kenneth Muir, Shih-Jen Hwang, Margaret R Spitz, Brent Zanke, Luis Carvajal-Carmona, Kevin M Brown, Australian Melanoma Family Study Investigators, Nicholas K Hayward, Stuart Macgregor, Ian P M Tomlinson, Mathieu Lemire, Christopher I Amos, Joanne M Murabito, William B Isaacs, Douglas F Easton, Paul Brennan, PanScan Consortium, Rosa B Barkardottir, Daniel F Gudbjartsson, Thorunn Rafnar, David J Hunter, Stephen J Chanock, Kari Stefansson, John P A Ioannidis
Published 2010-05-01

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

by Young Seok Ju, Ludmil B Alexandrov, Moritz Gerstung, Inigo Martincorena, Serena Nik-Zainal, Manasa Ramakrishna, Helen R Davies, Elli Papaemmanuil, Gunes Gundem, Adam Shlien, Niccolo Bolli, Sam Behjati, Patrick S Tarpey, Jyoti Nangalia, Charles E Massie, Adam P Butler, Jon W Teague, George S Vassiliou, Anthony R Green, Ming-Qing Du, Ashwin Unnikrishnan, John E Pimanda, Bin Tean Teh, Nikhil Munshi, Mel Greaves, Paresh Vyas, Adel K El-Naggar, Tom Santarius, V Peter Collins, Richard Grundy, Jack A Taylor, D Neil Hayes, David Malkin, ICGC Breast Cancer Group, ICGC Chronic Myeloid Disorders Group, ICGC Prostate Cancer Group, Christopher S Foster, Anne Y Warren, Hayley C Whitaker, Daniel Brewer, Rosalind Eeles, Colin Cooper, David Neal, Tapio Visakorpi, William B Isaacs, G Steven Bova, Adrienne M Flanagan, P Andrew Futreal, Andy G Lynch, Patrick F Chinnery, Ultan McDermott, Michael R Stratton, Peter J Campbell
Published 2014-10-01

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

by Alexander Gusev, Huwenbo Shi, Gleb Kichaev, Mark Pomerantz, Fugen Li, Henry W. Long, Sue A. Ingles, Rick A. Kittles, Sara S. Strom, Benjamin A. Rybicki, Barbara Nemesure, William B. Isaacs, Wei Zheng, Curtis A. Pettaway, Edward D. Yeboah, Yao Tettey, Richard B. Biritwum, Andrew A. Adjei, Evelyn Tay, Ann Truelove, Shelley Niwa, Anand P. Chokkalingam, Esther M. John, Adam B. Murphy, Lisa B. Signorello, John Carpten, M. Cristina Leske, Suh-Yuh Wu, Anslem J. M. Hennis, Christine Neslund-Dudas, Ann W. Hsing, Lisa Chu, Phyllis J. Goodman, Eric A. Klein, John S. Witte, Graham Casey, Sam Kaggwa, Michael B. Cook, Daniel O. Stram, William J. Blot, Rosalind A. Eeles, Douglas Easton, ZSofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch, Kenneth Muir, Graham G. Giles, Melissa C. Southey, Liesel M. Fitzgerald, Henrik Gronberg, Fredrik Wiklund, Markus Aly, Brian E. Henderson, Johanna Schleutker, Tiina Wahlfors, Teuvo L. J. Tammela, Børge G. Nordestgaard, Tim J. Key, Ruth C. Travis, David E. Neal, Jenny L. Donovan, Freddie C. Hamdy, Paul Pharoah, Nora Pashayan, Kay-Tee Khaw, Janet L. Stanford, Stephen N. Thibodeau, Shannon K. McDonnell, Daniel J. Schaid, Christiane Maier, Walther Vogel, Manuel Luedeke, Kathleen Herkommer, Adam S. Kibel, Cezary Cybulski, Dominika Wokolorczyk, Wojciech Kluzniak, Lisa Cannon-Albright, Craig Teerlink, Hermann Brenner, Aida K. Dieffenbach, Volker Arndt, Jong Y. Park, Thomas A. Sellers, Hui-Yi Lin, Chavdar Slavov, Radka Kaneva, Vanio Mitev, Jyotsna Batra, Amanda Spurdle, Judith A. Clements, Manuel R. Teixeira, Hardev Pandha, Agnieszka Michael, Paula Paulo, Sofia Maia, Andrzej Kierzek, The PRACTICAL consortium, David V. Conti, Demetrius Albanes, Christine Berg, Sonja I. Berndt, Daniele Campa, E. David Crawford, W. Ryan Diver, Susan M. Gapstur, J. Michael Gaziano, Edward Giovannucci, Robert Hoover, David J. Hunter, Mattias Johansson, Peter Kraft, Loic Le Marchand, Sara Lindström, Carmen Navarro, Kim Overvad, Elio Riboli, Afshan Siddiq, Victoria L. Stevens, Dimitrios Trichopoulos, Paolo Vineis, Meredith Yeager, Gosia Trynka, Soumya Raychaudhuri, Frederick R. Schumacher, Alkes L. Price, Matthew L. Freedman, Christopher A. Haiman, Bogdan Pasaniuc
Published 2016-04-01